recent publications
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academic article
- Bergum, P. W., Cruikshank, A., Maki, S. L., Kelly, C. R., Ruf, W., Vlasuk, G. P. Role of zymogen and activated factor x as scaffolds for the inhibition of the blood coagulation factor viia-tissue factor complex by recombinant nematode anticoagulant protein c2 Journal of Biological Chemistry 2001 276:10063-10071 DOI:10.1074/jbc.M009116200 PMID:11139576
- Donate, F., Kelly, C. R., Ruf, W., Edgington, T. S. Dimerization of tissue factor supports solution-phase autoactivation of factor vii without influencing proteolytic activation of factor x Biochemistry 2000 39:11467-11476 DOI:10.1021/bi000986p PMID:10985793
- Kelly, C. R., Dickinson, C. D., Ruf, W. Ca2+ binding to the first epidermal growth factor module of coagulation factor viia is important for cofactor interaction and proteolytic function Journal of Biological Chemistry 1997 272:17467-17472 DOI:10.1074/jbc.272.28.17467 PMID:9211891
- Dickinson, C. D., Kelly, C. R., Ruf, W. Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor viia Proceedings of the National Academy of Sciences of the United States of America 1996 93:14379-14384 DOI:10.1073/pnas.93.25.14379 PMID:8962059
- Kelly, C. R., Schullek, J. R., Ruf, W., Edgington, T. S. Tissue factor residue asp(44) regulates catalytic function of the bound proteinase factor vlla Biochemical Journal 1996 315:145-151 PMID:8670099 PMCID:PMC1217163
- Ruf, W., Kelly, C. R., Schullek, J. R., Martin, D. M. A., Polikarpov, I., Boys, C. W. G., Tuddenham, E. G. D., Edgington, T. S. Energetic contributions and topographical organization of ligand-binding residues of tissue factor Biochemistry 1995 34:6310-6315 DOI:10.1021/bi00019a008 PMID:7756258