recent publications
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academic article
- Dosenovic, P., von Boehmer, L., Escolano, A., Jardine, J., Freund, N. T., Gitlin, A. D., McGuire, A. T., Kulp, D. W., Oliveira, T., Scharf, L., Pietzsch, J., Gray, M. D., et al. Immunization for HIV-1 broadly neutralizing antibodies in human Ig knockin mice Cell 2015 161:1505-1515 DOI:10.1016/j.cell.2015.06.003 PMID:26091035 PMCID:PMC4604566
- Zhou, T., Lynch, R. M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N. A., Joyce, M. G., Lingwood, D., Soto, C., Bailer, R. T., Ernandes, M. J., Kong, R., et al. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Cell 2015 161:1280-1292 DOI:10.1016/j.cell.2015.05.007 PMID:26004070 PMCID:PMC4683157
- Jardine, J., Julien, J. P., Menis, S., Ota, T., Kalyuzhniy, O., McGuire, A., Sok, D., Huang, P. S., MacPherson, S., Jones, M., Nieusma, T., Mathison, J., et al. Rational HIV immunogen design to target specific germline B cell receptors Science 2013 340:711-716 DOI:10.1126/science.1234150 PMID:23539181 PMCID:PMC3689846
- McGuire, A. T., Hoot, S., Dreyer, A. M., Lippy, A., Stuart, A., Cohen, K. W., Jardine, J., Menis, S., Scheid, J. F., West, A. P., Schief, W. R., Stamatatos, L. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies Journal of Experimental Medicine 2013 210:655-663 DOI:10.1084/jem.20122824 PMID:23530120 PMCID:PMC3620356
- Hoot, S., McGuire, A. T., Cohen, K. W., Strong, R. K., Hangartner, L., Klein, F., Diskin, R., Scheid, J. F., Sather, D. N., Burton, D. R., Stamatatos, L. Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs. PLoS Pathogens 2013 9:e1003106 DOI:10.1371/journal.ppat.1003106 PMID:23300456 PMCID:PMC3536657
- Changela, A., Wu, X., Yang, Y., Zhang, B., Zhu, J., Nardone, G. A., O'Dell, S., Pancera, M., Gorny, M. K., Phogat, S., Robinson, J. E., Stamatatos, L., et al. Crystal structure of human antibody 2909 reveals conserved features of quaternary structure-specific antibodies that potently neutralize HIV-1 Journal of Virology 2011 85:2524-2535 DOI:10.1128/jvi.02335-10 PMID:21191009 PMCID:PMC3067962
- Correia, B. E., Ban, Y. E., Friend, D. J., Ellingson, K., Xu, H., Boni, E., Bradley-Hewitt, T., Bruhn-Johannsen, J. F., Stamatatos, L., Strong, R. K., Schief, W. R. Computational protein design using flexible backbone remodeling and resurfacing: case studies in structure-based antigen design Journal of Molecular Biology 2011 405:284-297 DOI:10.1016/j.jmb.2010.09.061 PMID:20969873
- Correia, B. E., Ban, Y. E. A., Holmes, M. A., Xu, H. Y., Ellingson, K., Kraft, Z., Carrico, C., Boni, E., Sather, D. N., Zenobia, C., Burke, K. Y., Bradley-Hewitt, T., et al. Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic hiv vaccine epitope Structure 2010 18:1116-1126 DOI:10.1016/j.str.2010.06.010 PMID:20826338
- Schief, W. R., Ban, Y. E. A., Stamatatos, L. Challenges for structure-based HIV vaccine design Current Opinion in HIV and AIDS 2009 4:431-440 DOI:10.1097/COH.0b013e32832e6184 PMID:20048708
- Stamatatos, L., Morris, L., Burton, D. R., Mascola, J. R. Neutralizing antibodies generated during natural hiv-1 infection: Good news for an hiv-1 vaccine? Nature Medicine 2009 15:866-870 DOI:10.1038/nm.1949 PMID:19525964
- Mo, H. M., Stamatatos, L., Ip, J. E., Barbas, C. F., Parren, Pwhi, Burton, D. R., Moore, J. P., Ho, D. D. Human immunodeficiency virus type 1 mutants that escape neutralization by human monoclonal antibody igg1b12 Journal of Virology 1997 71:6869-6874 PMID:9261412 PMCID:PMC191968