articles
- A G protein signaling-biased agonist at the μ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal. 45:416-425. 2020
- A roadmap for development of neuro-oscillations as translational biomarkers for treatment development in neuropsychopharmacology 2020
- Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food. 45:579-588. 2020
- Promoting activity of (α4)3(β2)2 nicotinic cholinergic receptors reduces ethanol consumption. 45:301-308. 2020
- Conjugate vaccine produces long-lasting attenuation of fentanyl vs. food choice and blocks expression of opioid withdrawal-induced increases in fentanyl choice in rats. 44:1681-1689. 2019
- Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors. 44:642-653. 2019
- Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion. 44:939-949. 2019
- Synaptic adaptations in the central amygdala and hypothalamic paraventricular nucleus associated with protracted ethanol abstinence in male rhesus monkeys. 44:982-993. 2019
- Unique treatment potential of cannabidiol for the prevention of relapse to drug use. 44:229-229. 2019
- Clinical and preclinical evidence for functional interactions of cannabidiol and Δ9-tetrahydrocannabinol. 43:142-154. 2018
- Compulsive-like sufentanil vapor self-administration in rats. 43:801-809. 2018
- Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake. 43:1840-1850. 2018
- Dynorphin counteracts orexin in the paraventricular nucleus of the thalamus: cellular and behavioral evidence. 43:1010-1020. 2018
- Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats. 43:2373-2382. 2018
- Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle. 43:2036-2045. 2018
- Dissecting suicidality using a combined genomic and clinical approach. 42:360-361. 2017
- Genetic deletion of the nociceptin/orphanin FQ receptor in the rat confers resilience to the development of drug addiction. 42:695-706. 2017
- High-frequency stimulation of the subthalamic nucleus blocks compulsive-like re-escalation of heroin taking in rats. 42:1850-1859. 2017
- 5-HT1A autoreceptors in the dorsal raphe nucleus convey vulnerability to compulsive cocaine seeking. 41:1210-1222. 2016
- Double dissociation of monoacylglycerol lipase inhibition and CB1 antagonism in the central amygdala, basolateral amygdala, and the interoceptive insular cortex on the affective properties of acute naloxone-precipitated morphine withdrawal in rats. 41:1865-1873. 2016
- Dynorphin, Dysphoria, and Dependence: the Stress of Addiction. 41:373-374. 2016
- Locomotor Stimulant and Rewarding Effects of Inhaling Methamphetamine, MDPV, and Mephedrone via Electronic Cigarette-Type Technology. 41:2759-2771. 2016
- Compulsive-like responding for opioid analgesics in rats with extended access. 40:421-428. 2015
- Hypocretin receptor 2 antagonism dose-dependently reduces escalated heroin self-administration in rats. 40:1123-1129. 2015
- Pharmacological selectivity within class I histone deacetylases predicts effects on synaptic function and memory rescue. 40:2307-2316. 2015
- Transient receptor potential vanilloid type 1 channel may modulate opioid reward. 39:2414-2422. 2014
- Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat. 39:2601-2610. 2014
- Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling. 39:1763-1776. 2014
- Nociceptin/orphanin FQ decreases glutamate transmission and blocks ethanol-induced effects in the central amygdala of naive and ethanol-dependent rats. 39:1081-1092. 2014
- Phosphodiesterase 10A regulates alcohol and saccharin self-administration in rats. 39:1722-1731. 2014
- The development and maintenance of drug addiction. 39:254-262. 2014
- Inactivation of JAK2/STAT3 Signaling Axis and Downregulation of M1 mAChR Cause Cognitive Impairment in klotho Mutant Mice, a Genetic Model of Aging. 38:1426-1437. 2013
- Adenovirus capsid-based anti-cocaine vaccine prevents cocaine from binding to the nonhuman primate CNS dopamine transporter. 38:2170-2178. 2013
- Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. 38:1039-1049. 2013
- Ghrelin increases gabaergic transmission and interacts with ethanol actions in the rat central nucleus of the amygdala. 38:364-375. 2013
- Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs. 38:198-211. 2013
- Rimonabant precipitates anxiety in rats withdrawn from palatable food: role of the central amygdala. 38:2498-2507. 2013
- The NK1 receptor antagonist l822429 reduces heroin reinforcement. 38:976-984. 2013
- The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. 38:574-584. 2013
- A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults. 37:1689-1698. 2012
- Levels of neural progenitors in the hippocampus predict memory impairment and relapse to drug seeking as a function of excessive methamphetamine self-administration. 37:1275-1287. 2012
- Novel cocaine vaccine linked to a disrupted adenovirus gene transfer vector blocks cocaine psychostimulant and reinforcing effects. 37:1083-1091. 2012
- R7BP modulates opiate analgesia and tolerance but not withdrawal. 37:1005-1012. 2012
- Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence. 37:2153-2160. 2012
- Activation of σ-receptors induces binge-like drinking in Sardinian alcohol-preferring rats. 36:1207-1218. 2011
- Enhanced sensitivity to attenuation of conditioned reinstatement by the mGluR 2/3 agonist LY379268 and increased functional activity of mGluR 2/3 in rats with a history of ethanol dependence. 36:2762-2773. 2011
- Genetic association of recovery from eating disorders: The role of gaba receptor snps. 36:2222-2232. 2011
- Convergent functional genomics: what we have learned and can learn about genes, pathways, and mechanisms. 35:355-356. 2010
- Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. 35:1761-1774. 2010
- FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration. 35:1775-1787. 2010
- Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease. 35:870-880. 2010
- Neurocircuitry of addiction. 35:217-238. 2010
- R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine. 35:1040-1050. 2010
- The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala. 35:1962-1972. 2010
- Antidepressants influence somatostatin levels and receptor pharmacology in brain. 34:952-963. 2009
- Nmda receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: Role of the ventral tegmental area and central nucleus of the amygdala. 34:266-281. 2009
- Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of schizophrenia. 34:1659-1672. 2009
- The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking. 34:1482-1493. 2009
- Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB(1) antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala. 33:2483-2493. 2008
- Disruption of the CRF(2) receptor pathway decreases the somatic expression of opiate withdrawal. 33:2878-2887. 2008
- Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments. 33:2474-2482. 2008
- Gene-by-environment (serotonin transporter and childhood maltreatment) interaction for anxiety sensitivity, an intermediate phenotype for anxiety disorders. 33:312-319. 2008
- Genetic regulation of behavioral and neuronal responses to fluoxetine. 33:1312-1322. 2008
- Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food. 33:524-535. 2008
- Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. 33:643-652. 2008
- Rats with extended access to cocaine exhibit increased stress reactivity and sensitivity to the anxiolytic-like effects of the mGluR 2/3 agonist LY379268 during abstinence. 33:1818-1826. 2008
- The dorsal subiculum mediates the acquisition of conditioned reinstatement of cocaine-seeking. 33:1827-1834. 2008
- Behavioral and neurochemical responses to cocaine in periadolescent and adult rats. 32:625-637. 2007
- Delayed satiety-like actions and altered feeding microstructure by a selective type 2 corticotropin-releasing factor agonist in rats: Intra-hypothalamic urocortin 3 administration reduces food intake by prolonging the post-meal interval. 32:1052-1068. 2007
- Differential effects of sigma(1) receptor blockade on self-administration and conditioned reinstatement motivated by cocaine vs natural reward. 32:1967-1973. 2007
- Effect of aripiprazole, a partial dopamine d-2 receptor agonist, on increased rate of methamphetamine self-administration in rats with prolonged session duration. 32:2238-2247. 2007
- Fg 7142 specifically reduces meal size and the rate and regularity of sustained feeding in female rats: Evidence that benzodiazepine inverse agonists reduce food palatability. 32:1069-1081. 2007
- Impact of ambient temperature on hyperthermia induced by (+/-)3,4-methylenedioxymethamphetamine in rhesus macaques. 32:673-681. 2007
- Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task. 32:1032-1041. 2007
- Role of endocannabinoids in alcohol consumption and intoxication: Studies of mice lacking fatty acid amide hydrolase. 32:1570-1582. 2007
- Subchronic cannabinoid agonist (WIN 55,212-2) treatment during cocaine abstinence alters subsequent cocaine seeking behavior. 32:2260-2266. 2007
- A reduced rate of in vivo dopamine transporter binding is associated with lower relative reinforcing efficacy of stimulants. 31:351-362. 2006
- Big dynorphin, a prodynorphin-derived peptide produces nmda receptor-mediated effects on memory, anxiolytic-like and locomotor behavior in mice. 31:1928-1937. 2006
- Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway. 31:804-813. 2006
- Chronic ethanol exposure and protracted abstinence alter nmda receptors in central amygdala. 31:988-996. 2006
- Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice. 31:1733-1744. 2006
- Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity. 31:1203-1211. 2006
- Unlimited access to heroin self-administration: Independent motivational markers of opiate dependence. 31:2692-2707. 2006
- Buprenorphine and a crf1 antagonist block the acquisition of opiate withdrawal-induced conditioned place aversion in rats. 30:90-98. 2005
- Comt polymorphisms and anxiety-related personality traits. 30:2092-2102. 2005
- Modeling human methamphetamine exposure in nonhuman primates: chronic dosing in the rhesus macaque leads to behavioral and physiological abnormalities. 30:350-359. 2005
- Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. 30:497-507. 2005
- Presynaptic modulation of spontaneous inhibitory postsynaptic currents by gamma-hydroxybutyrate in the substantia nigra pars compacta. 29:537-543. 2004
- Previous exposure to psychostimulants enhances the reinstatement of cocaine seeking by nucleus Accumbens AMPA. 29:2149-2159. 2004
- Effects of naltrexone alone and in combination with acamprosate on the alcohol deprivation effect in rats. 28:1463-1471. 2003
- Inhibition of 5-ht neurotransmission increases clonidine protective effects on naloxone-induced conditioned place aversion in morphine-dependent rats. 28:276-283. 2003
- Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in an NMDA, AMPA/kainate, and metabotropic glutamate receptor-dependent manner. 28:629-639. 2003
- A pharmacokinetic and pharmacodynamic drug interaction study of acamprosate and naltrexone. 27:596-606. 2002
- Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge. 27:993-1005. 2002
- Conditioned opioid withdrawal decreases nociceptin/orphanin cortex and olfactory fq levels in the frontal cortex and olfactory tubercle. 27:203-211. 2002
- Effect of bilateral 6-hydroxydopamine lesions of the medial forebrain bundle on reaction time. 26:756-764. 2002
- Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats. 27:391-399. 2002
- Gamma-hydroxybutyrate reduces gaba(a)-mediated inhibitory postsynaptic potentials in the ca1 region of hippocampus. 27:960-969. 2002
- Involvement of the sigma(1) receptor in cocaine-induced conditioned place preference: Possible dependence on dopamine uptake blockade. 26:444-455. 2002
- Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in a D1 dopamine receptor dependent manner. 27:970-979. 2002
- Extended radioligand binding profile of iloperidone: A broad spectrum dopamine/serotonin/norepinephrine receptor antagonist for the management of psychotic disorders. 25:904-914. 2001
- Anxiogenic-like effects limit rewarding effects of cocaine in balb/cbyj mice. 24:300-318. 2001
- Dopamine partial agonist reverses amphetamine withdrawal in rats. 25:789-792. 2001
- Drug addiction, dysregulation of reward, and allostasis. 24:97-129. 2001
- Enduring resistance to extinction of cocaine-seeking behavior induced by drug-related cues. 25:361-372. 2001
- Functional consequences of repeated (+/-)3,4-methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys. 24:230-239. 2001
- Opiate withdrawal-induced fos immunoreactivity in the rat extended amygdala parallels the development of conditioned place aversion. 24:152-160. 2001
- Behavioral effects of central administration of the novel crf antagonist astressin in rats. 22:230-239. 2000
- Excessive ethanol drinking following a history of dependence: Animal model of allostasis. 22:581-594. 2000
- N-[1-(2-benzo[b]thiophenyl)Cyclohexyl]- piperidine (BTCP) exerts cocaine-like actions on drug-maintained responding in rats. 23:316-325. 2000
- Persistent increase in the motivation to take heroin in rats with a history of drug escalation. 22:413-421. 2000
- Reinstatement of alcohol-seeking behavior by drug-associated discriminative stimuli after prolonged extinction in the rat. 20:471-479. 1999
- Chronic acamprosate eliminates the alcohol deprivation effect while having limited effects on baseline responding for ethanol in rats. 18:125-133. 1998
- Clonidine blocks acquisition but not expression of conditioned opiate withdrawal in rats. 19:406-416. 1998
- Determinants of P3 amplitude and response to alcohol in Native American Mission Indians. 18:282-292. 1998
- Neurobiological similarities in depression and drug dependence: A self-medication hypothesis. 18:135-174. 1998
- Electrophysiological actions of neuropeptide Y and its analogs: New measures for anxiolytic therapy?. 17:34-43. 1997
- Antistress action of a corticotropin-releasing factor antagonist on behavioral reactivity to stressors of varying type and intensity. 11:179-186. 1994
- Anxiolytic-like action of neuropeptide-y - mediation by y1 receptors in amygdala, and dissociation from food-intake effects. 8:357-363. 1993
- Lisuride reduces psychomotor retardation during withdrawal from chronic intravenous amphetamine self-administration in rats. 8:213-218. 1993
- Rapid induction of conditioned opiate withdrawal in the rat. 8:15-21. 1993
- Selective effects of low-dose d2-dopamine receptor antagonism in a reaction-time-task in rats. 8:195-200. 1993
- Bromocriptine reverses the elevation in intracranial self-stimulation thresholds observed in a rat model of cocaine withdrawal. 7:213-224. 1992
- Endocrine, immune, and neurochemical changes in rats during withdrawal from chronic amphetamine intoxication. 5:23-31. 1991
- Evaluation of EEG alpha-activity in sons of alcoholics. 4:199-205. 1991
- Nonlinear-analysis of EEG sleep states. 5:167-176. 1991
- Postcocaine anhedonia: an animal model of cocaine withdrawal. 4:17-26. 1991
- Bromocriptine produces decreases in cocaine self-administration in the rat. 3:101-108. 1990
- Potentiation of acoustic startle by corticotropin-releasing factor (crf) and by fear are both reversed by alpha-helical crf (9-41). 2:285-292. 1989