recent publications
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academic article
- Wieskopf, J. S., Mathur, J., Limapichat, W., Post, M. R., Al-Qazzaz, M., Sorge, R. E., Martin, L. J., Zaykin, D. V., Smith, S. B., Freitas, K., Austin, J. S., Dai, F., et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors Science Translational Medicine 2015 7:287ra72 DOI:10.1126/scitranslmed.3009986 PMID:25972004 PMCID:PMC5018401
- Shanmugam, A., Wang, J., Markand, S., Perry, R. L., Tawfik, A., Zorrilla, E., Ganapathy, V., Smith, S. B. Sigma receptor 1 activation attenuates release of inflammatory cytokines MIP1 gamma, MIP2, MIP3 alpha, and IL12 (p40/p70) by retinal Muller glial cells Journal of Neurochemistry 2015 132:546-558 DOI:10.1111/jnc.13002 PMID:25439327 PMCID:PMC4451448
- Wang, J., Shanmugam, A., Markand, S., Zorrilla, E., Ganapathy, V., Smith, S. B. Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger Free Radical Biology and Medicine 2015 86:25-36 DOI:10.1016/j.freeradbiomed.2015.04.009 PMID:25920363 PMCID:PMC4554890
- Ha, Y. J., Shanmugam, A. K., Markand, S., Zorrilla, E., Ganapathy, V., Smith, S. B. Sigma receptor 1 modulates ER stress and Bcl2 in murine retina Cell and Tissue Research 2014 356:15-27 DOI:10.1007/s00441-013-1774-8 PMID:24469320 PMCID:PMC3976706
- Ha, Y. J., Saul, A., Tawfik, A., Zorrilla, E. P., Ganapathy, V., Smith, S. B. Diabetes accelerates retinal ganglion cell dysfunction in mice lacking sigma receptor 1 Molecular Vision 2012 18:2860-2870 PMID:23233788 PMCID:PMC3519370
- Ha, Y. J., Saul, A., Tawfik, A., Williams, C., Bollinger, K., Smith, R., Tachikawa, M., Zorrilla, E., Ganapathy, V., Smith, S. B. Late-onset inner retinal dysfunction in mice lacking sigma receptor 1 (sigma r1) Investigative Ophthalmology & Visual Science 2011 52:7749-7760 DOI:10.1167/iovs.11-8169 PMID:21862648 PMCID:PMC3183986