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Chou, C. J.

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    • Soragni, E., Chou, C. J., Rusche, J. R., Gottesfeld, J. M. Mechanism of action of 2-aminobenzamide HDAC inhibitors in reversing gene silencing in Friedreich's ataxia Frontiers in Neurology  2015 6:44  DOI:10.3389/fneur.2015.00044  PMID:25798128  PMCID:PMC4350406
    • Jespersen, C., Soragni, E., Chou, C. J., Arora, P. S., Dervan, P. B., Gottesfeld, J. M. Chromatin structure determines accessibility of a hairpin polyamide-chlorambucil conjugate at histone H4 genes in pancreatic cancer cells Bioorganic & Medicinal Chemistry Letters  2012 22:4068-4071  DOI:10.1016/j.bmcl.2012.04.090  PMID:22607671  PMCID:PMC3362666
    • Rai, M., Soragni, E., Chou, C. J., Barnes, G., Jones, S., Rusche, J. R., Gottesfeld, J. M., Pandolfo, M. Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model PLoS One  2010 5:e8825  DOI:10.1371/journal.pone.0008825  PMID:20098685  PMCID:PMC2809102
    • Xu, C. P., Soragni, E., Chou, C. J., Herman, D., Plasterer, H. L., Rusche, J. R., Gottesfeld, J. M. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing Chemistry & Biology  2009 16:980-989  DOI:10.1016/j.chembiol.2009.07.010  PMID:19778726  PMCID:PMC2909763
    • Hu, F., Chou, C. J., Gottesfeld, J. M. Design and synthesis of novel hybrid benzamide-peptide histone deacetylase inhibitors Bioorganic & Medicinal Chemistry Letters  2009 19:3928-3931  DOI:10.1016/j.bmcl.2009.03.085  PMID:19362838  PMCID:PMC3045849
    • Chou, C. J., Herman, D., Gottesfeld, J. M. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class i histone deacetylases Journal of Biological Chemistry  2008 283:35402-35409  DOI:10.1074/jbc.M807045200  PMID:18953021  PMCID:PMC2602898
    • Chou, C. J., O'Hare, T., Lefebvre, S., Alvarez, D., Tyner, J. W., Eide, C. A., Druker, B. J., Gottesfeld, J. M. Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate PLoS One  2008 3:e3593  DOI:10.1371/journal.pone.0003593  PMID:18974832  PMCID:PMC2571993
    • Chou, C. J., Farkas, M. E., Tsai, S. M., Alvarez, D., Dervan, P. B., Gottesfeld, J. M. Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia Molecular Cancer Therapeutics  2008 7:769-778  DOI:10.1158/1535-7163.mct-08-0130  PMID:18413791  PMCID:PMC2376757
    • Tsai, S. M., Farkas, M. E., Chou, C. J., Gottesfeld, J. M., Dervan, P. B. Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates Nucleic Acids Research  2007 35:307-316  DOI:10.1093/nar/gkl1025  PMID:17170006  PMCID:PMC1802559
    • Alvarez, D., Chou, C. J., Latella, L., Zeitlin, S. G., Ku, S., Puri, P. L., Dervan, P. B., Gottesfeld, J. M. A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate Cell Cycle  2006 5:1537-1548  DOI:10.4161/cc.5.14.2913  PMID:16861886

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