recent publications

• academic article

  • Gauba, V., Grunewald, J., Gorney, V., Deaton, L. M., Kang, M. C., Bursulaya, B., Ou, W. J., Lerner, R. A., Schmedt, C., Geierstanger, B. H., Schultz, P. G., Ramirez-Montagut, T. Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids Proceedings of the National Academy of Sciences of the United States of America  2011 108:12821-12826  DOI:10.1073/pnas.1110042108  PMID:21768354  PMCID:PMC3150954
  • Cellitti, S. E., Ou, W. J., Chiu, H. P., Grunewald, J., Jones, D. H., Hao, X. S., Fan, Q., Quinn, L. L., Ng, K., Anfora, A. T., Lesley, S. A., Uno, T., et al. D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine Nature Chemical Biology  2011 7:528-530  DOI:10.1038/nchembio.586  PMID:21525873
  • Ou, W. J., Uno, T., Chiu, H. P., Grunewald, J., Cellitti, S. E., Crossgrove, T., Hao, X. S., Fan, Q., Quinn, L. L., Patterson, P., Okach, L., Jones, D. H., et al. Site-specific protein modifications through pyrroline-carboxy-lysine residues Proceedings of the National Academy of Sciences of the United States of America  2011 108:10437-10442  DOI:10.1073/pnas.1105197108  PMID:21670250  PMCID:PMC3127931
  • Jones, D. H., Cellitti, S. E., Hao, X. S., Zhang, Q., Jahnz, M., Summerer, D., Schultz, P. G., Uno, T., Geierstanger, B. H. Site-specific labeling of proteins with NMR-active unnatural amino acids Journal of Biomolecular NMR  2010 46:89-100  DOI:10.1007/s10858-009-9365-4  PMID:19669620
  • Lee, J., Hong, J. Y., Nam, T. G., Peters, E. C., Orth, A. P., Geierstanger, B. H., Goldfinger, L. E., Ginsberg, M. H., Cho, C. Y., Schultz, P. G. A small molecule inhibitor of α4 integrin-dependent cell migration Bioorganic & Medicinal Chemistry  2009 17:977-980  DOI:10.1016/j.bmc.2008.02.067  PMID:18329275  PMCID:PMC2951142
  • Chen, P. R., Groff, D., Guo, J. T., Ou, W. J., Cellitti, S., Geierstanger, B. H., Schultz, P. G. A facile system for encoding unnatural amino acids in mammalian cells Angewandte Chemie-International Edition  2009 48:4052-4055  DOI:10.1002/anie.200900683  PMID:19378306  PMCID:PMC2873846
  • Liu, C. C., Cellitti, S. E., Geierstanger, B. H., Schultz, P. G. Efficient expression of tyrosine-sulfated proteins in E. coli using an expanded genetic code Nature Protocols  2009 4:1784-1789  DOI:10.1038/nprot.2009.188  PMID:20010929  PMCID:PMC2928070
  • Cellitti, S. E., Jones, D. H., Lagpacan, L., Hao, X. S., Zhang, Q., Hu, H. Y., Brittain, S. M., Brinker, A., Caldwell, J., Bursulaya, B., Spraggon, G., Brock, A., et al. In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy Journal of the American Chemical Society  2008 130:9268-9281  DOI:10.1021/ja801602q  PMID:18576636  PMCID:PMC2562865
  • Graziano, J. J., Liu, W. S., Perera, R., Geierstanger, B. H., Lesley, S. A., Schultz, P. G. Selecting folded proteins from a library of secondary structural elements Journal of the American Chemical Society  2008 130:176-185  DOI:10.1021/ja074405w  PMID:18067292  PMCID:PMC2714538
  • Lemke, E. A., Summerer, D., Geierstanger, B. H., Brittain, S. M., Schultz, P. G. Control of protein phosphorylation with a genetically encoded photocaged amino acid Nature Chemical Biology  2007 3:769-772  DOI:10.1038/nchembio.2007.44  PMID:17965709
  • Matsuda, S., Fillo, J. D., Henry, A. A., Rai, P., Wilkens, S. J., Dwyer, T. J., Geierstanger, B. H., Wemmer, D. E., Schultz, P. G., Spraggon, G., Romesberg, F. E. Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs Journal of the American Chemical Society  2007 129:10466-10473  DOI:10.1021/ja072276d  PMID:17685517  PMCID:PMC2536688
  • Macpherson, L. J., Geierstanger, B. H., Viswanath, V., Bandell, M., Eid, S. R., Hwang, S., Patapoutian, A. The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin Current Biology  2005 15:929-934  DOI:10.1016/j/cub.2005.04.018  PMID:15916949
  • Deiters, A., Geierstanger, B. H., Schultz, P. G. Site-specific in vivo labeling of proteins for NMR studies ChemBioChem  2005 6:55-58  DOI:10.1002/cbic.200400319  PMID:15549724
  • Scott, L. G., Geierstanger, B. H., Williamson, J. R., Hennig, M. Enzymatic synthesis and 19F NMR studies of 2-fluoroadenine-substituted RNA Journal of the American Chemical Society  2004 126:11776-11777  DOI:10.1021/ja047556x  PMID:15382896
  • Henry, A. A., Olsen, A. G., Matsuda, S., Yu, C. Z., Geierstanger, B. H., Romesberg, F. E. Efforts to expand the genetic alphabet: Identification of a replicable unnatural DNA self-pair Journal of the American Chemical Society  2004 126:6923-6931  DOI:10.1021/ja049961u  PMID:15174862