recent publications
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academic article
- Schoch, G. A., Yano, J. K., Sansen, S., Dansette, P. M., Stout, C. D., Johnson, E. F. Determinants of cytochrome P4502C8 substrate binding - structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid Journal of Biological Chemistry 2008 283:17227-17237 DOI:10.1074/jbc.M802180200 PMID:18413310 PMCID:PMC2427337
- Sansen, S., Yano, J. K., Reynald, R. L., Schoch, G. A., Griffin, K. J., Stout, C. D., Johnson, E. F. Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2 Journal of Biological Chemistry 2007 282:14348-14355 DOI:10.1074/jbc.M611692200 PMID:17311915
- Yano, J. K., Denton, T. T., Cerny, M. A., Zhang, X. D., Johnson, E. F., Cashman, J. R. Synthetic inhibitors of cytochrome p-450 2a6: Inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization Journal of Medicinal Chemistry 2006 49:6987-7001 DOI:10.1021/jm060519r PMID:17125252
- Yano, J. K., Hsu, M. H., Griffin, K. J., Stout, C. D., Johnson, E. F. Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen Nature Structural & Molecular Biology 2005 12:822-823 DOI:10.1038/nsmb971 PMID:16086027
- Yano, J. K., Wester, M. R., Schoch, G. A., Griffin, K. J., Stout, C. D., Johnson, E. F. The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05 Å resolution Journal of Biological Chemistry 2004 279:38091-38094 DOI:10.1074/jbc.C400293200 PMID:15258162
- Schoch, G. A., Yano, J. K., Wester, M. R., Griffin, K. J., Stout, C. D., Johnson, E. F. Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site Journal of Biological Chemistry 2004 279:9497-9503 DOI:10.1074/jbc.M312516200 PMID:14676196
- Wester, M. R., Yano, J. K., Schoch, G. A., Yang, C., Griffin, K. J., Stout, C. D., Johnson, E. F. The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0 Å resolution Journal of Biological Chemistry 2004 279:35630-35637 DOI:10.1074/jbc.M405427200 PMID:15181000