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Nievergelt, C. M.

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    • Rana, B. K., Darst, B. F., Bloss, C., Shih, P. A. B., Depp, C., Nievergelt, C. M., Allison, M., Parsons, J. K., Schork, N., Jeste, D. V. Candidate SNP associations of optimism and resilience in older adults: exploratory study of 935 community-dwelling adults American Journal of Geriatric Psychiatry  2014 22:997-1006  DOI:10.1016/j.jagp.2014.03.009  PMID:24791650  PMCID:PMC4163500
    • Nievergelt, C. M., Wineinger, N. E., Libiger, O., Pham, P., Zhang, G., Baker, D. G., Marine Resiliency Study Investigators, Schork, N. J. Chip-based direct genotyping of coding variants in genome wide association studies: utility, issues and prospects Gene  2014 540:104-109  DOI:10.1016/j.gene.2014.01.069  PMID:24521671  PMCID:PMC3980715
    • Zhang, K., Huentelman, M. J., Rao, F., Sun, E. I., Corneveaux, J. J., Schork, A. J., Wei, Z., Waalen, J., Miramontes-Gonzalez, J. P., Hightower, C. M., Maihofer, A. X., Mahata, M., et al. Genetic implication of a novel thiamine transporter in human hypertension Journal of the American College of Cardiology  2014 63:1542-1555  DOI:10.1016/j.jacc.2014.01.007  PMID:24509276  PMCID:PMC3992204
    • Yurgil, K. A., Barkauskas, D. A., Vasterling, J. J., Nievergelt, C. M., Larson, G. E., Schork, N. J., Litz, B. T., Nash, W. P., Baker, D. G., Marine Resiliency Study Team Association between traumatic brain injury and risk of posttraumatic stress disorder in active-duty Marines JAMA Psychiatry  2014 71:149-157  DOI:10.1001/jamapsychiatry.2013.3080  PMID:24337530
    • Zhang, K., Deacon, D. C., Rao, F., Schork, A. J., Fung, M. M., Waalen, J., Schork, N. J., Nievergelt, C. M., Chi, N. C., O'Connor, D. T. Human heart rate: heritability of resting and stress values in twin pairs, and influence of genetic variation in the adrenergic pathway at a microribonucleic acid microRNA motif in the 3'-UTR of cytochrome b561 Journal of the American College of Cardiology  2014 63:358-368  DOI:10.1016/j.jacc.2013.09.025  PMID:24140660  PMCID:PMC3946708
    • Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Nature Genetics  2013 45:984-994  DOI:10.1038/ng.2711  PMID:23933821  PMCID:PMC3800159
    • Gamazon, E. R., Badner, J. A., Cheng, L., Zhang, C., Zhang, D., Cox, N. J., Gershon, E. S., Kelsoe, J. R., Greenwood, T. A., Nievergelt, C. M., Chen, C., McKinney, R., et al. Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants Molecular Psychiatry  2013 18:340-346  DOI:10.1038/mp.2011.174  PMID:22212596  PMCID:PMC3601550
    • Zhang, K. X., Rao, F. W., Miramontes-Gonzalez, J. P., Hightower, C. M., Vaught, B., Chen, Y. H., Greenwood, T. A., Schork, A. J., Wang, L., Mahata, M., Stridsberg, M., Khandrika, S., et al. Neuropeptide y (npy) genetic variation in the human promoter alters glucocorticoid signaling, yielding increased npy secretion and stress responses Journal of the American College of Cardiology  2012 60:1678-1689  DOI:10.1016/j.jacc.2012.06.042  PMID:23021333  PMCID:PMC3687554
    • Mbewe-Campbell, N., Wei, Z. Y., Zhang, K. X., Friese, R. S., Mahata, M., Schork, A. J., Rao, F. W., Chiron, S., Biswas, N., Kim, H. S., Mahata, S. K., Waalen, J., et al. Genes and environment: Novel, functional polymorphism in the human cathepsin l (ctsl1) promoter disrupts a xenobiotic response element (xre) to alter transcription and blood pressure Journal of Hypertension  2012 30:1961-1969  DOI:10.1097/HJH.0b013e328356b86a  PMID:22871890  PMCID:PMC3478326
    • Friese, R. S., Ye, C., Nievergelt, C. M., Schork, A. J., Mahapatra, N. R., Rao, F., Napolitan, P. S., Waalen, J., Ehret, G. B., Munroe, P. B., Schmid-Schonbein, G. W., Eskin, E., et al. Integrated computational and experimental analysis of the neuroendocrine transcriptome in genetic hypertension identifies novel control points for the cardiometabolic syndrome Circulation-Cardiovascular Genetics  2012 5:430-440  DOI:10.1161/circgenetics.111.962415  PMID:22670052  PMCID:PMC3467001
    • Baker, D. G., Nash, W. P., Litz, B. T., Geyer, M. A., Risbrough, V. B., Nievergelt, C. M., O'Connor, D. T., Larson, G. E., Schork, N. J., Vasterling, J. J., Hammer, P. S., Webb-Murphy, J. A., et al. Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency Study Preventing Chronic Disease  2012 9:110134  DOI:10.5888/pcd9.110134  PMID:22575082  PMCID:PMC3431952
    • Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., Blackwood, D., Corvin, A., Flickinger, M., et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near odz4 Nature Genetics  2011 43:977-983  DOI:10.1038/ng.943  PMID:21926972  PMCID:PMC3637176
    • Koller, D. L., Panganiban, C., Szelinger, S., Badner, J. A., Barrett, T. B., Berrettini, W. H., Bloss, C. S., Byerley, W., Coryell, W., Edenberg, H. J., Foroud, T., Gershon, E. S., et al. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes PLoS Genetics  2011 7:e1002134  DOI:10.1371/journal.pgen.1002134  PMID:21738484  PMCID:PMC3128104
    • Laurent, L. C., Ulitsky, I., Slavin, I., Tran, H., Schork, A., Morey, R., Lynch, C., Harness, J. V., Lee, S., Barrero, M. J., Ku, S., Martynova, M., et al. Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture Cell Stem Cell  2011 8:106-118  DOI:10.1016/j.stem.2010.12.003  PMID:21211785  PMCID:PMC3043464
    • Chen, Y. Q., Salem, R. M., Rao, F. W., Fung, M. M., Bhatnagar, V., Pandey, B., Mahata, M., Waalen, J., Nievergelt, C. M., Lipkowitz, M. S., Hamilton, B. A., Mahata, S. K., et al. Common charge-shift mutation glu65lys in k(+) channel beta(1)-subunit kcnmb1: Pleiotropic consequences for glomerular filtration rate and progressive renal disease American Journal of Nephrology  2010 32:414-424  DOI:10.1159/000320131  PMID:20861615  PMCID:PMC2975731
    • Chen, Y. Q., Lipkowitz, M. S., Salem, R. M., Fung, M. M., Bhatnagar, V., Mahata, M., Nievergelt, C. M., Rao, F. W., Mahata, S. K., Schork, N. J., Hicks, P. J., Bowden, D. W., et al. Progression of chronic kidney disease: Adrenergic genetic influence on glomerular filtration rate decline in hypertensive nephrosclerosis American Journal of Nephrology  2010 32:23-30  DOI:10.1159/000313927  PMID:20484896  PMCID:PMC2914391
    • Laurent, L. C., Nievergelt, C. M., Lynch, C., Fakunle, E., Harness, J. V., Schmidt, U., Galat, V., Laslett, A. L., Otonkoski, T., Keirstead, H. S., Schork, A., Park, H. S., et al. Restricted ethnic diversity in human embryonic stem cell lines Nature Methods  2010 7:6-7  DOI:10.1038/nmeth0110-06  PMID:20038950
    • Fung, M. M., Chen, Y. Q., Lipkowitz, M. S., Salem, R. M., Bhatnagar, V., Mahata, M., Nievergelt, C. M., Rao, F. W., Mahata, S. K., Schork, N. J., Brophy, V. H., O'Connor, D. T., et al. Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis Nephrology Dialysis Transplantation  2009 24:3677-3686  DOI:10.1093/ndt/gfp471  PMID:19745105  PMCID:PMC2790952
    • Fung, M. M., Rana, B. K., Tang, C. M., Shiina, T., Nievergelt, C. M., Rao, F. W., Salem, R. M., Waalen, J., Ziegler, M. G., Insel, P. A., O'Connor, D. T. Dopamine d1 receptor (drd1) genetic polymorphism: Pleiotropic effects on heritable renal traits Kidney International  2009 76:1070-1080  DOI:10.1038/ki.2009.306  PMID:19675531  PMCID:PMC2803094
    • Libiger, O., Nievergelt, C. M., Schork, N. J. Comparison of genetic distance measures using human SNP genotype data Human Biology  2009 81:389-406  PMID:20067366
    • Bhatnagar, V., To'Connor, D., Brophy, V. H., Schork, N. J., Richard, E., Salem, R. M., Nievergelt, C. M., Bakris, G. L., Middleton, J. P., Norris, K. C., Wright, J., Hiremath, L., et al. G-protein-coupled receintor kinase 4 polymorphisms and blood pressure response to metoprolol among african americans: Sex-specificity and interactions American Journal of Hypertension  2009 22:332-338  DOI:10.1038/ajh.2008.341  PMID:19119263  PMCID:PMC2715837
    • Evans, L. M., Akiskal, H. S., Greenwood, T. A., Nievergelt, C. M., Keck, P. E., McElroy, S. L., Sadovnick, A. D., Remick, R. A., Schork, N. J., Kelsoe, J. R. Suggestive linkage of a chromosomal locus on 18p11 to cyclothymic temperament in bipolar disorder families American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2008 147B:326-332  DOI:10.1002/ajmg.b.30601  PMID:18081158
    • Barretta, T. B., Emberton, J. E., Nievergelt, C. M., Liang, S. G., Hauger, R. L., Eskin, E., Schork, N. J., Kelsoe, J. R. Further evidence for association of grk3 to bipolar disorder suggests a second disease mutation Psychiatric Genetics  2007 17:315-322  PMID:18075471
    • Bhatnagar, V., O'Connor, D. T., Schork, N. J., Salem, R. M., Nievergelt, C. M., Rana, B. K., Smith, D. W., Bakris, G. L., Middleton, J. P., Norris, K. C., Wright, J. T., Cheek, D., et al. Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the aask trial Journal of Hypertension  2007 25:2082-2092  DOI:10.1097/HJH.0b013e3282b9720e  PMID:17885551  PMCID:PMC2792638
    • Nievergelt, C. M., Libiger, O., Schork, N. J. Generalized analysis of molecular variance PLoS Genetics  2007 3:e51  DOI:10.1371/journal.pgen.0030051  PMID:17411342  PMCID:PMC1847693
    • Mathews, C. A., Nievergelt, C. M., Azzam, A., Garrido, H., Chavira, D. A., Wessel, J., Bagnarello, M., Reus, V. I., Schork, N. J. Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoarding American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2007 144B:174-182  DOI:10.1002/ajmg.b.30370  PMID:17290446
    • Nievergelt, C. M., Kripke, D. F., Barrett, T. B., Burg, E., Remick, R. A., Sadovnick, A. D., McElroy, S. L., Keck, P. E., Schork, N. J., Kelsoe, J. R. Suggestive evidence for association of the circadian genes period3 and arntl with bipolar disorder American Journal of Medical Genetics Part B-Neuropsychiatric Genetics  2006 141B:234-241  DOI:10.1002/ajmg.b.30252  PMID:16528748  PMCID:PMC2651679
    • Mustanski, B. S., DuPree, M. G., Nievergelt, C. M., Bocklandt, S., Schork, N. J., Hamer, D. H. A genomewide scan of male sexual orientation Human Genetics  2005 116:272-278  DOI:10.1007/s00439-004-1241-4  PMID:15645181
    • Reiner, A. P., Ziv, E., Lind, D. L., Nievergelt, C. M., Schork, N. J., Cummings, S. R., Phong, A., Burchard, E. G., Harris, T. B., Psaty, B. M., Kwok, P. Y. Population structure, admixture, and aging-related phenotypes in african american adults: The cardiovascular health study American Journal of Human Genetics  2005 76:463-477  DOI:10.1086/428654  PMID:15660291  PMCID:PMC1196398
    • Soares, M. L., Coelho, T., Sousa, A., Batalov, S., Conceicao, I., Sales-Luis, M. L., Ritchie, M. D., Williams, S. M., Nievergelt, C. M., Schork, N. J., Saraiva, M. J., Buxbaum, J. N. Susceptibility and modifier genes in portuguese transthyretin V30M amyloid polyneuropathy: Complexity in a single-gene disease Human Molecular Genetics  2005 14:543-553  DOI:10.1093/hmg/ddi051  PMID:15649951
    • Nievergelt, C. M., Schork, N. J. Admixture mapping as a gene discovery approach for complex human traits and diseases Current Hypertension Reports  2005 7:31-37  DOI:10.1007/s11906-005-0052-x  PMID:15683584
    • Nievergelt, C. M., Smith, D. W., Kohlenberg, J. B., Schork, N. J. Large-scale integration of human genetic and physical maps Genome Research  2004 14:1199-1205  DOI:10.1101/gr.1475304  PMID:15140834  PMCID:PMC419799

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