Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants

Academic Article
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related to degree

  • Mei, Tian-Sheng, Ph.D. in Chemistry, Scripps Research , transferred from Brandeis Univeristy 2007 - 2011

publication date

  • 2009

abstract

  • Pd(II)-catalyzed intramolecular amination of arenes is developed using either a one- or two-electron oxidant. The reaction protocol tolerates a wide range of deactivating groups including acetyl, cyano, and nitro groups. This catalytic reaction allows expedient syntheses of broadly useful substituted indolines or indoles.