recent publications

• academic article

  • Dosenovic, P., von Boehmer, L., Escolano, A., Jardine, J., Freund, N. T., Gitlin, A. D., McGuire, A. T., Kulp, D. W., Oliveira, T., Scharf, L., Pietzsch, J., Gray, M. D., et al. Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice Cell  2015 161:1505-1515  DOI:10.1016/j.cell.2015.06.003  PMID:26091035  PMCID:PMC4604566
  • Zhou, T., Lynch, R. M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N. A., Joyce, M. G., Lingwood, D., Soto, C., Bailer, R. T., Ernandes, M. J., Kong, R., et al. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Cell  2015 161:1280-1292  DOI:10.1016/j.cell.2015.05.007  PMID:26004070  PMCID:PMC4683157
  • Jardine, J., Julien, J. P., Menis, S., Ota, T., Kalyuzhniy, O., McGuire, A., Sok, D., Huang, P. S., MacPherson, S., Jones, M., Nieusma, T., Mathison, J., et al. Rational HIV immunogen design to target specific germline B cell receptors Science  2013 340:711-716  DOI:10.1126/science.1234150  PMID:23539181  PMCID:PMC3689846
  • McGuire, A. T., Hoot, S., Dreyer, A. M., Lippy, A., Stuart, A., Cohen, K. W., Jardine, J., Menis, S., Scheid, J. F., West, A. P., Schief, W. R., Stamatatos, L. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies Journal of Experimental Medicine  2013 210:655-663  DOI:10.1084/jem.20122824  PMID:23530120  PMCID:PMC3620356
  • Hoot, S., McGuire, A. T., Cohen, K. W., Strong, R. K., Hangartner, L., Klein, F., Diskin, R., Scheid, J. F., Sather, D. N., Burton, D. R., Stamatatos, L. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs. PLoS Pathogens  2013 9:e1003106  DOI:10.1371/journal.ppat.1003106  PMID:23300456  PMCID:PMC3536657
  • Changela, A., Wu, X., Yang, Y., Zhang, B., Zhu, J., Nardone, G. A., O'Dell, S., Pancera, M., Gorny, M. K., Phogat, S., Robinson, J. E., Stamatatos, L., et al. Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1 Journal of Virology  2011 85:2524-2535  DOI:10.1128/jvi.02335-10  PMID:21191009  PMCID:PMC3067962
  • Correia, B. E., Ban, Y. E., Friend, D. J., Ellingson, K., Xu, H., Boni, E., Bradley-Hewitt, T., Bruhn-Johannsen, J. F., Stamatatos, L., Strong, R. K., Schief, W. R. Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design Journal of Molecular Biology  2011 405:284-297  DOI:10.1016/j.jmb.2010.09.061  PMID:20969873
  • Correia, B. E., Ban, Y. E. A., Holmes, M. A., Xu, H. Y., Ellingson, K., Kraft, Z., Carrico, C., Boni, E., Sather, D. N., Zenobia, C., Burke, K. Y., Bradley-Hewitt, T., et al. Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic hiv vaccine epitope Structure  2010 18:1116-1126  DOI:10.1016/j.str.2010.06.010  PMID:20826338
  • Schief, W. R., Ban, Y. E. A., Stamatatos, L. Challenges for structure-based HIV vaccine design Current Opinion in HIV and AIDS  2009 4:431-440  DOI:10.1097/COH.0b013e32832e6184  PMID:20048708
  • Stamatatos, L., Morris, L., Burton, D. R., Mascola, J. R. Neutralizing antibodies generated during natural hiv-1 infection: Good news for an hiv-1 vaccine? Nature Medicine  2009 15:866-870  DOI:10.1038/nm.1949  PMID:19525964
  • Mo, H. M., Stamatatos, L., Ip, J. E., Barbas, C. F., Parren, Pwhi, Burton, D. R., Moore, J. P., Ho, D. D. Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody igg1b12 Journal of Virology  1997 71:6869-6874  PMID:9261412  PMCID:PMC191968