recent publications

• academic article

  • Whitfield, T., Miles, A. J., Scheinost, J. C., Offer, J., Wentworth, P., Dwek, R. A., Wallace, B. A., Biggin, P. C., Zitzmann, N. The influence of different lipid environments on the structure and function of the hepatitis c virus p7 ion channel protein Molecular Membrane Biology  2011 28:254-264  DOI:10.3109/09687688.2011.581253  PMID:21604991
  • Cole, M. A., Tully, S. E., Dodds, A. W., Arnold, J. N., Boldt, G. E., Sim, R. B., Offer, J., Wentworth, P. A chemical approach to immunoprotein engineering: Chemoselective functionalization of thioester proteins in their native state ChemBioChem  2009 10:1340-1343  DOI:10.1002/cbic.200900168  PMID:19402090
  • Scheinost, J. C., Witter, D. P., Boldt, G. E., Offer, J., Wentworth, P. Cholesterol secosterol adduction inhibits the misfolding of a mutant prion protein fragment that induces neurodegeneration Angewandte Chemie-International Edition  2009 48:9469-9472  DOI:10.1002/anie.200904524  PMID:19899085  PMCID:PMC2837945
  • Scheinost, J. C., Wang, H., Boldt, G. E., Offer, J., Wentworth, P. Cholesterol seco-sterol-induced aggregation of methylated amyloid-β peptides - insights into aldehyde-initiated fibrillization of amyloid-β Angewandte Chemie-International Edition  2008 47:3919-3922  DOI:10.1002/anie.200705922  PMID:18404766
  • Burlina, F., Dixson, D. D., Doyle, R. P., Chassaing, G., Boddy, C. N., Dawson, P., Offer, J. Orthogonal ligation: a three piece assembly of a PNA-peptide-PNA conjugate Chemical Communications  2008 2785-2787  DOI:10.1039/b801242c  PMID:18688310
  • Marinzi, C., Offer, J., Longhi, R., Dawson, P. E. An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications Bioorganic & Medicinal Chemistry  2004 12:2749-2757  DOI:10.1016/j.bmc.2004.02.039  PMID:15110856
  • Moss, J. A., Coyle, A. R., Ahn, J. M., Meijler, M. M., Offer, J., Janda, K. D. Tandem IMAC-HPLC purification of a cocaine-binding scFv antibody Journal of Immunological Methods  2003 281:143-148  DOI:10.1016/j.jim.2003.07.010  PMID:14580888
  • Offer, J., Boddy, C. N. C., Dawson, P. E. Extending synthetic access to proteins with a removable acyl transfer auxiliary Journal of the American Chemical Society  2002 124:4642-4646  DOI:10.1021/ja016731w  PMID:11971712
  • Marinzi, C., Bark, S. J., Offer, J., Dawson, P. E. A new scaffold for amide ligation Bioorganic & Medicinal Chemistry  2001 9:2323-2328  DOI:10.1016/s0968-0896(01)00136-5  PMID:11553471
  • Offer, J., Dawson, P. E. N-alpha-2-mercaptobenzylamine-assisted chemical ligation Organic Letters  2000 2:23-26  DOI:10.1021/ol991184t  PMID:10814236