recent publications

• academic article

  • Garaigorta, U., Ortin, J. Mutation analysis of a recombinant NS replicon shows that influenza virus NS1 protein blocks the splicing and nucleo-cytoplasmic transport of its own viral mRNA Nucleic Acids Research  2007 35:4573-4582  DOI:10.1093/nar/gkm230  PMID:17488845  PMCID:PMC1950557
  • Garaigorta, U., Falcon, A. M., Ortin, J. Genetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles Journal of Virology  2005 79:15246-15257  DOI:10.1128/jvi.79.24.15246-15257.2005  PMID:16306596  PMCID:PMC1316024
  • Sobrino, F., Palma, E. L., Beck, E., Davila, M., Delatorre, J. C., Negro, P., Villanueva, N., Ortin, J., Domingo, E. Fixation of mutations in the viral genome during an outbreak of foot-and-mouth-disease - heterogeneity and rate variations Gene  1986 50:149-159  DOI:10.1016/0378-1119(86)90320-3  PMID:3034729
  • Delatorre, J. C., Davila, M., Sobrino, F., Ortin, J., Domingo, E. Establishment of cell-lines persistently infected with foot-and-mouth-disease virus Virology  1985 145:24-35  DOI:10.1016/0042-6822(85)90198-9  PMID:2990100
  • Domingo, E., Martinezsalas, E., Sobrino, F., Delatorre, J. C., Portela, A., Ortin, J., Lopezgalindez, C., Perezbrena, P., Villanueva, N., Najera, R., Vandepol, S., Steinhauer, D., et al. The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance: a review Gene  1985 40:1-8  DOI:10.1016/0378-1119(85)90017-4  PMID:3912262
  • Delatorre, J. C., Ortin, J., Domingo, E., Delamarter, J., Allet, B., Davies, J., Bertrand, K. P., Wray, L. V., Reznikoff, W. S. Plasmid vectors based on Tn10 DNA - gene-expression regulated by tetracycline Plasmid  1984 12:103-110  DOI:10.1016/0147-619x(84)90056-8  PMID:6095349