recent publications

• academic article

  • Becker, C. F. W., Strop, P., Bass, R. B., Hansen, K. C., Locher, K. P., Ren, G., Yeager, M., Rees, D. C., Kochendoerfer, G. G. Conversion of a mechanosensitive channel protein from a membrane-embedded to a water-soluble form by covalent modification with amphiphiles Journal of Molecular Biology  2004 343:747-758  DOI:10.1016/j.jmb.2004.08.062  PMID:15465059
  • Kielkopf, C. L., Kuhn, P., Rees, D. C., Ding, S. Conformational flexibility of b-DNA at 0.74 Å resolution: D(ccagtactgg)(2) Journal of Molecular Biology  2000 296:787-801  DOI:10.1006/jmbi.1999.3478  PMID:10677281
  • Yeh, A. P., Chatelet, C., Soltis, S. M., Kuhn, P., Meyer, J., Rees, D. C. Structure of a thioredoxin-like 2fe-2s ferredoxin from aquifex aeolicus Journal of Molecular Biology  2000 300:587-595  DOI:10.1006/jmbi.2000.3871  PMID:10884354
  • Boden, P. R., Higginbottom, M., Hill, D. R., Horwell, D. C., Hughes, J., Rees, D. C., Roberts, E., Singh, L., Sumanchauhan, N., Woodruff, G. N. Cholecystokinin dipeptoid antagonists: Design, synthesis, and anxiolytic profile of some novel cck-a and cck-b selective and "mixed" cck-a/cck-b antagonists Journal of Medicinal Chemistry  1993 36:552-565  DOI:10.1021/jm00057a005  PMID:7684452
  • Higginbottom, M., Nolan, W., Otoole, J., Ratcliffe, G. S., Rees, D. C., Roberts, E. The design and synthesis of kappa-opioid ligands based on a binding model for kappa agonists Bioorganic & Medicinal Chemistry Letters  1993 3:841-846  DOI:10.1016/s0960-894x(00)80677-0
  • Fincham, C. I., Higginbottom, M., Hill, D. R., Horwell, D. C., Otoole, J. C., Ratcliffe, G. S., Rees, D. C., Roberts, E. Amide bond replacements incorporated into cck-b selective "dipeptoids" Journal of Medicinal Chemistry  1992 35:1472-1484  DOI:10.1021/jm00086a017  PMID:1573640