recent publications

• academic article

  • Shen, G. Q., Girelli, D., Li, L., Rao, S., Archacki, S., Olivieri, O., Martinelli, N., Park, J. E., Chen, Q., Topol, E. J., Wang, Q. K. A novel molecular diagnostic marker for familial and early-onset coronary artery disease and myocardial infarction in the LRP8 gene Circulation-Cardiovascular Genetics  2014 7:514-520  DOI:10.1161/circgenetics.113.000321  PMID:24867879  PMCID:PMC4140990
  • Shen, G. Q., Girelli, D., Li, L., Olivieri, O., Martinelli, N., Chen, Q., Topol, E. J., Wang, Q. K. Multi-allelic haplotype association identifies novel information different from single-SNP analysis: A new protective haplotype in the LRP8 gene is against familial and early-onset CAD and MI Gene  2013 521:78-81  DOI:10.1016/j.gene.2013.03.022  PMID:23524007  PMCID:PMC3919654
  • Yang, R., Li, L., Seidelmann, S. B., Shen, G. Q., Sharma, S., Rao, S. Q., Abdullah, K. G., MacKinlay, K. G., Elston, R. C., Chen, Q. Y., Topol, E. J., Wang, Q. K. A genome-wide linkage scan identifies multiple quantitative trait loci for hdl-cholesterol levels in families with premature cad and mi Journal of Lipid Research  2010 51:1442-1451  DOI:10.1194/jlr.M004325  PMID:20075193  PMCID:PMC3035507
  • Abdullah, K. G., Li, L., Shen, G. Q., Hu, Y., Yang, Y., MacKinlay, K. G., Topol, E. J., Wang, Q. K. Four snps on chromosome 9p21 confer risk to premature, familial cad and mi in an american caucasian population (genequest) Annals of Human Genetics  2008 72:654-657  DOI:10.1111/j.1469-1809.2008.00454.x  PMID:18505420  PMCID:PMC2634771
  • Seidelmann, S. B., Li, L., Shen, G. Q., Topol, E. J., Wang, Q. K. Identification of a novel locus for triglyceride on chromosome 1p31-32 in families with premature cad and mi Journal of Lipid Research  2008 49:1034-1038  DOI:10.1194/jlr.M700576-JLR200  PMID:18245017  PMCID:PMC2311437
  • Shen, G. Q., Li, L., Girelli, D., Seidelmann, S. B., Rao, S., Fan, C., Park, J. E., Xi, Q., Li, J., Hu, Y., Olivieri, O., Marchant, K., et al. An lrp8 variant is associated with familial and premature coronary artery disease and myocardial infarction American Journal of Human Genetics  2007 81:780-791  DOI:10.1086/521581  PMID:17847002  PMCID:PMC2227927
  • Bhagavatula, M. R. K., Fan, C., Shen, G. Q., Cassano, J., Plow, E. F., Topol, E. J., Wang, Q. Transcription factor mef2a mutations in patients with coronary artery disease Human Molecular Genetics  2004 13:3181-3188  DOI:10.1093/hmg/ddh329  PMID:15496429  PMCID:PMC1579761
  • Wang, Q., Rao, S. Q., Shen, G. Q., Li, L., Moliterno, D. J., Newby, L. K., Rogers, W. J., Cannata, R., Zirzow, E., Elston, R. C., Topol, E. J. Premature myocardial infarction novel susceptibility locus on chromosome 1p34-36 identified by genomewide linkage analysis American Journal of Human Genetics  2004 74:262-271  DOI:10.1086/381560  PMID:14732905  PMCID:PMC1181924
  • Rao, S. Q., Li, L., Li, X., Moser, K. L., Guo, Z., Shen, G. Q., Cannata, R., Zirzow, E., Topol, E. J., Wang, Q. Genetic linkage analysis of longitudinal hypertension phenotypes using three summary measures BMC Genetics  2003 4:S24  DOI:10.1186/1471-2156-4-s1-s24  PMID:14975092
  • Guo, Z., Li, X., Rao, S. Q., Moser, K. L., Zhang, T. W., Gong, B. S., Shen, G. Q., Li, L., Cannata, R., Zirzow, E., Topol, E. J., Wang, Q. Multivariate sib-pair linkage analysis of longitudinal phenotypes by three step-wise analysis approaches BMC Genetics  2003 4:S68  DOI:10.1186/1471-2156-4-s1-s68  PMID:14975136
  • Archacki, S. R., Angheloiu, G., Tian, X. L., Tan, F. L., DiPaola, N., Shen, G. Q., Moravec, C., Ellis, S., Topol, E. J., Wang, Q. Identification of new genes differentially expressed in coronary artery disease by expression profiling Physiological Genomics  2003 15:65-74  DOI:10.1152/physiolgenomics.00181.2002  PMID:12902549