recent publications

• academic article

  • Cao, Y., Axup, J. Y., Ma, J. S. Y., Wang, R. E., Choi, S., Tardif, V., Lim, R. K. V., Pugh, H. M., Lawson, B. R., Welzel, G., Kazane, S. A., Sun, Y., et al. Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers Angewandte Chemie-International Edition  2015 54:7022-7027  DOI:10.1002/anie.201500799  PMID:25919418  PMCID:PMC4492699
  • Ramadoss, N. S., Schulman, A. D., Choi, S. H., Rodgers, D. T., Kazane, S. A., Kim, C. H., Lawson, B. R., Young, T. S. An anti-B cell maturation antigen bispecific antibody for multiple myeloma Journal of the American Chemical Society  2015 137:5288-5291  DOI:10.1021/jacs.5b01876  PMID:25826669
  • Kim, M. S., Ma, J. S. Y., Yun, H., Cao, Y., Kim, J. Y., Chi, V., Wang, D., Woods, A., Sherwood, L., Caballero, D., Gonzalez, J., Schultz, P. G., et al. Redirection of genetically engineered CAR-T cells using bifunctional small molecules Journal of the American Chemical Society  2015 137:2832-2835  DOI:10.1021/jacs.5b00106  PMID:25692571
  • Wang, R. E., Liu, T., Wang, Y., Cao, Y., Du, J., Luo, X., Deshmukh, V., Kim, C. H., Lawson, B. R., Tremblay, M. S., Young, T. S., Kazane, S. A., et al. An immunosuppressive antibody-drug conjugate Journal of the American Chemical Society  2015 137:3229-3232  DOI:10.1021/jacs.5b00620  PMID:25699419  PMCID:PMC4472444
  • Lu, H., Zhou, Q., Deshmukh, V., Phull, H., Ma, J., Tardif, V., Naik, R. R., Bouvard, C., Zhang, Y., Choi, S., Lawson, B. R., Zhu, S., et al. Targeting human C-type lectin-like molecule-1 (CLL1) with a bispecific antibody for immunotherapy of acute myeloid leukemia Angewandte Chemie-International Edition  2014 53:9841-9845  DOI:10.1002/anie.201405353  PMID:25056598  PMCID:PMC4280064
  • Sun, S. B., Schultz, P. G., Kim, C. H. Therapeutic applications of an expanded genetic code ChemBioChem  2014 15:1721-1729  DOI:10.1002/cbic.201402154  PMID:25044800  PMCID:PMC4472442
  • Furman, J. L., Kang, M. C., Choi, S., Cao, Y., Wold, E. D., Sun, S. B., Smider, V. V., Schultz, P. G., Kim, C. H. A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes Journal of the American Chemical Society  2014 136:8411-8417  DOI:10.1021/ja502851h  PMID:24846839  PMCID:PMC4227728
  • Kang, M., Light, K., Ai, H. W., Shen, W., Kim, C. H., Chen, P. R., Lee, H. S., Solomon, E. I., Schultz, P. G. Evolution of iron(II)-finger peptides by using a bipyridyl amino acid ChemBioChem  2014 15:822-825  DOI:10.1002/cbic.201300727  PMID:24591102  PMCID:PMC4010245
  • Meehan, T. F., Witherden, D. A., Kim, C. H., Sendaydiego, K., Ye, I., Garijo, O., Komori, H. K., Kumanogoh, A., Kikutani, H., Eckmann, L., Havran, W. L. Protection against colitis by CD100-dependent modulation of intraepithelial gamma delta T lymphocyte function Mucosal immunology  2014 7:134-142  DOI:10.1038/mi.2013.32  PMID:23695512  PMCID:PMC3795871
  • Kularatne, S. A., Deshmukh, V., Gymnopoulos, M., Biroc, S. L., Xia, J. M., Srinagesh, S., Sun, Y., Zou, N., Shimazu, M., Pinkstaff, J., Ensari, S., Knudsen, N., et al. Recruiting cytotoxic T cells to folate-receptor-positive cancer cells Angewandte Chemie-International Edition  2013 52:12101-12104  DOI:10.1002/anie.201306866  PMID:24573789  PMCID:PMC4012751
  • Kim, C. H., Axup, J. Y., Lawson, B. R., Yun, H., Tardif, V., Choi, S. H., Zhou, Q., Dubrovska, A., Biroc, S. L., Marsden, R., Pinstaff, J., Smider, V. V., et al. Bispecific small molecule-antibody conjugate targeting prostate cancer Proceedings of the National Academy of Sciences of the United States of America  2013 110:17796-17801  DOI:10.1073/pnas.1316026110  PMID:24127589  PMCID:PMC3816437
  • Kim, C. H., Axup, J. Y., Schultz, P. G. Protein conjugation with genetically encoded unnatural amino acids Current Opinion in Chemical Biology  2013 17:412-419  DOI:10.1016/j.cbpa.2013.04.017  PMID:23664497  PMCID:PMC4284959
  • Day, J. W., Kim, C. H., Smider, V. V., Schultz, P. G. Identification of metal ion binding peptides containing unnatural amino acids by phage display Bioorganic & Medicinal Chemistry Letters  2013  DOI:10.1016/j.bmcl.2013.02.106  PMID:23541674
  • Kazane, S. A., Axup, J. Y., Kim, C. H., Ciobanu, M., Wold, E. D., Barluenga, S., Hutchins, B. A., Schultz, P. G., Winssinger, N., Smider, V. V. Self-assembled antibody multimers through peptide nucleic acid conjugation Journal of the American Chemical Society  2013 135:340-346  DOI:10.1021/ja309505c  PMID:23210862  PMCID:PMC3951380
  • Axup, J. Y., Bajjuri, K. M., Ritland, M., Hutchins, B. M., Kim, C. H., Kazane, S. A., Halder, R., Forsyth, J. S., Santidrian, A. F., Stafin, K., Lu, Y. C., Tran, H., et al. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids Proceedings of the National Academy of Sciences of the United States of America  2012 109:16101-16106  DOI:10.1073/pnas.1211023109  PMID:22988081  PMCID:PMC3479532
  • Kim, C. H., Axup, J. Y., Dubrovska, A., Kazane, S. A., Hutchins, B. A., Wold, E. D., Smider, V. V., Schultz, P. G. Synthesis of bispecific antibodies using genetically encoded unnatural amino acids Journal of the American Chemical Society  2012 134:9918-9921  DOI:10.1021/ja303904e  PMID:22642368  PMCID:PMC4299457
  • Kim, C. H., Kang, M., Kim, H. J., Chatterjee, A., Schultz, P. G. Site-specific incorporation of ε-N-crotonyllysine into histones Angewandte Chemie-International Edition  2012 51:7246-7249  DOI:10.1002/anie.201203349  PMID:22689270  PMCID:PMC3783207
  • Hwang, J., Kim, Y., Kang, H. B., Jaroszewski, L., Deacon, A. M., Lee, H., Choi, W. C., Kim, K. J., Kim, C. H., Kang, B. S., Lee, J. O., Oh, T. K., et al. Crystal structure of the human n-myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor Journal of Biological Chemistry  2011 286  DOI:10.1074/jbc.M110.170803  PMID:21247902  PMCID:PMC3069448
  • Kim, C. H., Witherden, D. A., Havran, W. L. Characterization and TCR variable region gene use of mouse resident nasal gamma delta T lymphocytes Journal of Leukocyte Biology  2008 84:1259-1263  DOI:10.1189/jlb.0108050  PMID:18667688  PMCID:PMC2567898
  • Lee, H. K., Takamiya, K., Han, J. S., Man, H. Y., Kim, C. H., Rumbaugh, G., Yu, S., Ding, L., He, C., Petralia, R. S., Wenthold, R. J., Gallagher, M., et al. Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory Cell  2003 112:631-643  DOI:10.1016/s0092-8674(03)00122-3  PMID:12628184