recent publications
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academic article
- Gauba, V., Grunewald, J., Gorney, V., Deaton, L. M., Kang, M. C., Bursulaya, B., Ou, W. J., Lerner, R. A., Schmedt, C., Geierstanger, B. H., Schultz, P. G., Ramirez-Montagut, T. Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids Proceedings of the National Academy of Sciences of the United States of America 2011 108:12821-12826 DOI:10.1073/pnas.1110042108 PMID:21768354 PMCID:PMC3150954
- Cellitti, S. E., Ou, W. J., Chiu, H. P., Grunewald, J., Jones, D. H., Hao, X. S., Fan, Q., Quinn, L. L., Ng, K., Anfora, A. T., Lesley, S. A., Uno, T., et al. D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine Nature Chemical Biology 2011 7:528-530 DOI:10.1038/nchembio.586 PMID:21525873
- Ou, W. J., Uno, T., Chiu, H. P., Grunewald, J., Cellitti, S. E., Crossgrove, T., Hao, X. S., Fan, Q., Quinn, L. L., Patterson, P., Okach, L., Jones, D. H., et al. Site-specific protein modifications through pyrroline-carboxy-lysine residues Proceedings of the National Academy of Sciences of the United States of America 2011 108:10437-10442 DOI:10.1073/pnas.1105197108 PMID:21670250 PMCID:PMC3127931
- Jones, D. H., Cellitti, S. E., Hao, X. S., Zhang, Q., Jahnz, M., Summerer, D., Schultz, P. G., Uno, T., Geierstanger, B. H. Site-specific labeling of proteins with NMR-active unnatural amino acids Journal of Biomolecular NMR 2010 46:89-100 DOI:10.1007/s10858-009-9365-4 PMID:19669620
- Lee, J., Hong, J. Y., Nam, T. G., Peters, E. C., Orth, A. P., Geierstanger, B. H., Goldfinger, L. E., Ginsberg, M. H., Cho, C. Y., Schultz, P. G. A small molecule inhibitor of α4 integrin-dependent cell migration Bioorganic & Medicinal Chemistry 2009 17:977-980 DOI:10.1016/j.bmc.2008.02.067 PMID:18329275 PMCID:PMC2951142
- Chen, P. R., Groff, D., Guo, J. T., Ou, W. J., Cellitti, S., Geierstanger, B. H., Schultz, P. G. A facile system for encoding unnatural amino acids in mammalian cells Angewandte Chemie-International Edition 2009 48:4052-4055 DOI:10.1002/anie.200900683 PMID:19378306 PMCID:PMC2873846
- Liu, C. C., Cellitti, S. E., Geierstanger, B. H., Schultz, P. G. Efficient expression of tyrosine-sulfated proteins in E. coli using an expanded genetic code Nature Protocols 2009 4:1784-1789 DOI:10.1038/nprot.2009.188 PMID:20010929 PMCID:PMC2928070
- Cellitti, S. E., Jones, D. H., Lagpacan, L., Hao, X. S., Zhang, Q., Hu, H. Y., Brittain, S. M., Brinker, A., Caldwell, J., Bursulaya, B., Spraggon, G., Brock, A., et al. In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy Journal of the American Chemical Society 2008 130:9268-9281 DOI:10.1021/ja801602q PMID:18576636 PMCID:PMC2562865
- Graziano, J. J., Liu, W. S., Perera, R., Geierstanger, B. H., Lesley, S. A., Schultz, P. G. Selecting folded proteins from a library of secondary structural elements Journal of the American Chemical Society 2008 130:176-185 DOI:10.1021/ja074405w PMID:18067292 PMCID:PMC2714538
- Lemke, E. A., Summerer, D., Geierstanger, B. H., Brittain, S. M., Schultz, P. G. Control of protein phosphorylation with a genetically encoded photocaged amino acid Nature Chemical Biology 2007 3:769-772 DOI:10.1038/nchembio.2007.44 PMID:17965709
- Matsuda, S., Fillo, J. D., Henry, A. A., Rai, P., Wilkens, S. J., Dwyer, T. J., Geierstanger, B. H., Wemmer, D. E., Schultz, P. G., Spraggon, G., Romesberg, F. E. Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs Journal of the American Chemical Society 2007 129:10466-10473 DOI:10.1021/ja072276d PMID:17685517 PMCID:PMC2536688
- Macpherson, L. J., Geierstanger, B. H., Viswanath, V., Bandell, M., Eid, S. R., Hwang, S., Patapoutian, A. The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin Current Biology 2005 15:929-934 DOI:10.1016/j/cub.2005.04.018 PMID:15916949
- Deiters, A., Geierstanger, B. H., Schultz, P. G. Site-specific in vivo labeling of proteins for NMR studies ChemBioChem 2005 6:55-58 DOI:10.1002/cbic.200400319 PMID:15549724
- Scott, L. G., Geierstanger, B. H., Williamson, J. R., Hennig, M. Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA Journal of the American Chemical Society 2004 126:11776-11777 DOI:10.1021/ja047556x PMID:15382896
- Henry, A. A., Olsen, A. G., Matsuda, S., Yu, C. Z., Geierstanger, B. H., Romesberg, F. E. Efforts to expand the genetic alphabet: Identification of a replicable unnatural DNA self-pair Journal of the American Chemical Society 2004 126:6923-6931 DOI:10.1021/ja049961u PMID:15174862