recent publications

• academic article

  • Keller, T. L., Zocco, D., Sundrud, M. S., Hendrick, M., Edenius, M., Yum, J., Kim, Y. J., Lee, H. K., Cortese, J. F., Wirth, D. F., Dignam, J. D., Rao, A., et al. Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase Nature Chemical Biology  2012 8:311-317  DOI:10.1038/nchembio.790  PMID:22327401  PMCID:PMC3281520
  • Kwon, S. H., Lee, H. K., Kim, J. A., Hong, S. I., Kim, S. Y., Jo, T. H., Park, Y. I., Lee, C. K., Kim, Y. B., Lee, S. Y., Jang, C. G. Neuroprotective effects of eucommia ulmoides oliv. Bark on amyloid beta(25-35)-induced learning and memory impairments in mice Neuroscience Letters  2011 487:123-127  DOI:10.1016/j.neulet.2010.10.042  PMID:20974223
  • Yoo, J. H., Lee, H. K., Kim, H. C., Lee, S. Y., Jang, C. G. Gaba(a) receptors mediate the attenuating effects of a 5-ht(3) receptor antagonist on methamphetamine-induced behavioral sensitization in mice Synapse  2010 64:274-279  DOI:10.1002/syn.20726  PMID:19953653
  • Kwon, S. H., Lee, H. K., Kim, J. A., Hong, S. I., Kim, H. C., Jo, T. H., Park, Y. I., Lee, C. K., Kim, Y. B., Lee, S. Y., Jang, C. G. Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice European Journal of Pharmacology  2010 649:210-217  DOI:10.1016/j.ejphar.2010.09.001  PMID:20854806
  • Astronomo, R. D., Lee, H. K., Scanlan, C. N., Pantophlet, R., Huang, C. Y., Wilson, I. A., Blixt, O., Dwek, R. A., Wong, C. H., Burton, D. R. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2g12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120 Journal of Virology  2008 82:6359-6368  DOI:10.1128/jvi.00293-08  PMID:18434393  PMCID:PMC2447108
  • Lee, H. K., Brown, S. J., Rosen, H., Tobias, P. S. Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors Molecular Pharmacology  2007 72:868-875  DOI:10.1124/mol.107.038349  PMID:17615244
  • Lee, H. K., Dunzendorfer, S., Soldau, K., Tobias, P. S. Double-stranded rna-mediated tlr3 activation is enhanced by cd14 Immunity  2006 24:153-163  DOI:10.1016/j.immuni.2005.12.012  PMID:16473828
  • Calarese, D. A., Lee, H. K., Huang, C. Y., Best, M. D., Astronomo, R. D., Stanfield, R. L., Katinger, H., Burton, D. R., Wong, C. H., Wilson, I. A. Dissection of the carbohydrate specificity of the broadly neutralizing-anti-hiv-1 antibody 2g12 Proceedings of the National Academy of Sciences of the United States of America  2005 102:13372-13377  DOI:10.1073/pnas.0505763102  PMID:16174734  PMCID:PMC1224641
  • Fazio, F., Bryan, M. C., Lee, H. K., Chang, A., Wong, C. H. Assembly of sugars on polystyrene plates: A new facile microarray fabrication technique Tetrahedron Letters  2004 45:2689-2692  DOI:10.1016/j.tetlet.2004.01.159
  • Bryan, M. C., Fazio, F., Lee, H. K., Huang, C. Y., Chang, A., Best, M. D., Calarese, D. A., Blixt, C., Paulson, J. C., Burton, D., Wilson, I. A., Wong, C. H. Covalent display of oligosaccharide arrays in microtiter plates Journal of the American Chemical Society  2004 126:8640-8641  DOI:10.1021/ja048433f  PMID:15250702
  • Lee, H. K., Dunzendorfer, S., Tobias, P. S. Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation Journal of Biological Chemistry  2004 279:10564-10574  DOI:10.1074/jbc.M311564200  PMID:14699116
  • Dunzendorfer, S., Lee, H. K., Tobias, P. S. Flow-dependent regulation of endothelial toll-like receptor 2 expression through inhibition of sp1 activity Circulation Research  2004 95:684-691  DOI:10.1161/01.res.0000143900.19798.47  PMID:15345653
  • Lee, H. K., Scanlan, C. N., Huang, C. Y., Chang, A. Y., Calarese, D. A., Dwek, R. A., Rudd, P. M., Burton, D. R., Wilson, I. A., Wong, C. H. Reactivity-based one-pot synthesis of oligomannoses: Defining antigens recognized by 2g12, a broadly neutralizing anti-hiv-1 antibody Angewandte Chemie-International Edition  2004 43:1000-1003  DOI:10.1002/anie.200353105  PMID:14966891
  • Dunzendorfer, S., Lee, H. K., Soldau, K., Tobias, P. S. Tlr4 is the signaling but not the lipopolysaccharide uptake receptor Journal of Immunology  2004 173:1166-1170  PMID:15240706
  • Dunzendorfer, S., Lee, H. K., Soldau, K., Tobias, P. S. Toll-like receptor 4 functions intracellularly in human coronary artery endothelial cells: Roles of lbp and scd14 in mediating lps-responses FASEB Journal  2004 18:1117-1119  DOI:10.1096/fj.03-1263fje  PMID:15132988
  • Lee, H. K., Takamiya, K., Han, J. S., Man, H. Y., Kim, C. H., Rumbaugh, G., Yu, S., Ding, L., He, C., Petralia, R. S., Wenthold, R. J., Gallagher, M., et al. Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory Cell  2003 112:631-643  DOI:10.1016/s0092-8674(03)00122-3  PMID:12628184
  • Mong, T. K. K., Lee, H. K., Duron, S. G., Wong, C. H. Reactivity-based one-pot total synthesis of fucose gm(1) oligosaccharide: A sialylated antigenic epitope of small-cell lung cancer Proceedings of the National Academy of Sciences of the United States of America  2003 100:797-802  DOI:10.1073/pnas.0337590100  PMID:12552090  PMCID:PMC298681
  • Jang, C. G., Lee, S. Y., Lee, H. K., Suh, H. W., Song, D. K. Time courses of pcreb expression after dopaminergic stimulation by apomorphine in mouse brain Archives of Pharmacal Research  2002 25:370-374  DOI:10.1007/bf02976641  PMID:12135112
  • Lee, H. K., Lee, J., Tobias, P. S. Two lipoproteins extracted from escherichia coli k-12 lcd25 lipopolysaccharide are the major components responsible for toll-like receptor 2-mediated signaling Journal of Immunology  2002 168:4012-4017  PMID:11937558
  • Tobias, P. S., Lee, H. K., Orr, S., Soldau, K., Tapping, R. Innate immune system recognition of microbial pathogens Immunologic Research  2000 21:341-343  DOI:10.1385/ir:21:2-3:341  PMID:10852135