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Small-molecule-based strategies for controlling gene expression

Academic Article
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Overview

authors

  • Denison, C.
  • Kodadek, Thomas

publication date

  • June 1998

journal

  • Chemistry & Biology  Journal

abstract

  • A central goal in chemical biology is to gain control over biological pathways using small molecules, and the mRNA-synthesizing machinery is a particular important target. New advances in our understanding of transcriptional regulation suggests strategies to manipulate these pathways using small molecules.

subject areas

  • Animals
  • Drug Design
  • Gene Expression Regulation
  • Genetic Engineering
  • Humans
  • Models, Genetic
  • Models, Molecular
  • RNA, Messenger
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Identity

International Standard Serial Number (ISSN)

  • 1074-5521

Digital Object Identifier (DOI)

  • 10.1016/s1074-5521(98)90167-3

PubMed ID

  • 9653545
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Additional Document Info

start page

  • R129

end page

  • R145

volume

  • 5

issue

  • 6

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