recent publications
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academic article
- Ishikawa, T., Kono, D., Chung, J., Fowler, P., Theofilopoulos, A., Kakumu, S., Chisari, F. V. Polyclonality and multispecificity of the CTL response to a single viral epitope Journal of Immunology 1998 161:5842-5850 PMID:9834062
- Shimizu, Y., Guidotti, L. G., Fowler, P., Chisari, F. V. Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice Journal of Immunology 1998 161:4520-4529 PMID:9794377
- Nakamoto, Y., Guidotti, L. G., Kuhlen, C. V., Fowler, P., Chisari, F. V. Immune pathogenesis of hepatocellular carcinoma Journal of Experimental Medicine 1998 188:341-350 DOI:10.1084/jem.188.2.341 PMID:9670046
- Bertoni, R., Sidney, J., Fowler, P., Chesnut, R. W., Chisari, F. V., Sette, A. Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis Journal of Clinical Investigation 1997 100:503-513 DOI:10.1172/jci119559 PMID:9239396
- Tcheng, J. E., Lincoff, A. M., Sigmon, K. N., Lee, K. L., Kitt, M. M., Califf, R. M., Topol, E. J., Juran, N., Worley, S., Tuzi, J., Hollywood, L., Kleiman, N. S., et al. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT II Lancet 1997 349:1422-1428 PMID:9164315
- Rehermann, B., Fowler, P., Sidney, J., Person, J., Redeker, A., Brown, M., Moss, B., Sette, A., Chisari, F. V. The cytotoxic T-lymphocyte response to multiple hepatitis-B virus polymerase epitopes during and after acute viral-hepatitis Journal of Experimental Medicine 1995 181:1047-1058 DOI:10.1084/jem.181.3.1047 PMID:7532675
- Cerny, A., McHutchison, J. G., Pasquinelli, C., Brown, M. E., Brothers, M. A., Grabscheid, B., Fowler, P., Houghton, M., Chisari, F. V. Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif Journal of Clinical Investigation 1995 95:521-530 DOI:10.1172/jci117694 PMID:7860734 PMCID:PMC295505
- Cerny, A., Fowler, P., Brothers, M. A., Houghton, M., Schlicht, H. J., Chisari, F. V. Induction in vitro of a primary human antiviral cytotoxic T cell response European Journal of Immunology 1995 25:627-630 DOI:10.1002/eji.1830250248 PMID:7875224
- Hagen, T. M., Huang, S., Curnutte, J., Fowler, P., Martinez, V., Wehr, C. M., Ames, B. N., Chisari, F. V. Extensive oxidative DNA-damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular-carcinoma Proceedings of the National Academy of Sciences of the United States of America 1994 91:12808-12812 DOI:10.1073/pnas.91.26.12808 PMID:7809125
- Sette, A., Vitiello, A., Reherman, B., Fowler, P., Nayersina, R., Kast, W. M., Melief, C. J. M., Oseroff, C., Yuan, L., Ruppert, J., Sidney, J., Delguercio, M. F., et al. The relationship between class I binding affinity and immunogenicity of potential cytotoxic T cell epitopes Journal of Immunology 1994 153:5586-5592 PMID:7527444
- Huang, J. H., Getty, R. R., Chisari, F. V., Fowler, P., Greenspan, N. S., Tykocinski, M. L. Protein transfer of preformed MHC-peptide complexes sensitizes target cells to T cell cytolysis Immunity 1994 1:607-613 DOI:10.1016/1074-7613(94)90050-7 PMID:7600289
- Nayersina, R., Fowler, P., Guilhot, S., Missale, G., Cerny, A., Schlicht, H. J., Vitiello, A., Chesnut, R., Person, J. L., Redeker, A. G., Chisari, F. V. HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection Journal of Immunology 1993 150:4659-4671 PMID:7683326
- Bertoletti, A., Chisari, F. V., Penna, A., Guilhot, S., Galati, L., Missale, G., Fowler, P., Schlicht, H. J., Vitiello, A., Chesnut, R. C., Fiaccadori, F., Ferrari, C. Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein Journal of Virology 1993 67:2376-2380 PMID:7680391 PMCID:PMC240403
- Missale, G., Redeker, A., Person, J., Fowler, P., Guilhot, S., Schlicht, H. J., Ferrari, C., Chisari, F. V. HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis Journal of Experimental Medicine 1993 177:751-762 DOI:10.1084/jem.177.3.751 PMID:7679709
- Guilhot, S., Fowler, P., Portillo, G., Margolskee, R. F., Ferrari, C., Bertoletti, A., Chisari, F. V. Hepatitis B virus (HBV)-specific cytotoxic T-cell response in humans: production of target cells by stable expression of HBV-encoded proteins in immortalized human B-cell lines Journal of Virology 1992 66:2670-2678 PMID:1313893 PMCID:PMC241021
- Penna, A., Fowler, P., Bertoletti, A., Guilhot, S., Moss, B., Margolskee, R. F., Cavalli, A., Valli, A., Fiaccadori, F., Chisari, F. V., Ferrari, C. Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens Journal of Virology 1992 66:1193-1198 PMID:1731098 PMCID:PMC240825
- Penna, A., Bertoletti, A., Cavalli, A., Valli, A., Missale, G., Pilli, M., Marchelli, S., Giuberti, T., Fowler, P., Chisari, F. V., Fiaccadori, F., Ferrari, C. Fine specificity of the human T cell response to hepatitis B virus core antigen Archives of Virology 1992 23-28 PMID:1280506
- Penna, A., Chisari, F. V., Bertoletti, A., Missale, G., Fowler, P., Giuberti, T., Fiaccadori, F., Ferrari, C. Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen Journal of Experimental Medicine 1991 174:1565-1570 DOI:10.1084/jem.174.6.1565 PMID:1720813
- Bertoletti, A., Ferrari, C., Fiaccadori, F., Penna, A., Margolskee, R., Schlicht, H. J., Fowler, P., Guilhot, S., Chisari, F. V. HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen Proceedings of the National Academy of Sciences of the United States of America 1991 88:10445-10449 DOI:10.1073/pnas.88.23.10445 PMID:1660137
- Ferrari, C., Bertoletti, A., Penna, A., Cavalli, A., Valli, A., Missale, G., Pilli, M., Fowler, P., Giuberti, T., Chisari, F. V., Fiaccadori, F. Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen Journal of Clinical Investigation 1991 88:214-222 DOI:10.1172/jci115280 PMID:1711541