recent publications

• academic article

  • Yang, C. J., Ruffner, M. A., Kim, S. H., Robbins, P. D. Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses European Journal of Immunology  2012 42:1778-1784  DOI:10.1002/eji.201141978  PMID:22585706  PMCID:PMC3471134
  • Bae, J. W., Choi, C. I., Kim, M. J., Oh, D. H., Keum, S. K., Park, J. I., Kim, B. H., Bang, H. K., Oh, S. G., Kang, B. S., Lee, H. I., Lee, Y. J., et al. Frequency of cyp2c9 alleles in koreans and their effects on losartan pharmacokinetics Acta Pharmacologica Sinica  2011 32:1303-1308  DOI:10.1038/aps.2011.100  PMID:21841812  PMCID:PMC4010224
  • Tian, Y. H., Kim, S. H., Lee, S. Y., Jang, C. G. Lactational and postnatal exposure to polychlorinated biphenyls induces sex-specific anxiolytic behavior and cognitive deficit in mice offspring Synapse  2011 65:1032-1041  DOI:10.1002/syn.20934  PMID:21425352
  • Yang, C. J., Kim, S. H., Bianco, N. R., Robbins, P. D. Tumor-derived exosomes confer antigen-specific immunosuppression in a murine delayed-type hypersensitivity model PLoS One  2011 6:e22517  DOI:10.1371/journal.pone.0022517  PMID:21829629  PMCID:PMC3149056
  • Reay, J., Kim, S. H., Lockhart, E., Kolls, J., Robbins, P. D. Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response Cancer Gene Therapy  2009 16:776-785  DOI:10.1038/cgt.2009.27  PMID:19390568  PMCID:PMC2745505
  • Ruffner, M. A., Kim, S. H., Bianco, N. R., Francisco, L. M., Sharpe, A. H., Robbins, P. D. B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function European Journal of Immunology  2009 39:3084-3090  DOI:10.1002/eji.200939407  PMID:19757438  PMCID:PMC3075967
  • Moon, E., Her, Y., Lee, J. B., Park, J. H., Lee, E. H., Kim, S. H., Oh, M. S., Jang, C. G., Kim, S. Y. The multi-herbal medicine gongjin-dan enhances memory and learning tasks via ngf regulation Neuroscience Letters  2009 466:114-119  DOI:10.1016/j.neulet.2009.09.033  PMID:19788912
  • Bianco, N. R., Kim, S. H., Ruffner, M. A., Robbins, P. D. Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models Arthritis and Rheumatism  2009 60:380-389  DOI:10.1002/art.24229  PMID:19180475  PMCID:PMC3491653
  • Lim, S., Choi, J. W., Kim, H. S., Kim, Y. H., Yea, K., Heo, K., Kim, J. H., Kim, S. H., Song, M., Kim II, J., Ryu, S. H., Suh, P. G. A myristoylated pseudosubstrate peptide of PKC-ζ induces degranulation in HMC-1 cells independently of PKC-ζ activity Life Sciences  2008 82:733-740  DOI:10.1016/j.lfs.2008.01.005  PMID:18289606
  • Graslund, S., Nordlund, P., Weigelt, J., Bray, J., Hallberg, B. M., Gileadi, O., Knapp, S., Oppermann, U., Arrowsmith, C., Hui, R., Ming, J., Dhe-Paganon, S., et al. Protein production and purification Nature Methods  2008 5:135-146  DOI:10.1038/nmeth.f.202  PMID:18235434  PMCID:PMC3178102
  • Yoo, E. J., Ahlquist, M., Kim, S. H., Bae, I., Fokin, V. V., Sharpless, K. B., Chang, S. Copper-catalyzed synthesis of N-sulfonyl-1,2,3-triazoles: controlling selectivity Angewandte Chemie-International Edition  2007 46:1730-1733  DOI:10.1002/anie.200604241  PMID:17397087
  • Kim, S. H., Bianco, N. R., Shufesky, W. J., Morelli, A. E., Robbins, P. D. Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express il-4 Journal of Immunology  2007 179:2242-2249  PMID:17675485
  • Kim, S. H., Bianco, N. R., Shufesky, W. J., Morelli, A. E., Robbins, P. D. MHC class II+ exosomes in plasma suppress inflammation in an antigen-specific and Fas ligand/Fas-dependent manner Journal of Immunology  2007 179:2235-2241  PMID:17675484
  • Kim, S. H., Bianco, N., Menon, R., Lechman, E. R., Shufesky, W. J., Morelli, A. E., Robbins, P. D. Exosomes derived from genetically modified dc expressing fasl are anti-inflammatory and immunosuppressive Molecular Therapy  2006 13:289-300  DOI:10.1016/j.ymthe.2005.09.015  PMID:16275099
  • Yoo, J. H., Yang, E. M., Cho, J. H., Lee, J. H., Jeong, S. M., Nah, S. Y., Kim, H. C., Kim, K. W., Kim, S. H., Lee, S. Y., Jang, C. G. Inhibitory effects of berberine against morphine-induced locomotor sensitization and analgesic tolerance in mice Neuroscience  2006 142:953-961  DOI:10.1016/j.neuroscience.2006.07.008  PMID:16934942
  • Kim, H. S., Yumkham, S., Kim, S. H., Yea, K., Shin, Y. C., Ryu, S. H., Suh, P. G. Secretin induces neurite outgrowth of PC12 through cAMP-mitogen-activated protein kinase pathway Experimental and Molecular Medicine  2006 38:85-93  PMID:16520556
  • Kim, S. H., Lechman, E. R., Bianco, N., Menon, R., Keravala, A., Nash, J., Mi, Z. B., Watkins, S. C., Gambotto, A., Robbins, P. D. Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis Journal of Immunology  2005 174:6440-6448  PMID:15879146
  • Kaneko, K., Wang, Z., Kim, S. H., Morelli, A. E., Robbins, P. D., Thomson, A. W. Dendritic cells genetically engineered to express IL-4 exhibit enhanced IL-12p70 production in response to CD40 ligation and accelerate organ allograft rejection Gene Therapy  2003 10:143-152  DOI:10.1038/sj.gt.3301872  PMID:12571643
  • Lechman, E. R., Keravala, A., Nash, J., Kim, S. H., Mi, Z., Robbins, P. D. The contralateral effect conferred by intra-articular adenovirus-mediated gene transfer of viral IL-10 is specific to the immunizing antigen Gene Therapy  2003 10:2029-2035  DOI:10.1038/sj.gt.3302109  PMID:14566362
  • Mukherjee, P., Wu, B., Mayton, L., Kim, S. H., Robbins, P. D., Wooley, P. H. Tnf receptor gene therapy results in suppression of igg2a anticollagen antibody in collagen induced arthritis Annals of the Rheumatic Diseases  2003 62:707-714  DOI:10.1136/ard.62.8.707  PMID:12860724  PMCID:PMC1754640
  • Kim, S. H., Kim, S., Oligino, T. J., Robbins, P. D. Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL Molecular Therapy  2002 6:584-590  DOI:10.1006/mthe.2002.0712  PMID:12409256
  • Kim, S. H., Lechman, E. R., Kim, S., Nash, J., Oligino, T. J., Robbins, P. D. Ex vivo gene delivery of il-1ra and soluble tnf receptor confers a distal synergistic therapeutic effect in antigen-induced arthritis Molecular Therapy  2002 6:591-600  DOI:10.1006/mthe.2002.0711  PMID:12409257
  • Mai, J. C., Mi, Z. B., Kim, S. H., Ng, B., Robbins, P. D. A proapoptotic peptide for the treatment of solid tumors Cancer Research  2001 61:7709-7712  PMID:11691780
  • Kim, S. H., Kim, S., Evans, C. H., Ghivizzani, S. C., Oligino, T., Robbins, P. D. Effective treatment of established murine collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express IL-4 Journal of Immunology  2001 166:3499-3505  PMID:11207309
  • Boger, D. L., Kim, S. H., Mori, Y., Weng, J. H., Rogel, O., Castle, S. L., McAtee, J. J. First and second generation total synthesis of the teicoplanin aglycon Journal of the American Chemical Society  2001 123:1862-1871  DOI:10.1021/ja003835i  PMID:11456806
  • Kang, W. K., Park, C., Yoon, H. L., Kim, W. S., Yoon, S. S., Lee, M. H., Park, K., Kim, K., Jeong, H. S., Kim, J. A., Nam, S. J., Yang, J. H., et al. Interleukin 12 gene therapy of cancer by peritumoral injection of transduced autologous fibroblasts: Outcome of a phase I study Human Gene Therapy  2001 12:671-684  DOI:10.1089/104303401300057388  PMID:11426466
  • Lim, H. K., Kim, H. S., Choi, H. S., Oh, S., Jang, C. G., Choi, J., Kim, S. H., Chang, M. J. Effects of acetylbergenin against d-galactosamine-induced hepatotoxicity in rats Pharmacological Research  2000 42:471-474  DOI:10.1006/phrs.2000.0730  PMID:11023710
  • Kim, S. H., Evans, C. H., Kim, S., Oligino, T., Ghivizzani, S. C., Robbins, P. D. Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4 Arthritis Research  2000 2:293-302  DOI:10.1186/ar104  PMID:11056670  PMCID:PMC17812
  • Kim, H. S., Park, I. S., Lim, H. K., Choi, H. S., Oh, S., Park, W. K., Jang, C. G., Kim, S. H., Chang, M. J. N-methyl-d-aspartate receptor antagonists enhance the head-twitch response, a 5-hydroxytryptamine(2) receptor-mediated behaviour, in reserpine-treated mice Journal of Pharmacy and Pharmacology  2000 52:717-722  DOI:10.1211/0022357001774390  PMID:10875549
  • Kim, S. H., Kim, S. Y., Robbins, P. D. Retroviral vectors Advances in Virus Research  2000 55:545-563  DOI:10.1016/s0065-3527(00)55017-9  PMID:11050956
  • Boger, D. L., Weng, J. H., Miyazaki, S., McAtee, J. J., Castle, S. L., Kim, S. H., Mori, Y., Rogel, O., Strittmatter, H., Jin, Q. Thermal atropisomerism of teicoplanin aglycon derivatives: Preparation of the P,P,P and M,P,P atropisomers of the teicoplanin aglycon via selective equilibration of the DE ring system Journal of the American Chemical Society  2000 122:10047-10055  DOI:10.1021/ja002376i
  • Boger, D. L., Kim, S. H., Miyazaki, S., Strittmatter, H., Weng, J. H., Mori, Y., Rogel, O., Castle, S. L., McAtee, J. J. Total synthesis of the teicoplanin aglycon Journal of the American Chemical Society  2000 122:7416-7417  DOI:10.1021/ja001663j
  • Boger, D. L., Miyazaki, S., Kim, S. H., Wu, J. H., Loiseleur, O., Castle, S. L. Diastereoselective total synthesis of the vancomycin aglycon with ordered atropisomer equilibrations Journal of the American Chemical Society  1999 121:3226-3227  DOI:10.1021/ja990189i
  • Nicolaou, K. C.*, Pfefferkorn, J.*, Xu, J. Y., Winssinger, N., Ohshima, T., Kim, S. H., Hosokawa, S., Vouruloumis, D., van Delft, F., Li, T. Total synthesis and chemical biology of the sarcodictyins Chemical & Pharmaceutical Bulletin  1999 47:1199-1213  PMID:10517002 (* = equal contribution)
  • Boger, D. L., Miyazaki, S., Kim, S. H., Wu, J. H., Castle, S. L., Loiseleur, O., Jin, Q. Total synthesis of the vancomycin aglycon Journal of the American Chemical Society  1999 121:10004-10011  DOI:10.1021/ja992577q
  • Kim, S. H., Yu, S. S., Park, J. S., Robbins, P. D., An, C. S., Kim, S. Construction of retroviral vectors with improved safety, gene expression, and versatility Journal of Virology  1998 72:994-1004  PMID:9444992  PMCID:PMC124570
  • Gray, N. S., Wodicka, L., Thunnissen, Amwh, Norman, T. C., Kwon, S. J., Espinoza, F. H., Morgan, D. O., Barnes, G., LeClerc, S., Meijer, L., Kim, S. H., Lockhart, D. J., et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors Science  1998 281:533-538  DOI:10.1126/science.281.5376.533  PMID:9677190
  • Nicolaou, K. C., Kim, S. H., Pfefferkorn, J., Xu, J. Y., Ohshima, T., Hosokawa, S., Vourloumis, D., Li, T. Synthesis and biological activity of sarcodictyins Angewandte Chemie-International Edition  1998 37:1418-1421  DOI:10.1002/(sici)1521-3773(19980605)37:10<1418::aid-anie1418>3.0.co;2-5
  • Kim, S. H., An, C. S., Tahara, H., Park, C., Lotze, M. T., Robbins, P. D., Kim, S. Retroviral-mediated IL-12 gene therapy for advanced murine tumors Experimental and Molecular Medicine  1997 29:53-58  DOI:10.1038/emm.1997.8
  • Ribas de Pouplana, L., Auld, D. S., Kim, S. H., Schimmel, P. A mechanism for reducing entropic cost of induced fit in protein-RNA recognition Biochemistry  1996 35:8095-8102  DOI:10.1021/bi960256a  PMID:8679560
  • Byun, J., Kim, J. M., Kim, S. H., Yim, J., Robbins, P. D., Kim, S. A simple and rapid method for the determination of recombinant retrovirus titer by G418 selection Gene Therapy  1996 3:1018-1020  PMID:9044742
  • Byun, J., Kim, S. H., Kim, J. M., Yu, S. S., Robbins, P. D., Yim, J., Kim, S. Analysis of the relative level of gene expression from different retroviral vectors used for gene therapy Gene Therapy  1996 3:780-788  PMID:8875226
  • Kim, S. H., Ribas de Pouplana, L., Schimmel, P. An RNA binding site in a tRNA synthetase with a reduced set of amino acids Biochemistry  1994 33:11040-11045  DOI:10.1021/bi00202a025  PMID:7522052
  • Kim, S. H., Schimmel, P. Function independence of microhelix aminoacylation from anticodon binding in a class I tRNA synthetase Journal of Biological Chemistry  1992 267:15563-15567  PMID:1639796