Solution-phase generation of tetraurea libraries

Academic Article

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Overview

authors

• Shipps, G. W.
• Spitz, U. P.
• Rebek Jr., Julius

publication date

• May 1996

journal

• Bioorganic & Medicinal Chemistry  Journal

abstract

• Libraries of tetraureas tethered to a rigid core have been assembled. This simple, solution-phase methodology generates a defined, anticipated distribution of compounds. These conclusions are supported by synthesizing pure (homo) tetraurea xanthenes and by HPLC analysis of small 'microlibraries'.

subject areas

• Chromatography, High Pressure Liquid
• Solutions
• Urea
• Xanthenes

Identity

International Standard Serial Number (ISSN)

• 0968-0896

Digital Object Identifier (DOI)

• 10.1016/0968-0896(96)00059-4

PubMed ID

• 8804529

Additional Document Info

start page

• 655

end page

• 657

volume

• 4

issue

• 5