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Structural basis for a disfavored elimination reaction in catalytic antibody 1D4

Academic Article
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Overview

related to degree

  • Larsen, Nicholas, Ph.D. in Biology, Scripps Research 1998 - 2002

authors

  • Larsen, Nicholas
  • Heine, A.
  • Crane, L.
  • Cravatt, Benjamin
  • Lerner, Richard
  • Wilson, Ian

publication date

  • November 2001

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Animals
  • Antibodies, Catalytic
  • Binding Sites, Antibody
  • Catalysis
  • Cations
  • Crystallography, X-Ray
  • Entropy
  • Haptens
  • Hydrogen Bonding
  • Immunoglobulin Fab Fragments
  • Immunoglobulin G
  • Ligands
  • Mice
  • Models, Molecular
  • Protein Conformation
  • Solvents
  • Static Electricity
  • Structure-Activity Relationship
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Research

keywords

  • catalytic antibody
  • crystal structure
  • disfavored chemistry
  • syn-elimination reaction
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.2001.5112

PubMed ID

  • 11724535
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Additional Document Info

start page

  • 93

end page

  • 102

volume

  • 314

issue

  • 1

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