recent publications

• academic article

  • Schnecke, V., Swanson, C. A., Getzoff, E. D., Tainer, J. A., Kuhn, L. A. Screening a peptidyl database for potential ligands to proteins with side-chain flexibility Proteins-Structure Function and Genetics  1998 33:74-87  DOI:10.1002/(sici)1097-0134(19981001)33:1<74::aid-prot7>3.0.co;2-l  PMID:9741846
  • Pond, L., Kuhn, L. A., Teyton, L., Schutze, M. P., Tainer, J. A., Jackson, M. R., Peterson, P. A. A role for acidic residues in di-leucine motif-based targeting to the endocytic pathway Journal of Biological Chemistry  1995 270:19989-19997  PMID:7650016
  • Kuhn, L. A., Swanson, C. A., Pique, M. E., Tainer, J. A., Getzoff, E. D. Atomic and residue hydrophilicity in the context of folded protein structures Proteins-Structure Function and Genetics  1995 23:536-547  DOI:10.1002/prot.340230408  PMID:8749849
  • Chang, C. P., Lazar, C. S., Walsh, B. J., Komuro, M., Collawn, J. F., Kuhn, L. A., Tainer, J. A., Trowbridge, I. S., Farquhar, M. G., Rosenfeld, M. G., Wiley, H. S., Gill, G. N. Ligand-induced internalization of the epidermal growth-factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors Journal of Biological Chemistry  1993 268:19312-19320  PMID:8396132
  • Boissinot, M., Kuhn, L. A., Lee, P., Fisher, C. L., Wang, Y., Hallewell, R. A., Tainer, J. A. Rational design and expression of a heparin-targeted human superoxide-dismutase Biochemical and Biophysical Research Communications  1993 190:250-256  DOI:10.1006/bbrc.1993.1038  PMID:8422249
  • Kuhn, L. A., Siani, M. A., Pique, M. E., Fisher, C. L., Getzoff, E. D., Tainer, J. A. The interdependence of protein surface-topography and bound water-molecules revealed by surface accessibility and fractal density measures Journal of Molecular Biology  1992 228:13-22  DOI:10.1016/0022-2836(92)90487-5  PMID:1447777
  • Collawn, J. F., Kuhn, L. A., Liu, L. F. S., Tainer, J. A., Trowbridge, I. S. Transplanted ldl and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor EMBO Journal  1991 10:3247-3253  PMID:1655415  PMCID:PMC453049
  • Kuhn, L. A., Griffin, J. H., Fisher, C. L., Greengard, J. S., Bouma, B. N., Espana, F., Tainer, J. A. Elucidating the structural chemistry of glycosaminoglycan recognition by protein-C inhibitor Proceedings of the National Academy of Sciences of the United States of America  1990 87:8506-8510  DOI:10.1073/pnas.87.21.8506  PMID:2172989
  • Collawn, J. F., Stangel, M., Kuhn, L. A., Esekogwu, V., Jing, S. Q., Trowbridge, I. S., Tainer, J. A. Transferrin receptor internalization sequence yxrf implicates a tight turn as the structural recognition motif for endocytosis Cell  1990 63:1061-1072  DOI:10.1016/0092-8674(90)90509-d  PMID:2257624