Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
As of April 1st VIVO Scientific Profiles will no longer updated for faculty, and the link to VIVO will be removed from the library website. Faculty profile pages will continue to be updated via Interfolio. VIVO will continue being used behind the scenes to update graduate student profiles. Please contact helplib@scripps.edu if you have questions.
How to download citations from VIVO | Alternative profile options
placeholder image
Publications in VIVO
 
    Export Publications Table
co-author
Co-author Network
map of science
Map of Science

Hoebe, K.

share the uri
  • Publications
scroll to property group menus

Publications

recent publications

  • academic article

    • Tardif, V., Manenkova, Y., Berger, M., Hoebe, K., Zuo, J. P., Yuan, C., Kono, D. H., Theofilopoulos, A. N., Lawson, B. R. Critical role of transmethylation in TLR signaling and systemic lupus erythematosus Clinical Immunology  2013 147:133-143  DOI:10.1016/j.clim.2013.02.018  PMID:23583916  PMCID:PMC3634912
    • Arnold, C. N., Barnes, M. J., Berger, M., Blasius, A. L., Brandl, K., Croker, B., Crozat, K., Du, X., Eidenschenk, C., Georgel, P., Hoebe, K., Huang, H., et al. ENU-induced phenovariance in mice: Inferences from 587 mutations BMC Research Notes  2012 5:577  DOI:10.1186/1756-0500-5-577  PMID:23095377  PMCID:PMC3532239
    • Barnes, M. J., Aksoylar, H., Krebs, P., Bourdeau, T., Arnold, C. N., Xia, Y., Khovananth, K., Engel, I., Sovath, S., Lampe, K., Laws, E., Saunders, A., et al. Loss of t cell and b cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in gimap5-deficient mice Journal of Immunology  2010 184:3743-3754  DOI:10.4049/jimmunol.0903164  PMID:20190135  PMCID:PMC4395861
    • Jimenez-Dalmaroni, M. J., Xiao, N. M., Corper, A. L., Verdino, P., Ainge, G. D., Larsen, D. S., Painter, G. F., Rudd, P. M., Dwek, R. A., Hoebe, K., Beutler, B., Wilson, I. A. Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2 PLoS One  2009 4:e7411  DOI:10.1371/journal.pone.0007411  PMID:19847289  PMCID:PMC2760212
    • Krebs, P., Barnes, M. J., Lampe, K., Whitley, K., Bahjat, K. S., Beutler, B., Janssen, E., Hoebe, K. Nk cell-mediated killing of target cells triggers robust antigen-specific t cell-mediated and humoral responses Blood  2009 113:6593-6602  DOI:10.1182/blood-2009-01-201467  PMID:19406986  PMCID:PMC2710917
    • Barnes, M. J., Krebs, P., Harris, N., Eidenschenk, C., Gonzalez-Quintial, R., Arnold, C. N., Crozat, K., Sovath, S., Moresco, E. M., Theofilopoulos, A. N., Beutler, B., Hoebe, K. Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery PLoS Biology  2009 7:e1000051  DOI:10.1371/journal.pbio.1000051  PMID:19260764  PMCID:PMC2650725
    • Chaix, J., Tessmer, M. S., Hoebe, K., Fuseri, N., Ryffel, B., Dalod, M., Alexopoulou, L., Beutler, B., Brossay, L., Vivier, E., Walzer, T. Cutting edge: Priming of NK cells by IL-18 Journal of Immunology  2008 181:1627-1631  PMID:18641298
    • Hoebe, K., Beutler, B. Forward genetic analysis of TLR-signaling pathways: an evaluation Advanced Drug Delivery Reviews  2008 60:824-829  DOI:10.1016/j.addr.2008.02.002  PMID:18331766
    • Huang, Y. H., Hoebe, K., Sauer, K. New therapeutic targets in immune disorders: Itpkb, orai1 and unc93b Expert Opinion on Therapeutic Targets  2008 12:391-413  DOI:10.1517/14728222.12.4.391  PMID:18348677
    • Georgel, P., Du, X., Hoebe, K., Beutler, B. ENU mutagenesis in mice Methods in Molecular Biology  2008 415:1-16  DOI:10.1007/978-1-59745-570-1_1  PMID:18370145
    • Georgel, P., Jiang, Z. F., Kunz, S., Janssen, E., Mols, J., Hoebe, K., Bahram, S., Oldstone, M. B. A., Beutler, B. Vesicular stomatitis virus glycoprotein g activates a specific antiviral toll-like receptor 4-dependent pathway Virology  2007 362:304-313  DOI:10.1016/j.virol.2006.12.032  PMID:17292937
    • Baccala, R., Hoebe, K., Kono, D. H., Beutler, B., Theofilopoulos, A. N. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity Nature Medicine  2007 13:543-551  DOI:10.1038/nm1590  PMID:17479100
    • Brinkmann, M. M., Spooner, E., Hoebe, K., Beutler, B., Ploegh, H. L., Kim, Y. M. The interaction between the er membrane protein unc93b and tlr3, 7, and 9 is crucial for tlr signaling Journal of Cell Biology  2007 177:265-275  DOI:10.1083/jcb.200612056  PMID:17452530  PMCID:PMC2064135
    • Crozat, K., Hoebe, K., Ugolini, S., Hong, N. A., Janssen, E., Rutschmann, S., Mudd, S., Sovath, S., Vivier, E., Beutler, B. Jinx, an mcmv susceptibility phenotype caused by disruption of unc13d: A mouse model of type 3 familial hemophagocytic lymphohistiocytosis Journal of Experimental Medicine  2007 204:853-863  DOI:10.1084/jem.20062447  PMID:17420270  PMCID:PMC2118559
    • Gavin, A. L., Hoebe, K., Duong, B., Ota, T., Martin, C., Beutler, B., Nemazee, D. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling Science  2006 314:1936-1938  DOI:10.1126/science.1135299  PMID:17185603  PMCID:PMC1868398
    • Togbe, D., Aurore, G., Noulin, N., Quesniaux, V. F. J., Schnyder-Candrian, S., Schnyder, B., Vasseur, V., Akira, S., Hoebe, K., Beutler, B., Ryffel, B., Couillin, I. Nonredundant roles of tirap and myd88 in airway response to endotoxin, independent of trif, il-1 and il-18 pathways Laboratory Investigation  2006 86:1126-1135  DOI:10.1038/labinvest.3700473  PMID:16983331
    • Casrouge, A., Zhang, S. Y., Eidenschenk, C., Jouanguy, E., Puel, A., Yang, K., Alcais, A., Picard, C., Mahfoufi, N., Nicolas, N., Lorenzo, L., Plancoulaine, S., et al. Herpes simplex virus encephalitis in human unc-93b deficiency Science  2006 314:308-312  DOI:10.1126/science.1128346  PMID:16973841
    • Kinjo, Y., Tupin, E., Wu, D., Fujio, M., Garcia-Navarro, R., Benhnia, Mrei, Zajonc, D. M., Ben-Menachem, G., Ainge, G. D., Painter, G. F., Khurana, A., Hoebe, K., et al. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria Nature Immunology  2006 7:978-986  DOI:10.1038/ni1380  PMID:16921381
    • Rutschmann, S., Hoebe, K., Zalevsky, J., Du, X., Mann, N., Dahiyat, B. I., Steed, P., Beutler, B. PanR1, a dominant negative missense allele of the gene encoding TNF-alpha (Tnf), does not impair lymphoid development Journal of Immunology  2006 176:7525-7532  PMID:16751399
    • Janssen, E., Tabeta, K., Barnes, M. J., Rutschmann, S., McBride, S., Bahjat, K. S., Schoenberger, S. P., Theofilopoulos, A. N., Beutler, B., Hoebe, K. Efficient t cell activation via a toll-interleukin 1 receptor-independent pathway Immunity  2006 24:787-799  DOI:10.1016/j.immuni.2006.03.024  PMID:16782034
    • Nemazee, D., Gavin, A., Hoebe, K., Beutler, B. Immunology: Toll-like receptors and antibody responses Nature  2006 441:E4  DOI:10.1038/nature04875  PMID:16710369  PMCID:PMC3787862
    • Crozat, K., Georgel, P., Rutschmann, S., Mann, N., Du, X., Hoebe, K., Beutler, B. Analysis of the MCMV resistome by ENU mutagenesis Mammalian Genome  2006 17:398-406  DOI:10.1007/s00335-005-0164-2  PMID:16688530
    • Hoebe, K., Beutler, B. Traf3: A new component of the tlr-signaling apparatus Trends in Molecular Medicine  2006 12:187-189  DOI:10.1016/j.molmed.2006.03.008  PMID:16621716
    • Tabeta, K., Hoebe, K., Janssen, E. M., Du, X., Georgel, P., Crozat, K., Mudd, S., Mann, N., Sovath, S., Goode, J., Shamel, L., Herskovits, A. A., et al. The unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via toll-like receptors 3, 7 and 9 Nature Immunology  2006 7:156-164  DOI:10.1038/ni1297  PMID:16415873
    • Beutler, B., Jiang, Z. F., Georgel, P., Crozat, K., Croker, B., Rutschmann, S., Du, X., Hoebe, K. Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large Annual Review of Immunology  2006 24:353-389  DOI:10.1146/annurev.immunol.24.021605.090552  PMID:16551253
    • Hoebe, K., Jiang, Z., Georgel, P., Tabeta, K., Janssen, E., Du, X., Beutler, B. TLR signaling pathways: Opportunities for activation and blockade in pursuit of therapy Current Pharmaceutical Design  2006 12:4123-4134  DOI:10.2174/138161206778743466  PMID:17100615
    • Wieland, C. W., Florquin, S., Maris, N. A., Hoebe, K., Beutler, B., Takeda, K., Akira, S., van der Poll, T. The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable Haemophilus influenzae from the mouse lung Journal of Immunology  2005 175:6042-6049  PMID:16237099
    • Georgel, P., Crozat, K., Lauth, X., Makrantonaki, E., Seltmann, H., Sovath, S., Hoebe, K., Du, X., Rutschmann, S., Jiang, Z. F., Bigby, T., Nizet, V., et al. A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria Infection and Immunity  2005 73:4512-4521  DOI:10.1128/iai.73.8.4512-4521.2005  PMID:16040962
    • Kim, K. I., Malakhova, O. A., Hoebe, K., Yan, M., Beutler, B., Zhang, D. E. Enhanced antibacterial potential in UBP43-deficient mice against Salmonella typhimurium infection by up-regulation type IIFN signaling Journal of Immunology  2005 175:847-854  PMID:16002682
    • Zhou, Z. P., Hoebe, K., Du, X., Jiang, Z. F., Shamel, L., Beutler, B. Antagonism between MyD88- and TRIF-dependent signals in B7RP-1 up-regulation European Journal of Immunology  2005 35:1918-1927  DOI:10.1002/eji.200525971  PMID:15884053
    • Hoebe, K., Beutler, B. Unraveling innate immunity using large scale n-ethyl-n-nitrosourea mutagenesis Tissue Antigens  2005 65:395-401  DOI:10.1111/j.1399-0039.2005.00369.x  PMID:15853894
    • Mattner, J., DeBord, K. L., Ismail, N., Goff, R. D., Cantu, C., Zhou, D. P., Saint-Mezard, P., Wang, V., Gao, Y., Yin, N., Hoebe, K., Schneewind, O., et al. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections Nature  2005 434:525-529  DOI:10.1038/nature03408  PMID:15791258
    • Hoebe, K., Georgel, P., Rutschmann, S., Du, X., Mudd, S., Crozat, K., Sovath, S., Shamel, L., Hartung, T., Zahringer, U., Beutler, B. Cd36 is a sensor of diacylglycerides Nature  2005 433:523-527  DOI:10.1038/nature03253  PMID:15690042
    • Beutler, B., Hoebe, K., Georgel, P., Tabeta, K., Du, X. Genetic analysis of innate immunity: Identification and function of the tir adapter proteins Advances in Experimental Medicine and Biology  2005 560:29-39  DOI:10.1007/0-387-24180-9_4  PMID:15934170
    • Beutler, B., Hoebe, K., Georgel, P., Tabeta, K., Du, X. Genetic analysis of innate immunity: Tir adapter proteins in innate and adaptive immune responses Microbes and Infection  2004 6:1374-1381  DOI:10.1016/j.micinf.2004.08.017  PMID:15596123
    • Hoebe, K., Janssen, E., Beutler, B. The interface between innate and adaptive immunity Nature Immunology  2004 5:971-974  DOI:10.1038/ni1004-971  PMID:15454919
    • Anfossi, N., Robbins, S. H., Ugolini, S., Georgel, P., Hoebe, K., Bouneaud, C., Ronet, C., Kaser, A., DiCioccio, C. B., Tomasello, E., Blumberg, R. S., Beutler, B., et al. Expansion and function of CD8(+) T cells, expressing Ly49 inhibitory receptors specific for MHC class I molecules Journal of Immunology  2004 173:3773-3782  PMID:15356124
    • Beutler, B., Hoebe, K., Shamel, L. Forward genetic dissection of afferent immunity: The role of tir adapter proteins in innate and adaptive immune responses Comptes Rendus Biologies  2004 327:571-580  DOI:10.1016/j.crvi.2004.03.008  PMID:15330256
    • Tabeta, K., Georgel, P., Janssen, E., Du, X., Hoebe, K., Crozat, K., Mudd, S., Shamel, L., Sovath, S., Goode, J., Alexopoulou, L., Flavell, R. A., et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection Proceedings of the National Academy of Sciences of the United States of America  2004 101:3516-3521  DOI:10.1073/pnas.0400525101  PMID:14993594  PMCID:PMC373494
    • Weighardt, H., Jusek, G., Mages, J., Lang, R., Hoebe, K., Beutler, B., Holzmann, B. Identification of a tlr4- and trif-dependent activation program of dendritic cells European Journal of Immunology  2004 34:558-564  DOI:10.1002/eji.200324714  PMID:14768061
    • Hoebe, K., Beutler, B. Lps, dsrna and the interferon bridge to adaptive immune responses: Trif, tram, and other tir adaptor proteins Journal of Endotoxin Research  2004 10:130-136  DOI:10.1179/096805104225004031  PMID:15120005
    • Du, X., Tabeta, K., Hoebe, K., Liu, H. Q., Mann, N., Mudd, S., Crozat, K., Sovath, S., Gong, X. H., Beutler, B. Velvet, a dominant egfr mutation that causes wavy hair and defective eyelid development in mice Genetics  2004 166:331-340  DOI:10.1534/genetics.166.1.331  PMID:15020428
    • Hoebe, K., Janssen, E. M., Kim, S. O., Alexopoulou, L., Flavell, R. A., Han, J. H., Beutler, B. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded rna occurs by trif-dependent and trif-independent pathways Nature Immunology  2003 4:1223-1229  DOI:10.1038/ni1010  PMID:14625548
    • Beutler, B., Hoebe, K., Du, X., Ulevitch, R. J. How we detect microbes and respond to them: The toll-like receptors and their transducers Journal of Leukocyte Biology  2003 74:479-485  DOI:10.1189/jlb.0203082  PMID:12960260
    • Beutler, B., Hoebe, K., Du, X., Janssen, E., Georgel, P., Tabeta, K. Lps2 and signal transduction in sepsis: At the intersection of host responses to bacteria and viruses Scandinavian Journal of Infectious Diseases  2003 35:563-567  DOI:10.1080/00365540310016295  PMID:14620135
    • Hoebe, K., Du, X., Georgel, P., Janssen, E., Tabeta, K., Kim, S. O., Goode, J., Lin, P., Mann, N., Mudd, S., Crozat, K., Sovath, S., et al. Identification of lps2 as a key transducer of myd88-independent tir signalling Nature  2003 424:743-748  DOI:10.1038/nature01889  PMID:12872135
    • Beutler, B., Du, X., Hoebe, K. From phenomenon to phenotype and from phenotype to gene: Forward genetics and the problem of sepsis Journal of Infectious Diseases  2003 187:S321-S326  DOI:10.1086/374757  PMID:12792846
    • Kim, S. O., Jing, Q., Hoebe, K., Beutler, B., Duesbery, N. S., Han, J. H. Sensitizing anthrax lethal toxin-resistant macrophages to lethal toxin-induced killing by tumor necrosis factor-alpha Journal of Biological Chemistry  2003 278:7413-7421  DOI:10.1074/jbc.M209279200  PMID:12488448
    • Hoebe, K., Du, X., Goode, J., Mann, N., Beutler, B. Lps2: A new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening Journal of Endotoxin Research  2003 9:250-255  DOI:10.1179/096805103225001459  PMID:12935356

©2022 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support