related to degree

• Tse, Winston, Ph.D. in Chemistry, Scripps Research 1998 - 2003

authors

• Tse, Winston
• Boger, Dale

publication date

• December 2004

journal

• Chemistry & Biology  Journal

abstract

• Biologically active, therapeutically useful, DNA binding natural products continue to reveal new paradigms for sequence-selective recognition, to enlist beautiful mechanisms of in situ activation for DNA modification, to define new therapeutic targets, to exploit new mechanisms to achieve cellular selectivity, and to provide a rich source of new drugs. These attributes arise in compact structures of complex integrated function.

subject areas

• Animals
• Antineoplastic Agents
• DNA
• Humans
• Models, Molecular
• Molecular Conformation
• Protein Binding
• Stereoisomerism
• Structure-Activity Relationship
• Substrate Specificity

International Standard Serial Number (ISSN)

• 1074-5521

Digital Object Identifier (DOI)

• 10.1016/j.chembiol.2003.08.012

PubMed ID

• 15610844

start page

• 1607

end page

• 1617

volume

• 11

issue

• 12