recent publications

• academic article

  • Nicolaou, K. C.*, Pratt, B. A.*, Arseniyadis, S., Wartmann, M., O'Brate, A., Giannakakou, P. Molecular design and chemical synthesis of a highly potent epothilone ChemMedChem  2006 1:41-44  DOI:10.1002/cmdc.200500056  PMID:16892332 (* = equal contribution)
  • Nicolaou, K. C.*, Xu, H.*, Wartmann, M. Biomimetic total synthesis of gambogin and rate acceleration of pericyclic reactions in aqueous media Angewandte Chemie-International Edition  2005 44:756-761  DOI:10.1002/anie.200462211  PMID:15657969 (* = equal contribution)
  • Nicolaou, K. C., Sasmal, P. K., Rassias, G., Reddy, M. V., Altmann, K. H., Wartmann, M., O'Brate, A., Giannakakou, P. Design, synthesis, and biological properties of highly potent epothilone b analogues Angewandte Chemie-International Edition  2003 42:3515-3520  DOI:10.1002/anie.200351819  PMID:12900969
  • Nicolaou, K. C., Ritzen, A., Namoto, K., Buey, R. M., Diaz, J. F., Andreu, J. M., Wartmann, M., Altmann, K. H., O'Brate, A., Giannakakou, P. Chemical synthesis and biological evaluation of novel epothilone B and trans-12,13-cyclopropyl epothilone B analogues Tetrahedron  2002 58:6413-6432  DOI:10.1016/s0040-4020(02)00655-5
  • Nicolaou, K. C.*, Namoto, K.*, Ritzen, A., Ulven, T., Shoji, M., Li, J., D'Amico, G., Liotta, D., French, C. T., Wartmann, M., Altmann, K. H., Giannakakou, P. Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues Journal of the American Chemical Society  2001 123:9313-9323  DOI:10.1021/ja011338b  PMID:11562214 (* = equal contribution)
  • Sinha, S. C., Sun, J., Wartmann, M., Lerner, R. A. Synthesis of epothilone analogues by antibody-catalyzed resolution of thiazole aldol synthons on a multigram scale. Biological consequences of c-13 alkylation of epothilones ChemBioChem  2001 2:656-665  DOI:10.1002/1439-7633(20010903)2:9<656::aid-cbic656>3.0.co;2-3  PMID:11828502
  • Sinha, S. C., Sun, J., Miller, G. P., Wartmann, M., Lerner, R. A. Catalytic antibody route to the naturally occurring epothilones: Total synthesis of epothilones a-f Chemistry-a European Journal  2001 7:1691-1702  DOI:10.1002/1521-3765(20010417)7:8<1691::aid-chem16910>3.0.co;2-9  PMID:11349910
  • Nicolaou, K. C., Scarpelli, R., Bollbuck, B., Werschkun, B., Pereira, M. M. A., Wartmann, M., Altmann, K. H., Zaharevitz, D., Gussio, R., Giannakakou, P. Chemical synthesis and biological properties of pyridine epothilones Chemistry & Biology  2000 7:593-599  DOI:10.1016/s1074-5521(00)00006-5  PMID:11048950