recent publications
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academic article
- Lee, J. W., Hirota, T., Kumar, A., Kim, N. J., Irle, S., Kay, S. A. Development of small-molecule cryptochrome stabilizer derivatives as modulators of the circadian clock ChemMedChem 2015 10:1489-1497 DOI:10.1002/cmdc.201500260 PMID:26174033 PMCID:PMC4576822
- Oshima, T., Yamanaka, I., Kumar, A., Yamaguchi, J., Nishiwaki-Ohkawa, T., Muto, K., Kawamura, R., Hirota, T., Yagita, K., Irle, S., Kay, S. A., Yoshimura, T., et al. C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock Angewandte Chemie-International Edition 2015 54:7193-7197 DOI:10.1002/anie.201502942 PMID:25960183
- Kumar, A., Punta, M., Axelrod, H. L., Das, D., Farr, C. L., Grant, J. C., Chiu, H. J., Miller, M. D., Coggill, P. C., Klock, H. E., Elsliger, M. A., Deacon, A. M., et al. Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake Protein Science 2014 23:1380-1391 DOI:10.1002/pro.2522 PMID:25044324 PMCID:PMC4287006
- Kumar, A., Mocklinghoff, S., Yumoto, F., Jaroszewski, L., Farr, C. L., Grzechnik, A., Nguyen, P., Weichenberger, C. X., Chiu, H. J., Klock, H. E., Elsliger, M. A., Deacon, A. M., et al. Structure of a novel winged-helix like domain from human NFRKB protein PLoS One 2012 7:e43761 DOI:10.1371/journal.pone.0043761 PMID:22984442 PMCID:PMC3439487
- Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., Ahn, H. J., Ait-Mohamed, O., et al. Guidelines for the use and interpretation of assays for monitoring autophagy Autophagy 2012 8:445-544 DOI:10.4161/auto.19496 PMID:22966490 PMCID:PMC3404883
- Parkesh, R., Childs-Disney, J. L., Nakamori, M., Kumar, A., Wang, E., Wang, T., Hoskins, J., Tran, T., Housman, D., Thornton, C. A., Disney, M. D. Design of a bioactive small molecule that targets the myotonic dystrophy type 1 RNA via an RNA motif-ligand database and chemical similarity searching Journal of the American Chemical Society 2012 134:4731-4742 DOI:10.1021/ja210088v PMID:22300544 PMCID:PMC3306011
- Kumar, A., Parkesh, R., Sznajder, L. J., Childs-Disney, J. L., Sobczak, K., Disney, M. D. Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts ACS Chemical Biology 2012 7:496-505 DOI:10.1021/cb200413a PMID:22252896 PMCID:PMC3306454
- Kumar, A., Park, H., Fang, P. F., Parkesh, R., Guo, M., Nettles, K. W., Disney, M. D. Myotonic dystrophy type 1 RNA crystal structures reveal heterogeneous 1 x 1 nucleotide UU internal loop conformations Biochemistry 2011 50:9928-9935 DOI:10.1021/bi2013068 PMID:21988728 PMCID:PMC3218087
- Kumar, A., Fang, P. F., Park, H., Guo, M., Nettles, K. W., Disney, M. D. A crystal structure of a model of the repeating r(CGG) transcript found in fragile X syndrome ChemBioChem 2011 12:2140-2142 DOI:10.1002/cbic.201100337 PMID:21766409 PMCID:PMC3379549
- Das, D., Finn, R. D., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X. H., Carlton, D., Chen, C. N., Chiu, H. J., Chiu, M., Clayton, T., et al. The crystal structure of a bacterial sufu-like protein defines a novel group of bacterial proteins that are similar to the n-terminal domain of human sufu Protein Science 2010 19:2131-2140 DOI:10.1002/pro.497 PMID:20836087 PMCID:PMC3005784
- Xu, Q. P., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X. H., Carlton, D., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., Das, D., et al. A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from bacteroides thetaiotaomicron at 2.2 A resolution Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1281-1286 DOI:10.1107/s1744309110006548 PMID:20944223 PMCID:PMC2954217
- Axelrod, H. L., Kozbial, P., McMullan, D., Krishna, S. S., Miller, M. D., Abdubek, P., Acosta, C., Astakhova, T., Carlton, D., Caruthers, J., Chiu, H. J., Clayton, T., et al. Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas Campestris pv. Campestris Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1347-1353 DOI:10.1107/s1744309109021988 PMID:20944231 PMCID:PMC2954225
- Kumar, A., Chiu, H. J., Axelrod, H. L., Morse, A., Elsliger, M. A., Wilson, I. A., Deacon, A. Ligands in psi structures Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1309-1316 DOI:10.1107/s1744309110008092 PMID:20944227 PMCID:PMC2954221
- Kumar, A., Lomize, A., Jin, K. K., Carlton, D., Miller, M. D., Jaroszewski, L., Abdubek, P., Astakhova, T., Axelrod, H. L., Chiu, H. J., Clayton, T., Das, D., et al. Open and closed conformations of two SpoiiAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1245-1253 DOI:10.1107/s1744309109042481 PMID:20944218 PMCID:PMC2954212
- Bakolitsa, C., Xu, Q. P., Rife, C. L., Abdubek, P., Astakhova, T., Axelrod, H. L., Carlton, D., Chen, C., Chiu, H. J., Clayton, T., Das, D., Deller, M. C., et al. Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1274-1280 DOI:10.1107/s1744309110032999 PMID:20944222 PMCID:PMC2954216
- Yeh, A. P., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X. H., Carlton, D., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., Das, D., et al. Structure of Bacteroides thetaiotaomicron BT2081 at 2.05 A resolution: The first structural representative of a new protein family that may play a role in carbohydrate metabolism Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1287-1296 DOI:10.1107/s1744309110028228 PMID:20944224 PMCID:PMC2954218
- Bakolitsa, C., Kumar, A., Carlton, D., Miller, M. D., Krishna, S. S., Abdubek, P., Astakhova, T., Axelrod, H. L., Chiu, H. J., Clayton, T., Deller, M. C., Duan, L. A., et al. Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1205-1210 DOI:10.1107/s1744309109023689 PMID:20944212 PMCID:PMC2954206
- Xu, Q. P., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X. H., Carlton, D., Chen, C., Chiu, H. J., Clayton, T., Das, D., Deller, M. C., et al. Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1297-1305 DOI:10.1107/s1744309110023055 PMID:20944225 PMCID:PMC2954219
- Han, G. W., Elsliger, M. A., Yeates, T. O., Xu, Q. P., Murzin, A. G., Krishna, S. S., Jaroszewski, L., Abdubek, P., Astakhova, T., Axelrod, H. L., Carlton, D., Chen, C., et al. Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15 Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1237-1244 DOI:10.1107/s1744309110025534 PMID:20944217 PMCID:PMC2954211
- Han, G. W., Yang, X. L., McMullan, D., Chong, Y. E., Krishna, S. S., Rife, C. L., Weekes, D., Brittain, S. M., Abdubek, P., Ambing, E., Astakhova, T., Axelrod, H. L., et al. Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1326-1334 DOI:10.1107/s1744309110037619 PMID:20944229 PMCID:PMC2954223
- Miller, M. D., Aravind, L., Bakolitsa, C., Rife, C. L., Carlton, D., Abdubek, P., Astakhova, T., Axelrod, H. L., Chiu, H. J., Clayton, T., Deller, M. C., Duan, L. A., et al. Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1167-1173 DOI:10.1107/s1744309110007517 PMID:20944207 PMCID:PMC2954201
- Chiu, H. J., Bakolitsa, C., Skerra, A., Lomize, A., Carlton, D., Miller, M. D., Krishna, S. S., Abdubek, P., Astakhova, T., Axelrod, H. L., Clayton, T., Deller, M. C., et al. Structure of the first representative of pfam family pf09410 (duf2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1153-1159 DOI:10.1107/s1744309109037749 PMID:20944205 PMCID:PMC2954199
- Xu, Q. P., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X. H., Carlton, D., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., Das, D., et al. Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1354-1364 DOI:10.1107/s1744309110021214 PMID:20944232 PMCID:PMC2954226
- Bakolitsa, C., Kumar, A., Jin, K. K., McMullan, D., Krishna, S. S., Miller, M. D., Abdubek, P., Acosta, C., Astakhova, T., Axelrod, H. L., Burra, P., Carlton, D., et al. Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1182-1189 DOI:10.1107/s1744309109050647 PMID:20944209 PMCID:PMC2954203
- Han, G. W., Bakolitsa, C., Miller, M. D., Kumar, A., Carlton, D., Najmanovich, R. J., Abdubek, P., Astakhova, T., Axelrod, H. L., Chen, C., Chiu, H. J., Clayton, T., et al. Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1218-1225 DOI:10.1107/s1744309109050416 PMID:20944214 PMCID:PMC2954208
- Axelrod, H. L., Das, D., Abdubek, P., Astakhova, T., Bakolitsa, C., Carlton, D., Chen, C., Chiu, H. J., Clayton, T., Deller, M. C., Duan, L. A., Ellrott, K., et al. Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved alpha plus beta core domain and an auxiliary C-terminal treble-clef zinc finger Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1335-1346 DOI:10.1107/s1744309110020166 PMID:20944230 PMCID:PMC2954224
- Das, D., Finn, R. D., Carlton, D., Miller, M. D., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., et al. The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1265-1273 DOI:10.1107/s1744309109046788 PMID:20944221 PMCID:PMC2954215
- Chiu, H. J., Abdubek, P., Astakhova, T., Axelrod, H. L., Carlton, D., Clayton, T., Das, D., Deller, M. C., Duan, L. A., Feuerhelm, J., Grant, J. C., Grzechnik, A., et al. The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1317-1325 DOI:10.1107/s1744309110021688 PMID:20944228 PMCID:PMC2954222
- Bakolitsa, C., Bateman, A., Jin, K. K., McMullan, D., Krishna, S. S., Miller, M. D., Abdubek, P., Acosta, C., Astakhova, T., Axelrod, H. L., Burra, P., Carlton, D., et al. The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45 A resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1198-1204 DOI:10.1107/s1744309109025196 PMID:20944211 PMCID:PMC2954205
- Das, D., Kozbial, P., Han, G. W., Carlton, D., Jaroszewski, L., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Chen, C., Chiu, H. J., Chiu, M., et al. The structure of KPN03535 (gi vertical bar 152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1254-1260 DOI:10.1107/s1744309109018168 PMID:20944219 PMCID:PMC2954213
- Krishna, S. S., Aravind, L., Bakolitsa, C., Caruthers, J., Carlton, D., Miller, M. D., Abdubek, P., Astakhova, T., Axelrod, H. L., Chiu, H. J., Clayton, T., Deller, M. C., et al. The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1160-1166 DOI:10.1107/s1744309110002514 PMID:20944206 PMCID:PMC2954200
- Bakolitsa, C., Kumar, A., McMullan, D., Krishna, S. S., Miller, M. D., Carlton, D., Najmanovich, R., Abdubek, P., Astakhova, T., Chiu, H. J., Clayton, T., Deller, M. C., et al. The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1211-1217 DOI:10.1107/s1744309109022684 PMID:20944213 PMCID:PMC2954207
- Das, D., Grishin, N. V., Kumar, A., Carlton, D., Bakolitsa, C., Miller, M. D., Abdubek, P., Astakhova, T., Axelrod, H. L., Burra, P., Chen, C., Chiu, H. J., et al. The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation Acta Crystallographica Section F-Structural Biology and Crystallization Communications 2010 66:1174-1181 DOI:10.1107/s1744309109022672 PMID:20944208 PMCID:PMC2954202
- Das, D., Moiani, D., Axelrod, H. L., Miller, M. D., McMullan, D., Jin, K. K., Abdubek, P., Astakhova, T., Burra, P., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair Journal of Molecular Biology 2010 397:647-663 DOI:10.1016/j.jmb.2010.01.049 PMID:20122942 PMCID:PMC2839085
- Xu, Q., Bateman, A., Finn, R. D., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Carlton, D., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., et al. Bacterial pleckstrin homology domains: A prokaryotic origin for the PH domain Journal of Molecular Biology 2010 396:31-46 DOI:10.1016/j.jmb.2009.11.006 PMID:19913036 PMCID:PMC2817789
- Xu, Q., Traag, B. A., Willemse, J., McMullan, D., Miller, M. D., Elsliger, M. A., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Carlton, D., Chen, C., et al. Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes Journal of Biological Chemistry 2009 284:25268-25279 DOI:10.1074/jbc.M109.018564 PMID:19567872 PMCID:PMC2757229
- Xu, Q. P., Carlton, D., Miller, M. D., Elsliger, M. A., Krishna, S. S., Abdubek, P., Astakhova, T., Burra, P., Chiu, H. J., Clayton, T., Deller, M. C., Duan, L., et al. Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus Journal of Molecular Biology 2009 390:686-698 DOI:10.1016/j.jmb.2009.05.023 PMID:19450606 PMCID:PMC2726009
- Wilkinson, M. B., Xiao, G., Kumar, A., LaPlant, Q., Renthal, W., Sikder, D., Kodadek, T. J., Nestler, E. J. Imipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models Journal of Neuroscience 2009 29:7820-7832 DOI:10.1523/jneurosci.0932-09.2009 PMID:19535594 PMCID:PMC2717944
- Renthal, W., Kumar, A., Xiao, G. H., Wilkinson, M., Covington, H. E., Maze, I., Sikder, D., Robison, A. J., LaPlant, Q., Dietz, D. M., Russo, S. J., Vialou, V., et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins Neuron 2009 62:335-348 DOI:10.1016/j.neuron.2009.03.026 PMID:19447090 PMCID:PMC2779727
- Das, D., Kozbial, P., Axelrod, H. L., Miller, M. D., McMullan, D., Krishna, S. S., Abdubek, P., Acosta, C., Astakbova, T., Burra, P., Carlton, D., Chen, C., et al. Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 Å resolution Proteins-Structure Function and Bioinformatics 2009 75:296-307 DOI:10.1002/prot.22360 PMID:19173316 PMCID:PMC2785455
- Suzuki, H., Forrest, A. R. R., van Nimwegen, E., Daub, C. O., Balwierz, P. J., Irvine, K. M., Lassmann, T., Ravasi, T., Hasegawa, Y., de Hoon, M. J. L., Katayama, S., Schroder, K., et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature Genetics 2009 41:553-562 DOI:10.1038/ng.375 PMID:19377474
- Xu, Q. P., Rife, C. L., Carlton, D., Miller, M. D., Krishna, S. S., Elsliger, M. A., Abdubek, P., Astakhova, T., Chiu, H. J., Clayton, T., Duan, L., Feuerhelm, J., et al. Crystal structure of a novel archaeal AAA plus ATPase SSO 1545 from Sulfolobus solfataricus Proteins-Structure Function and Bioinformatics 2009 74:1041-1049 DOI:10.1002/prot.22325 PMID:19089981 PMCID:PMC2692486
- Xu, Q. P., Sudek, S., McMullan, D., Miller, M. D., Geierstanger, B., Jones, D. H., Krishna, S. S., Spraggon, G., Bursalay, B., Abdubek, P., Acosta, C., Ambing, E., et al. Structural basis of murein peptide specificity of a γ-D-glutamyl-l-diamino acid endopeptidase Structure 2009 17:303-313 DOI:10.1016/j.str.2008.12.008 PMID:19217401 PMCID:PMC2667786
- Xu, Q. P., McMullan, D., Abdubek, P., Astakhova, T., Carlton, D., Chen, C., Chiu, H. J., Clayton, T., Das, D., Deller, M. C., Duan, L., Elsliger, M. A., et al. A structural basis for the regulatory inactivation of DnaA Journal of Molecular Biology 2009 385:368-380 DOI:10.1016/j.jmb.2008.10.059 PMID:19000695 PMCID:PMC2667141
- Das, D., Krishna, S. S., McMullan, D., Miller, M. D., Xu, Q., Abdubek, P., Acosta, C., Astakhova, T., Axelrod, H. L., Burra, P., Carlton, D., Chiu, H. J., et al. Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution Proteins-Structure Function and Bioinformatics 2009 75:264-271 DOI:10.1002/prot.22338 PMID:19127588 PMCID:PMC2674511
- Kozbial, P., Xu, Q. P., Chiu, H. J., McMullan, D., Krishna, S. S., Miller, M. D., Abdubek, P., Acosta, C., Astakhova, T., Axelrod, H. L., Carlton, D., Clayton, T., et al. Crystal structures of MW1337R and lin2004: Representatives of a novel protein family that adopt a four-helical bundle fold Proteins-Structure Function and Bioinformatics 2008 71:1589-1596 DOI:10.1002/prot.22020 PMID:18324683
- Zubieta, C., Krishna, S. S., Kapoor, M., Kozbial, P., McMullan, D., Axelrod, H. L., Miller, M. D., Abdubek, P., Ambing, E., Astakhova, T., Carlton, D., Chiu, H. J., et al. Crystal structures of two novel dye-decolorizing peroxidases reveal a β-barrel fold with a conserved heme-binding motif Proteins-Structure Function and Bioinformatics 2007 69:223-233 DOI:10.1002/prot.21550 PMID:17654545
- Zubieta, C., Joseph, R., Krishna, S. S., McMullan, D., Kapoor, M., Axelrod, H. L., Miller, M. D., Abdubek, P., Acosta, C., Astakhova, T., Carlton, D., Chiu, H. J., et al. Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA Proteins-Structure Function and Bioinformatics 2007 69:234-243 DOI:10.1002/prot.21673 PMID:17654547
- Zubieta, C., Krishna, S. S., McMullan, D., Miller, M. D., Abdubek, P., Agarwalla, S., Ambing, E., Astakhova, T., Axelrod, H. L., Carlton, D., Chiu, H. J., Clayton, T., et al. Crystal structure of homoserine o-succinyltransferase from bacillus cereus at 2.4 Å resolution Proteins-Structure Function and Bioinformatics 2007 68:999-1005 DOI:10.1002/prot.21208 PMID:17546672
- Colvis, C. M., Pollock, J. D., Goodman, R. H., Impey, S., Dunn, J., Mandel, G., Champagne, F. A., Mayford, M., Korzus, E., Kumar, A., Renthal, W., Theobald, D. E. H., et al. Epigenetic mechanisms and gene networks in the nervous system Journal of Neuroscience 2005 25:10379-10389 DOI:10.1523/jneurosci.4119-05.2005 PMID:16280577
- Wang, K., Zhou, X. R., Zhou, Z. M., Tarakji, K., Qin, J. X., Sitges, M., Shiota, T., Forudi, F., Schaub, R. G., Kumar, A., Penn, M. S., Topol, E. J., et al. Recombinant soluble p-selectin glycoprotein ligand-ig (rpsgl-ig) attenuates infarct size and myeloperoxidase activity in a canine model of ischemia-reperfusion Thrombosis and Haemostasis 2002 88:149-154 PMID:12152656
- Teng, M. H., Yin, J. Y., Vidal, R., Ghiso, J., Kumar, A., Rabenou, R., Shah, A., Jacobson, D. R., Tagoe, C., Gallo, G., Buxbaum, J. Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: A possible model for senile systemic amyloidosis Laboratory Investigation 2001 81:385-396 PMID:11310831
- Opalka, N., Tihova, M., Brugidou, C., Kumar, A., Beachy, R. N., Fauquet, C. M., Yeager, M. Structure of native and expanded sobemoviruses by electron cryo-microscopy and image reconstruction Journal of Molecular Biology 2000 303:197-211 DOI:10.1006/jmbi.2000.4043 PMID:11023786
- Buxbaum, J. N., Genega, E. M., Lazowski, P., Kumar, A., Tunick, P. A., Kronzon, I., Gallo, G. R. Infiltrative nonamyloidotic monoclonal immunoglobulin light chain cardiomyopathy: An underappreciated manifestation of plasma cell dyscrasias Cardiology 2000 93:220-228 DOI:10.1159/000007030 PMID:11025347
- Parker, D., Rivera, M., Zor, T., Henrion-Caude, A., Radhakrishnan, I., Kumar, A., Shapiro, L. H., Wright, P. E., Montminy, M., Brindle, P. K. Role of secondary structure in discrimination between constitutive and inducible activators Molecular and Cellular Biology 1999 19:5601-5607 PMID:10409749 PMCID:PMC84412
- Reddy, V. S., Giesing, H. A., Morton, R. T., Kumar, A., Post, C. B., Brooks, C. L., Johnson, J. E. Energetics of quasiequivalence: computational analysis of protein-protein interactions in icosahedral viruses Biophysical Journal 1998 74:546-558 DOI:10.1016/S0006-3495(98)77813-0 PMID:9449355 PMCID:PMC1299407
- Kumar, A., Reddy, V. S., Yusibov, V., Chipman, P. R., Hata, Y., Fita, I., Fukuyama, K., Rossmann, M. G., LoeschFries, L. S., Baker, T. S., Johnson, J. E. The structure of alfalfa mosaic virus capsid protein assembled as a T=1 icosahedral particle at 4.0-Å resolution Journal of Virology 1997 71:7911-7916 PMID:9311881 PMCID:PMC192148
- Kumar, A., Yang, Y. L., Flati, V., Der, S., Kadereit, S., Deb, A., Haque, J., Reis, L., Weissmann, C., Williams, B. R. G. Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the pkr gene: Role of irf-1 and nf-kappa b EMBO Journal 1997 16:406-416 DOI:10.1093/emboj/16.2.406 PMID:9029159 PMCID:PMC1169645
- Yusibov, V., Kumar, A., North, A., Johnson, J. E., LoeschFries, L. S. Purification, characterization, assembly and crystallization of assembled alfalfa mosaic virus coat protein expressed in escherichia coli Journal of General Virology 1996 77:567-573 DOI:10.1099/0022-1317-77-4-567 PMID:8627243
- Yang, Y. L., Reis, L. F. L., Pavlovic, J., Aguzzi, A., Schafer, R., Kumar, A., Williams, B. R. G., Aguet, M., Weissmann, C. Deficient signaling in mice devoid of double-stranded rna-dependent protein kinase EMBO Journal 1995 14:6095-6106 PMID:8557029 PMCID:PMC394734
- Tomiyama, Y., Brojer, E., Ruggeri, Z. M., Shattil, S. J., Smiltneck, J., Gorski, J., Kumar, A., Kieberemmons, T., Kunicki, T. J. A molecular model of RGD ligands. Antibody D gene segments that direct specificity for the integrin alpha IIb beta 3 Journal of Biological Chemistry 1992 267:18085-18092 PMID:1517241
- Kumar, A., Martineztarquino, C., Mariaforte, A., Kumar, P., Alarconsegovia, D., Granados, J., Pandey, J. P., Buxbaum, J., Schur, P. H. Immunoglobulin heavy-chain constant-region gene polymorphism in systemic lupus-erythematosus Arthritis and Rheumatism 1991 34:1553-1556 PMID:1684106
- Wider, G., Macura, S., Kumar, A., Ernst, R. R., Wuthrich, K. Homonuclear two-dimensional h-1-NMR of proteins - experimental procedures Journal of Magnetic Resonance 1984 56:207-234 DOI:10.1016/0022-2364(84)90099-4
- Brown, L. R., Braun, W., Kumar, A., Wuthrich, K. High-resolution nuclear magnetic-resonance studies of the conformation and orientation of melittin bound to a lipid-water interface Biophysical Journal 1982 37:319-328 DOI:10.1016/S0006-3495(82)84680-8 PMID:6275926 PMCID:PMC1329145
- Kumar, A., Wagner, G., Ernst, R. R., Wuthrich, K. Buildup rates of the nuclear overhauser effect measured by two-dimensional proton magnetic-resonance spectroscopy - implications for studies of protein conformation Journal of the American Chemical Society 1981 103:3654-3658 DOI:10.1021/ja00403a008
- Bosch, C., Kumar, A., Baumann, R., Ernst, R. R., Wuthrich, K. Comparison of selective proton-proton overhauser effects in biological macromolecules observed by one-dimensional and two-dimensional NMR experiments Journal of Magnetic Resonance 1981 42:159-163 DOI:10.1016/0022-2364(81)90021-4
- Steinmetz, W. E., Moonen, C., Kumar, A., Lazdunski, M., Visser, L., Carlsson, F. H. H., Wuthrich, K. H-1-NMR studies of the conformation of cardiotoxin vii2 from naja-mossambica-mossambica European Journal of Biochemistry 1981 120:467-475 DOI:10.1111/j.1432-1033.1981.tb05725.x PMID:7333275
- Baumann, R., Kumar, A., Ernst, R. R., Wuthrich, K. Improvement of 2d noe and 2d correlated spectra by triangular multiplication Journal of Magnetic Resonance 1981 44:76-83 DOI:10.1016/0022-2364(81)90190-6
- Wagner, G., Kumar, A., Wuthrich, K. Systematic application of two-dimensional h-1-NMR techniques for studies of proteins .2. Combined use of correlated spectroscopy and nuclear overhauser spectroscopy for sequential assignments of backbone resonances and elucidation of polypeptide secondary structures European Journal of Biochemistry 1981 114:375-384 DOI:10.1111/j.1432-1033.1981.tb05157.x PMID:6163631
- Kumar, A., Ernst, R. R., Wuthrich, K. A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules Biochemical and Biophysical Research Communications 1980 95:1-6 DOI:10.1016/0006-291x(80)90695-6 PMID:7417242
- Nagayama, K., Kumar, A., Wuthrich, K., Ernst, R. R. Experimental-techniques of two-dimensional correlated spectroscopy Journal of Magnetic Resonance 1980 40:321-334 DOI:10.1016/0022-2364(80)90255-3
- Kumar, A., Wagner, G., Ernst, R. R., Wuthrich, K. Studies of j-connectivities and selective h-1-h-1 overhauser effects in h2o solutions of biological macromolecules by two-dimensional NMR experiments Biochemical and Biophysical Research Communications 1980 96:1156-1163 DOI:10.1016/0006-291x(80)90073-x PMID:6159893