recent publications
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academic article
- Trewhella, J., Hendrickson, W. A., Kleywegt, G. J., Sali, A., Sato, M., Schwede, T., Svergun, D. I., Tainer, J. A., Westbrook, J., Berman, H. M. Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB Structure 2013 21:875-881 DOI:10.1016/j.str.2013.04.020 PMID:23747111
- Xie, H., Ng, D., Savinov, S. N., Dey, B., Kwong, P. D., Wyatt, R., Smith, A. B., Hendrickson, W. A. Structure-activity relationships in the binding of chemically derivatized cd4 to gp120 from human immunodeficiency virus Journal of Medicinal Chemistry 2007 50:4898-4908 DOI:10.1021/jm070564e PMID:17803292 PMCID:PMC2532594
- Huang, C. C., Stricher, F., Martin, L., Decker, J. M., Majeed, S., Barthe, P., Hendrickson, W. A., Robinson, J., Roumestand, C., Sodroski, J., Wyatt, R., Shaw, G. M., et al. Scorpion-toxin mimics of cd4 in complex with human immunodeficiency virus gp120: Crystal structures, molecular mimicry, and neutralization breadth Structure 2005 13:755-768 DOI:10.1016/j.str.2005.03.006 PMID:15893666
- Huang, C. C., Venturi, M., Majeed, S., Moore, M. J., Phogat, S., Zhang, M. Y., Dimitrov, D. S., Hendrickson, W. A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., et al. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proceedings of the National Academy of Sciences of the United States of America 2004 101:2706-2711 DOI:10.1073/pnas.0308527100 PMID:14981267 PMCID:PMC365685
- Koch, M., Pancera, M., Kwong, P. D., Kolchinsky, P., Grundner, C., Wang, L. P., Hendrickson, W. A., Sodroski, J., Wyatt, R. Structure-based, targeted deglycosylation of hiv-1 gp120 and effects on neutralization sensitivity and antibody recognition Virology 2003 313:387-400 DOI:10.1016/s0042-6822(03)00294-0 PMID:12954207
- Kwong, P. D., Doyle, M. L., Casper, D. J., Cicala, C., Leavitt, S. A., Majeed, S., Steenbeke, T. D., Venturi, M., Chaiken, I., Fung, M., Katinger, H., Parren, Pwlh, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature 2002 420:678-682 DOI:10.1038/nature01188 PMID:12478295
- Xiang, S. H., Kwong, P. D., Gupta, R., Rizzuto, C. D., Casper, D. J., Wyatt, R., Wang, L. P., Hendrickson, W. A., Doyle, M. L., Sodroski, J. Mutagenic stabilization and/or disruption of a cd4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein Journal of Virology 2002 76:9888-9899 DOI:10.1128/jvi.76.19.9888-9899.2002 PMID:12208966
- Kwong, P. D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R. W., Sodroski, J., Hendrickson, W. A. Structures of hiv-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates Structure 2000 8:1329-1339 DOI:10.1016/s0969-2126(00)00547-5 PMID:11188697
- Myszka, D. G., Sweet, R. W., Hensley, P., Brigham-Burke, M., Kwong, P. D., Hendrickson, W. A., Wyatt, R., Sodroski, J., Doyle, M. L. Energetics of the hiv gp120-cd4 binding reaction Proceedings of the National Academy of Sciences of the United States of America 2000 97:9026-9031 DOI:10.1073/pnas.97.16.9026 PMID:10922058
- Kwong, P. D., Wyatt, R., Sattentau, Q. J., Sodroski, J., Hendrickson, W. A. Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus Journal of Virology 2000 74:1961-1972 DOI:10.1128/jvi.74.4.1961-1972.2000 PMID:10644369
- Kwong, P. D., Wyatt, R., Desjardins, E., Robinson, J., Culp, J. S., Hellmig, B. D., Sweet, R. W., Sodroski, J., Hendrickson, W. A. Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (hiv-1) Journal of Biological Chemistry 1999 274:4115-4123 DOI:10.1074/jbc.274.7.4115 PMID:9933605
- Rizzuto, C. D., Wyatt, R., Hernandez-Ramos, N., Sun, Y., Kwong, P. D., Hendrickson, W. A., Sodroski, J. A conserved hiv gp120 glycoprotein structure involved in chemokine receptor binding Science 1998 280:1949-1953 DOI:10.1126/science.280.5371.1949 PMID:9632396
- Kwong, P. D., Wyatt, R., Robinson, J., Sweet, R. W., Sodroski, J., Hendrickson, W. A. Structure of an hiv gp120 envelope glycoprotein in complex with the cd4 receptor and a neutralizing human antibody Nature 1998 393:648-659 PMID:9641677
- Tainer, J. A., Getzoff, E. D., Alexander, H., Houghten, R. A., Olson, A. J., Lerner, R. A., Hendrickson, W. A. The reactivity of anti-peptide antibodies is a function of the atomic mobility of sites in a protein Nature 1984 312:127-134 DOI:10.1038/312127a0 PMID:6209578
- Alden, R. A., Bricogne, G., Freer, S. T., Hall, S. R., Hendrickson, W. A., Machin, P. A., Munn, R. J., Olson, A. J., Reeke, G. N., Sheriff, S., Stewart, J. M., Sygusch, J., et al. Cooperative programming in crystallography Computers and Chemistry 1983 7:137-148 DOI:10.1016/0097-8485(83)85005-0