recent publications

• academic article

  • Gupta, S., Gach, J. S., Becerra, J. C., Phan, T. B., Pudney, J., Moldoveanu, Z., Joseph, S. B., Landucci, G., Supnet, M. J., Ping, L. H., Corti, D., Moldt, B., et al. The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells PLoS Pathogens  2013 9:e1003776  DOI:10.1371/journal.ppat.1003776  PMID:24278022  PMCID:PMC3836734
  • Joseph, S. B., Bradley, M. N., Castrillo, A., Bruhn, K. W., Mak, P. A., Pei, L. M., Hogenesch, J., O'Connell, R. M., Cheng, G. H., Saez, E., Miller, J. F., Tontonoz, P. Lxr-dependent gene expression is important for macrophage survival and the innate immune response Cell  2004 119:299-309  DOI:10.1016/j.cell.2004.09.032  PMID:15479645
  • Laffitte, B. A., Chao, L. C., Li, J., Walczak, R., Hummasti, S., Joseph, S. B., Castrillo, A., Wilpitz, D. C., Mangelsdorf, D. J., Collins, J. L., Saez, E., Tontonoz, P. Activation of liver x receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue Proceedings of the National Academy of Sciences of the United States of America  2003 100:5419-5424  DOI:10.1073/pnas.0830671100  PMID:12697904  PMCID:PMC154360
  • Mak, P. A., Laffitte, B. A., Desrumaux, C., Joseph, S. B., Curtiss, L. K., Mangelsdorf, D. J., Tontonoz, P., Edwards, P. A. Regulated expression of the apolipoprotein e/c-i/c-iv/c-ii gene cluster in murine and human macrophages - a critical role for nuclear liver x receptors alpha and beta Journal of Biological Chemistry  2002 277:31900-31908  DOI:10.1074/jbc.M202993200  PMID:12032151
  • Chawla, A., Boisvert, W. A., Lee, C. H., Laffitte, B. A., Barak, Y., Joseph, S. B., Liao, D., Nagy, L., Edwards, P. A., Curtiss, L. K., Evans, R. M., Tontonoz, P. A ppar gamma-lxr-abca1 pathway in macrophages is involved in cholesterol efflux and atherogenesis Molecular Cell  2001 7:161-171  DOI:10.1016/s1097-2765(01)00164-2  PMID:11172721