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Phagocytosis and development: back to the future

Academic Article
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Overview

authors

  • Franc, Nathalie
  • White, K.
  • Ezekowitz, R. A. B.

publication date

  • February 1999

journal

  • Current Opinion in Immunology  Journal

abstract

  • Removal of apoptotic cells and micro-organisms is mediated via phagocytosis. Phagocytes express pattern-recognition receptors (PRRs) that recognize apoptotic-cell-associated membrane patterns (ACAMPs). Similar ACAMPs and PRRs are used by mammals, Caenorhabditis elegans and Drosophila melanogaster. Some PRRs recognize apoptotic cells and micro-organisms, suggesting overlap between these functions.

subject areas

  • Animals
  • Caenorhabditis elegans
  • Drosophila melanogaster
  • Humans
  • Macrophages
  • Mammals
  • Phagocytosis
  • Receptors, Immunologic
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Identity

International Standard Serial Number (ISSN)

  • 0952-7915

Digital Object Identifier (DOI)

  • 10.1016/s0952-7915(99)80009-0

PubMed ID

  • 10047544
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Additional Document Info

start page

  • 47

end page

  • 52

volume

  • 11

issue

  • 1

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