recent publications
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academic article
- Nicolaou, K. C., Lu, M., Totokotsopoulos, S., Heretsch, P., Giguere, D., Sun, Y. P., Sarlah, D., Nguyen, T. H., Wolf, I. C., Smee, D. F., Day, C. W., Bopp, S., et al. Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents Journal of the American Chemical Society 2012 134:17320-17332 DOI:10.1021/ja308429f PMID:22978674 PMCID:PMC3490634
- Chen, Z., Cheng, K., Walton, Z., Wang, Y. C., Ebi, H., Shimamura, T., Liu, Y., Tupper, T., Ouyang, J., Li, J., Gao, P., Woo, M. S., et al. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response Nature 2012 483:613-617 DOI:10.1038/nature10937 PMID:22425996 PMCID:PMC3385933
- Nicolaou, K. C., Giguere, D., Totokotsopoulos, S., Sun, Y. P. A practical sulfenylation of 2,5-diketopiperazines Angewandte Chemie-International Edition 2012 51:728-732 DOI:10.1002/anie.201107623 PMID:22162254 PMCID:PMC3348727
- Nicolaou, K. C., Sun, Y. P., Sarlah, D., Zhan, W. Q., Wu, T. R. Bioinspired synthesis of hirsutellones A, B, and C Organic Letters 2011 13:5708-5710 DOI:10.1021/ol202239u PMID:21913732 PMCID:PMC3207260
- Nicolaou, K. C., Totokotsopoulos, S., Giguere, D., Sun, Y. P., Sarlah, D. Total synthesis of epicoccin G Journal of the American Chemical Society 2011 133:8150-8153 DOI:10.1021/ja2032635 PMID:21548595 PMCID:PMC3102137
- Nicolaou, K. C., Sun, Y. P., Korman, H., Sarlah, D. Asymmetric total synthesis of cylindrocyclophanes A and F through cyclodimerization and a Ramberg-Bäcklund reaction Angewandte Chemie-International Edition 2010 49:5875-5878 DOI:10.1002/anie.201003500 PMID:20623817 PMCID:PMC3014728
- Nicolaou, K. C., Peng, X. S., Sun, Y. P., Polet, D., Zou, B., Lim, C. S., Chen, D. Y. K. Total synthesis and biological evaluation of cortistatins a and j and analogues thereof Journal of the American Chemical Society 2009 131:10587-10597 DOI:10.1021/ja902939t PMID:19722632
- Nicolaou, K. C., Leung, G. Y. C., Dethe, D. H., Guduru, R., Sun, Y. P., Lim, C. S., Chen, D. Y. K. Chemical synthesis and biological evaluation of palmerolide a analogues Journal of the American Chemical Society 2008 130:10019-10023 DOI:10.1021/ja802803e PMID:18598030
- Nicolaou, K. C., Sun, Y. P., Guduru, R., Banerji, B., Chen, D. Y. K. Total synthesis of the originally proposed and revised structures of palmerolide a and isomers thereof Journal of the American Chemical Society 2008 130:3633-3644 DOI:10.1021/ja710485n PMID:18298117
- Nicolaou, K. C., Sun, Y. P., Peng, X. S., Polet, D., Chen, D. Y. K. Total synthesis of (+)-cortistatin a Angewandte Chemie-International Edition 2008 47:7310-7313 DOI:10.1002/anie.200803550 PMID:18704899
- Nicolaou, K. C., Guduru, R., Sun, Y. P., Banerji, B., Chen, D. Y. K. Total synthesis of the originally proposed and revised structures of palmerolide a Angewandte Chemie-International Edition 2007 46:5896-5900 DOI:10.1002/anie.200702243 PMID:17600809