recent publications

• academic article

  • Bystrykh, L., Weersing, E., Dontje, B., Sutton, S., Pletcher, M. T., Wiltshire, T., Su, A. I., Vellenga, E., Wang, J. T., Manly, K. F., Lu, L., Chesler, E. J., et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' Nature Genetics  2005 37:225-232  DOI:10.1038/ng1497  PMID:15711547
  • Ma, L. L., Qian, S. G., Liang, X. Y., Wang, L. F., Woodward, J. E., Giannoukakis, N., Robbins, P. D., Bertera, S., Trucco, M., Fung, J. J., Lu, L. Prevention of diabetes in NOD nice by administration of dendritic cells deficient in nuclear transcription factor-kappa B activity Diabetes  2003 52:1976-1985  DOI:10.2337/diabetes.52.8.1976  PMID:12882913
  • Bonham, C. A., Peng, L. S., Liang, X. Y., Chen, Z. Y., Wang, L. F., Ma, L. L., Hackstein, H., Robbins, P. D., Thomson, A. W., Fung, J. J., Qian, S. G., Lu, L. Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-kappa B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-lg Journal of Immunology  2002 169:3382-3391  PMID:12218160
  • Whalen, J. D., Thomson, A. W., Lu, L., Robbins, P. D., Evans, C. H. Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: Evidence for involvement of genetically modified dendritic cells and macrophages Molecular Therapy  2001 4:543-550  DOI:10.1006/mthe.2001.0492  PMID:11735338
  • Hsu, D. K., Yang, R. Y., Pan, Z. X., Lu, L., Salomon, D. R., Fung-Leung, W. P., Liu, F. T. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses American Journal of Pathology  2000 156:1073-1083  DOI:10.1016/s0002-9440(10)64975-9  PMID:10702423
  • Giannoukakis, N., Bonham, C. A., Qian, S. G., Zhou, Z. Y., Peng, L., Harnaha, J., Li, W., Thomson, A. W., Fung, J. J., Robbins, P. D., Lu, L. Prolongation of cardiac allograft survival using dendritic cells treated with NF-kappa B decoy oligodeoxyribonucleotides Molecular Therapy  2000 1:430-437  DOI:10.1006/mthe.2000.0060  PMID:10933964
  • Lu, L., Gambotto, A., Lee, W. C., Qian, S., Bonham, C. A., Robbins, P. D., Thomson, A. W. Adenoviral delivery of CTLA4ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients Gene Therapy  1999 6:554-563  DOI:10.1038/sj.gt.3300862  PMID:10476215
  • Lu, L., Lee, W. C., Gambotto, A., Zhong, C., Robbins, P. D., Qian, S., Fung, J. J., Thomson, A. W. Transduction of dendritic cells with adenoviral vectors encoding ctla4-ig markedly reduces their allostimulatory activity Transplantation Proceedings  1999 31:797-797  DOI:10.1016/s0041-1345(98)01774-6  PMID:10083343
  • Lu, L., Lee, W. C., Takayama, T., Qian, S. G., Gambotto, A., Robbins, P. D., Thomson, A. W. Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL-10, TGF-beta, and CTLA4lg) Journal of Leukocyte Biology  1999 66:293-296  PMID:10449170
  • Lee, W. C., Zhong, C., Qian, S., Wan, Y., Gauldie, J., Mi, Z., Robbins, P. D., Thomson, A. W., Lu, L. Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta Transplantation  1998 66:1810-1817  DOI:10.1097/00007890-199812270-00040  PMID:9884280