recent publications

• academic article

  • Nicolaou, K. C., Lu, M., Totokotsopoulos, S., Heretsch, P., Giguere, D., Sun, Y. P., Sarlah, D., Nguyen, T. H., Wolf, I. C., Smee, D. F., Day, C. W., Bopp, S., et al. Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents Journal of the American Chemical Society  2012 134:17320-17332  DOI:10.1021/ja308429f  PMID:22978674  PMCID:PMC3490634
  • Chen, Z., Cheng, K., Walton, Z., Wang, Y. C., Ebi, H., Shimamura, T., Liu, Y., Tupper, T., Ouyang, J., Li, J., Gao, P., Woo, M. S., et al. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response Nature  2012 483:613-617  DOI:10.1038/nature10937  PMID:22425996  PMCID:PMC3385933
  • Nicolaou, K. C., Giguere, D., Totokotsopoulos, S., Sun, Y. P. A practical sulfenylation of 2,5-diketopiperazines Angewandte Chemie-International Edition  2012 51:728-732  DOI:10.1002/anie.201107623  PMID:22162254  PMCID:PMC3348727
  • Nicolaou, K. C., Sun, Y. P., Sarlah, D., Zhan, W. Q., Wu, T. R. Bioinspired synthesis of hirsutellones A, B, and C Organic Letters  2011 13:5708-5710  DOI:10.1021/ol202239u  PMID:21913732  PMCID:PMC3207260
  • Nicolaou, K. C., Totokotsopoulos, S., Giguere, D., Sun, Y. P., Sarlah, D. Total synthesis of epicoccin G Journal of the American Chemical Society  2011 133:8150-8153  DOI:10.1021/ja2032635  PMID:21548595  PMCID:PMC3102137
  • Nicolaou, K. C., Sun, Y. P., Korman, H., Sarlah, D. Asymmetric total synthesis of cylindrocyclophanes A and F through cyclodimerization and a Ramberg-Bäcklund reaction Angewandte Chemie-International Edition  2010 49:5875-5878  DOI:10.1002/anie.201003500  PMID:20623817  PMCID:PMC3014728
  • Nicolaou, K. C., Peng, X. S., Sun, Y. P., Polet, D., Zou, B., Lim, C. S., Chen, D. Y. K. Total synthesis and biological evaluation of cortistatins a and j and analogues thereof Journal of the American Chemical Society  2009 131:10587-10597  DOI:10.1021/ja902939t  PMID:19722632
  • Nicolaou, K. C., Leung, G. Y. C., Dethe, D. H., Guduru, R., Sun, Y. P., Lim, C. S., Chen, D. Y. K. Chemical synthesis and biological evaluation of palmerolide a analogues Journal of the American Chemical Society  2008 130:10019-10023  DOI:10.1021/ja802803e  PMID:18598030
  • Nicolaou, K. C., Sun, Y. P., Guduru, R., Banerji, B., Chen, D. Y. K. Total synthesis of the originally proposed and revised structures of palmerolide a and isomers thereof Journal of the American Chemical Society  2008 130:3633-3644  DOI:10.1021/ja710485n  PMID:18298117
  • Nicolaou, K. C., Sun, Y. P., Peng, X. S., Polet, D., Chen, D. Y. K. Total synthesis of (+)-cortistatin a Angewandte Chemie-International Edition  2008 47:7310-7313  DOI:10.1002/anie.200803550  PMID:18704899
  • Nicolaou, K. C., Guduru, R., Sun, Y. P., Banerji, B., Chen, D. Y. K. Total synthesis of the originally proposed and revised structures of palmerolide a Angewandte Chemie-International Edition  2007 46:5896-5900  DOI:10.1002/anie.200702243  PMID:17600809