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Ramcharan, J.

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    • Marsilje, T. H., Labroli, M. A., Hedrick, M. P., Jin, Q., Desharnais, J., Baker, S. J., Gooljarsingh, L. T., Ramcharan, J., Tavassoli, A., Zhang, Y., Wilson, I. A., Beardsley, G. P., et al. 10-formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway Bioorganic & Medicinal Chemistry  2002 10:2739-2749  DOI:10.1016/s0968-0896(02)00102-5  PMID:12057663
    • Greasley, S. E., Horton, P., Ramcharan, J., Beardsley, G. P., Benkovic, S. J., Wilson, I. A. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis Nature Structural Biology  2001 8:402-406  DOI:10.1038/87555  PMID:11323713
    • Boger, D. L., Kochanny, M. J., Cai, H., Wyatt, D., Kitos, P. A., Warren, M. S., Ramcharan, J., Gooljarsingh, L. T., Benkovic, S. J. Design, synthesis, and evaluation of potential GAR and AICAR transformylase inhibitors Bioorganic & Medicinal Chemistry  1998 6:643-659  DOI:10.1016/s0968-0896(98)00040-6  PMID:9681131
    • Boger, D. L.*, Haynes, N. E.*, Kitos, P. A., Warren, M. S., Ramcharan, J., Marolewski, A. E., Benkovic, S. J. 10-formyl-5,8,10-trideazafolic acid (10-formyl-TDAF): a potent inhibitor of glycinamide ribonucleotide transformylase Bioorganic & Medicinal Chemistry  1997 5:1817-1830  DOI:10.1016/s0968-0896(97)00120-x  PMID:9354237 (* = equal contribution)
    • Boger, D. L.*, Haynes, N. E.*, Warren, M. S., Ramcharan, J., Marolewski, A. E., Kitos, P. A., Benkovic, S. J. Abenzyl 10-formyl-trideazafolic acid (abenzyl 10-formyl-TDAF): an effective inhibitor of glycinamide ribonucleotide transformylase Bioorganic & Medicinal Chemistry  1997 5:1847-1852  DOI:10.1016/s0968-0896(97)00123-5  PMID:9354240 (* = equal contribution)
    • Boger, D. L.*, Haynes, N. E.*, Warren, M. S., Ramcharan, J., Kitos, P. A., Benkovic, S. J. Functionalized analogues of 5,8,10-trideazafolate: Development of an enzyme-assembled tight binding inhibitor of GAR Tfase and a potential irreversible inhibitor of AICAR Tfase Bioorganic & Medicinal Chemistry  1997 5:1839-1846  DOI:10.1016/s0968-0896(97)00122-3  PMID:9354239 (* = equal contribution)
    • Boger, D. L.*, Haynes, N. E.*, Warren, M. S., Ramcharan, J., Kitos, P. A., Benkovic, S. J. Multisubstrate analogue based on 5,8,10-trideazafolate Bioorganic & Medicinal Chemistry  1997 5:1853-1857  DOI:10.1016/s0968-0896(97)00124-7  PMID:9354241 (* = equal contribution)
    • Boger, D. L.*, Haynes, N. E.*, Warren, M. S., Gooljarsingh, L. T., Ramcharan, J., Kitos, P. A., Benkovic, S. J. Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of gar tfase or aicar tfase Bioorganic & Medicinal Chemistry  1997 5:1831-1838  DOI:10.1016/s0968-0896(97)00121-1  PMID:9354238 (* = equal contribution)

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