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Solution-phase generation of tetraurea libraries

Academic Article
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Overview

authors

  • Shipps, G. W.
  • Spitz, U. P.
  • Rebek Jr., Julius

publication date

  • May 1996

journal

  • Bioorganic & Medicinal Chemistry  Journal

abstract

  • Libraries of tetraureas tethered to a rigid core have been assembled. This simple, solution-phase methodology generates a defined, anticipated distribution of compounds. These conclusions are supported by synthesizing pure (homo) tetraurea xanthenes and by HPLC analysis of small 'microlibraries'.

subject areas

  • Chromatography, High Pressure Liquid
  • Solutions
  • Urea
  • Xanthenes
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Identity

International Standard Serial Number (ISSN)

  • 0968-0896

Digital Object Identifier (DOI)

  • 10.1016/0968-0896(96)00059-4

PubMed ID

  • 8804529
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Additional Document Info

start page

  • 655

end page

  • 657

volume

  • 4

issue

  • 5

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