Heterocyclic sulfoxide and sulfone inhibitors of fatty acid amide hydrolase

Academic Article
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publication date

  • 2005

abstract

  • A novel series of heterocyclic sulfoxides and sulfones was prepared and examined as potential inhibitors of fatty acid amide hydrolase (FAAH), the enzyme responsible for inactivation of neuromodulating fatty acid amides including anandamide and oleamide.