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Accessory mutations maintain stability in drug-resistant HIV-1 protease

Academic Article
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Overview

authors

  • Chang, M. W.
  • Torbett, Bruce

publication date

  • July 2011

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Calorimetry, Differential Scanning
  • Drug Resistance, Viral
  • Enzyme Stability
  • HIV Protease
  • HIV Protease Inhibitors
  • HIV-1
  • Humans
  • Hydrogen-Ion Concentration
  • Mutant Proteins
  • Mutation
  • Protein Multimerization
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Research

keywords

  • HIV protease
  • differential scanning calorimetry
  • drug resistance
  • protein stability
  • viral evolution
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Identity

PubMed Central ID

  • PMC3139113

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1016/j.jmb.2011.03.038

PubMed ID

  • 21762813
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Additional Document Info

start page

  • 756

end page

  • 760

volume

  • 410

issue

  • 4

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