recent publications

• academic article

  • Wu, W. Y., Luo, Y. P., Sun, C. Z., Liu, Y. A., Kuo, P., Varga, J., Xiang, R., Reisfeld, R., Janda, K. D., Edgington, T. S., Liu, C. Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms Cancer Research  2006 66:970-980  DOI:10.1158/0008-5472.can-05-2591  PMID:16424032
  • Kaufmann, G. F., Meijler, M. M., Sun, C. Z., Chen, D. W., Kujawa, D. P., Mee, J. M., Hoffman, T. Z., Wirsching, P., Lerner, R. A., Janda, K. D. Enzymatic incorporation of an antibody-activated blue fluorophore into DNA Angewandte Chemie-International Edition  2005 44:2144-2148  DOI:10.1002/anie.200461143  PMID:15742317
  • Lillo, A. M., Sun, C. Z., Gao, C., Ditzel, H., Parrish, J., Gauss, C. M., Moss, J., Felding-Habermann, B., Wirsching, P., Boger, D. L., Janda, K. D. A human single-chain antibody specific for integrin alpha(3)beta(1) capable of cell internalization and delivery of antitumor agents Chemistry & Biology  2004 11:897-906  DOI:10.1016/j.chembiol.2004.04.018  PMID:15271348
  • Qi, L. W., Meijler, M. M., Lee, S. H., Sun, C. Z., Janda, K. D. Solid-phase synthesis of anandamide analogues Organic Letters  2004 6:1673-1675  DOI:10.1021/ol049474j  PMID:15128264
  • Meijler, M. M., Hom, L. G., Kaufmann, G. F., McKenzie, K. M., Sun, C. Z., Moss, J. A., Matsushita, M., Janda, K. D. Synthesis and biological validation of a ubiquitous quorum-sensing molecule Angewandte Chemie-International Edition  2004 43:2106-2108  DOI:10.1002/anie.200353150  PMID:15083457
  • Sun, C. Z., Wirsching, P., Janda, K. D. Enabling ScFvs as multi-drug carriers: A dendritic approach Bioorganic & Medicinal Chemistry  2003 11:1761-1768  DOI:10.1016/s0968-0896(03)00057-9  PMID:12659762
  • Liu, C., Sun, C. Z., Huang, H. N., Janda, K., Edgington, T. Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy Cancer Research  2003 63:2957-2964  PMID:12782603
  • Lee, K. J., Mao, S. L., Sun, C. Z., Gao, C., Blixt, O., Arrues, S., Hom, L. G., Kaufmann, G. F., Hoffman, T. Z., Coyle, A. R., Paulson, J., Felding-Habermann, B., et al. Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen Journal of the American Chemical Society  2002 124:12439-12446  DOI:10.1021/ja020737j  PMID:12381184
  • Sun, C. Z., Wirsching, P., Janda, K. D. Syntheses of dendritic linkers containing chlorambucil residues for the preparation of antibody-multidrug immunoconjugates Bioorganic & Medicinal Chemistry Letters  2002 12:2213-2215  DOI:10.1016/s0960-894x(02)00361-x  PMID:12127540