recent publications

• academic article

  • Moosa, M. M., Ferreon, A. C. M., Deniz, A. A. Forced folding of a disordered protein accesses an alternative folding landscape ChemPhysChem  2015 16:90-94  DOI:10.1002/cphc.201402661  PMID:25345588  PMCID:PMC4286261
  • Ferreon, A. C. M., Ferreon, J. C., Wright, P. E., Deniz, A. A. Modulation of allostery by protein intrinsic disorder Nature  2013 498:390-394  DOI:10.1038/nature12294  PMID:23783631  PMCID:PMC3718496
  • Ferreon, A. C. M., Moosa, M. M., Gambin, Y., Deniz, A. A. Counteracting chemical chaperone effects on the single-molecule alpha-synuclein structural landscape Proceedings of the National Academy of Sciences of the United States of America  2012 109:17826-17831  DOI:10.1073/pnas.1201802109  PMID:22826265  PMCID:PMC3497778
  • Ferreon, A. C. M., Deniz, A. A. Protein folding at single-molecule resolution Biochimica et Biophysica Acta-Proteins and Proteomics  2011 1814:1021-1029  DOI:10.1016/j.bbapap.2011.01.011  PMID:21303706  PMCID:PMC3114273
  • Gambin, Y., VanDelinder, V., Ferreon, A. C. M., Lemke, E. A., Groisman, A., Deniz, A. A. Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing Nature Methods  2011 8:239-241  DOI:10.1038/nmeth.1568  PMID:21297620  PMCID:PMC3071799
  • Lee, C. W., Ferreon, J. C., Ferreon, A. C. M., Arai, M., Wright, P. E. Graded enhancement of p53 binding to creb-binding protein (cbp) by multisite phosphorylation Proceedings of the National Academy of Sciences of the United States of America  2010 107:19290-19295  DOI:10.1073/pnas.1013078107  PMID:20962272  PMCID:PMC2984141
  • Ferreon, A. C. M., Moran, C. R., Ferreon, J. C., Deniz, A. A. Alteration of the α-synuclein folding landscape by a mutation related to Parkinson's disease Angewandte Chemie-International Edition  2010 49:3469-3472  DOI:10.1002/anie.201000378  PMID:20544898  PMCID:PMC2972640
  • Vandelinder, V., Ferreon, A. C. M., Gambin, Y., Deniz, A. A., Groisman, A. High-resolution temperature-concentration diagram of α-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device Analytical Chemistry  2009 81:6929-6935  DOI:10.1021/ac901008c  PMID:19555081  PMCID:PMC2846235
  • Gambin, Y., Schug, A., Lemke, E. A., Lavinder, J. J., Ferreon, A. C. M., Magliery, T. J., Onuchic, J. N., Deniz, A. A. Direct single-molecule observation of a protein living in two opposed native structures Proceedings of the National Academy of Sciences of the United States of America  2009 106:10153-10158  DOI:10.1073/pnas.0904461106  PMID:19506258  PMCID:PMC2700882
  • Ferreon, A. C. M., Gambin, Y., Lemke, E. A., Deniz, A. A. Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence Proceedings of the National Academy of Sciences of the United States of America  2009 106:5645-5650  DOI:10.1073/pnas.0809232106  PMID:19293380  PMCID:PMC2667048
  • Ferreon, A. C. M., Deniz, A. A. Alpha-synuclein multistate folding thermodynamics: Implications for protein misfolding and aggregation Biochemistry  2007 46:4499-4509  DOI:10.1021/bi602461y  PMID:17378587