recent publications
-
academic article
- Chen, L. M., Blixt, O., Stevens, J., Lipatov, A. S., Davis, C. T., Collins, B. E., Cox, N. J., Paulson, J. C., Donis, R. O. In vitro evolution of h5n1 avian influenza virus toward human-type receptor specificity Virology 2012 422:105-113 DOI:10.1016/j.virol.2011.10.006 PMID:22056389
- Maines, T. R., Chen, L. M., Van Hoeven, N., Tumpey, T. M., Blixt, O., Belser, J. A., Gustin, K. M., Pearce, M. B., Pappas, C., Stevens, J., Cox, N. J., Paulson, J. C., et al. Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza h5n1 viruses Virology 2011 413:139-147 DOI:10.1016/j.virol.2011.02.015 PMID:21397290
- Astronomo, R. D., Lee, H. K., Scanlan, C. N., Pantophlet, R., Huang, C. Y., Wilson, I. A., Blixt, O., Dwek, R. A., Wong, C. H., Burton, D. R. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2g12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120 Journal of Virology 2008 82:6359-6368 DOI:10.1128/jvi.00293-08 PMID:18434393 PMCID:PMC2447108
- Belser, J. A., Blixt, O., Chen, L. M., Pappas, C., Maines, T. R., Van Hoeven, N., Donis, R., Busch, J., McBride, R., Paulson, J. C., Katz, J. M., Tumpey, T. M. Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility Proceedings of the National Academy of Sciences of the United States of America 2008 105:7558-7563 DOI:10.1073/pnas.0801259105 PMID:18508975 PMCID:PMC2396559
- Stevens, J., Blixt, O., Chen, L. M., Donis, R. O., Paulson, J. C., Wilson, I. A. Recent avian h5n1 viruses exhibit increased propensity for acquiring human receptor specificity Journal of Molecular Biology 2008 381:1382-1394 DOI:10.1016/j.jmb.2008.04.016 PMID:18672252 PMCID:PMC2519951
- Blixt, O., Han, S. F., Liao, L., Zeng, Y., Hoffmann, J., Futakawa, S., Paulson, J. C. Sialoside analogue arrays for rapid identification of high affinity siglec ligands Journal of the American Chemical Society 2008 130:6680-6681 DOI:10.1021/ja80l052g PMID:18452295 PMCID:PMC2614358
- Kaltgrad, E., Sen Gupta, S., Punna, S., Huang, C. Y., Chang, A., Wong, C. H., Finn, M. G., Blixt, O. Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold ChemBioChem 2007 8:1455-1462 DOI:10.1002/cbic.200700225 PMID:17676704
- Stevens, J., Blixt, O., Glaser, L., Taubenberger, J. K., Palese, P., Paulson, J. C., Wilson, I. A. Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities Journal of Molecular Biology 2006 355:1143-1155 DOI:10.1016/j.jmb.2005.11.002 PMID:16343533
- Stevens, J., Blixt, O., Paulson, J. C., Wilson, I. A. Glycan microarray technologies: Tools to survey host specificity of influenza viruses Nature Reviews Microbiology 2006 4:857-864 DOI:10.1038/nrmicro1530 PMID:17013397
- Collins, B. E., Blixt, O., Han, S. F., Duong, B., Li, H. Y., Nathan, J. K., Bovin, N., Paulson, J. C. High-affinity ligand probes of cd22 overcome the threshold set by cis ligands for binding, endocytosis, and killing of b cells Journal of Immunology 2006 177:2994-3003 PMID:16920935
- Stevens, J., Blixt, O., Tumpey, T. M., Taubenberger, J. K., Paulson, J. C., Wilson, I. A. Structure and receptor specificity of the hemagglutinin from an h5n1 influenza virus Science 2006 312:404-410 DOI:10.1126/science.1124513 PMID:16543414
- Paulson, J. C., Blixt, O., Collins, B. E. Sweet spots in functional glycomics Nature Chemical Biology 2006 2:238-248 DOI:10.1038/nchembio785 PMID:16619023
- Blixt, O., Vasiliu, D., Allin, K., Jacobsen, N., Warnock, D., Razi, N., Paulson, J. C., Bernatchez, S., Gilbert, M., Wakarchuk, W. Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides gd3, gt3, gm2, gd2, gt2, gm1, and gd1a Carbohydrate Research 2005 340:1963-1972 DOI:10.1016/j.carres.2005.06.008 PMID:16005859
- Vyas, A. A., Blixt, O., Paulson, J. C., Schnaar, R. L. Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro Journal of Biological Chemistry 2005 280:16305-16310 DOI:10.1074/jbc.M500250200 PMID:15701648 PMCID:PMC1852507
- Shen, Z. X., Go, E. P., Gamez, A., Apon, J. V., Fokin, V., Greig, M., Ventura, M., Crowell, J. E., Blixt, O., Paulson, J. C., Stevens, R. C., Finn, M. G., et al. A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a desorption/ionization on silicon (DIOS) platform ChemBioChem 2004 5:921-927 DOI:10.1002/cbic.200400008 PMID:15239048
- Collins, B. E., Blixt, O., DeSieno, A. R., Bovin, N., Marth, J. D., Paulson, J. C. Masking of cd22 by cis ligands does not prevent redistribution of cd22 to sites of cell contact Proceedings of the National Academy of Sciences of the United States of America 2004 101:6104-6109 DOI:10.1073/pnas.0400851101 PMID:15079087 PMCID:PMC395930
- Blixt, O., Head, S., Mondala, T., Scanlan, C., Huflejt, M. E., Alvarez, R., Bryan, M. C., Fazio, F., Calarese, D., Stevens, J., Razi, N., Stevens, D. J., et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins Proceedings of the National Academy of Sciences of the United States of America 2004 101:17033-17038 DOI:10.1073/pnas.0407902101 PMID:15563589 PMCID:PMC534418
- Blixt, O., Paulson, J. C. Biocatalytic preparation of n-glycolylneuraminic acid, deaminoneuraminic acid (kdn) and 9-azido-9-deoxysialic acid oligosaccharides Advanced Synthesis & Catalysis 2003 345:687-690 DOI:10.1002/adsc.200303032
- Blixt, O., Collins, B. E., van den Nieuwenhof, I. M., Crocker, P. R., Paulson, J. C. Sialoside specificity of the siglec family assessed using novel multivalent probes - identification of potent inhibitors of myelin-associated glycoprotein Journal of Biological Chemistry 2003 278:31007-31019 DOI:10.1074/jbc.M304331200 PMID:12773526
- Kalovidouris, S. A., Blixt, O., Nelson, A., Vidal, S., Turnbull, W. B., Paulson, J. C., Stoddart, J. F. Synthetic carbohydrate dendrimers, part 11. Chemically defined sialoside scaffolds for investigation of multivalent interactions with sialic acid binding proteins Journal of Organic Chemistry 2003 68:8485-8493 DOI:10.1021/jo030203g PMID:14575475
- Danzer, C. P., Collins, B. E., Blixt, O., Paulson, J. C., Nitschke, L. Transitional and marginal zone b cells have a high proportion of unmasked cd22: Implications for bcr signaling International Immunology 2003 15:1137-1147 DOI:10.1093/intimm/dxg114 PMID:13679384
- Collins, B. E., Blixt, O., Bovin, N. V., Danzer, C. P., Chui, D., Marth, J. D., Nitschke, L., Paulson, J. C. Constitutively unmasked cd22 on b cells of st6gal i knockout mice: Novel sialoside probe for murine cd22 Glycobiology 2002 12:563-571 DOI:10.1093/glycob/cwf067 PMID:12213789
- Blixt, O., Allin, K., Pereira, L., Datta, A., Paulson, J. C. Efficient chemoenzymatic synthesis of o-linked sialyl oligosaccharides Journal of the American Chemical Society 2002 124:5739-5746 DOI:10.1021/ja017881+ PMID:12010048
- Lee, K. J., Mao, S. L., Sun, C. Z., Gao, C., Blixt, O., Arrues, S., Hom, L. G., Kaufmann, G. F., Hoffman, T. Z., Coyle, A. R., Paulson, J., Felding-Habermann, B., et al. Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen Journal of the American Chemical Society 2002 124:12439-12446 DOI:10.1021/ja020737j PMID:12381184
- Dormitzer, P. R., Sun, Z. Y. J., Blixt, O., Paulson, J. C., Wagner, G., Harrison, S. C. Specificity and affinity of sialic acid binding by the rhesus rotavirus vp8*core Journal of Virology 2002 76:10512-10517 DOI:10.1128/jvi.76.20.10512-10517.2002 PMID:12239329
- Fazio, F., Bryan, M. C., Blixt, O., Paulson, J. C., Wong, C. H. Synthesis of sugar arrays in microtiter plate Journal of the American Chemical Society 2002 124:14397-14402 DOI:10.1021/ja020887u PMID:12452714
- Blixt, O., Brown, J., Schur, M. J., Wakarchuk, W., Paulson, J. C. Efficient preparation of natural and synthetic galactosides with a recombinant beta-1,4-galactosyltransferase-/udp-4 '-gal epimerase fusion protein Journal of Organic Chemistry 2001 66:2442-2448 DOI:10.1021/jo0057809 PMID:11281786