recent publications

• academic article

  • Beerli, R. R., Rader, C. Mining human antibody repertoires MAbs  2010 2:365-378  DOI:10.4161/mabs.2.4.12187  PMID:20505349  PMCID:PMC3180084
  • Segal, D. J., Beerli, R. R., Blancafort, P., Dreier, B., Effertz, K., Huber, A., Koksch, B., Lund, C. V., Magnenat, L., Valente, D., Barbas, C. F. Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins Biochemistry  2003 42:2137-2148  DOI:10.1021/bi026806o  PMID:12590603
  • Hyland, S., Beerli, R. R., Barbas, C. F., Hynes, N. E., Wels, W. Generation and functional characterization of intracellular antibodies interacting with the kinase domain of human egf receptor Oncogene  2003 22:1557-1567  DOI:10.1038/sj.onc.1206299  PMID:12629519
  • Jendreyko, N., Popkov, M., Beerli, R. R., Chung, J. H., McGavern, D. B., Rader, C., Barbas, C. F. Intradiabodies, bispecific, tetravalent antibodies for the simultaneous functional knockout of two cell surface receptors Journal of Biological Chemistry  2003 278:47812-47819  DOI:10.1074/jbc.M307002200  PMID:12947084
  • Holbro, T., Beerli, R. R., Maurer, F., Koziczak, M., Barbas, C. F., Hynes, N. E. The erbb2/erbb3 heterodimer functions as an oncogenic unit: Erbb2 requires erbb3 to drive breast tumor cell proliferation Proceedings of the National Academy of Sciences of the United States of America  2003 100:8933-8938  DOI:10.1073/pnas.1537685100  PMID:12853564  PMCID:PMC166416
  • Beerli, R. R., Barbas, C. F. Engineering polydactyl zinc-finger transcription factors Nature Biotechnology  2002 20:135-141  DOI:10.1038/nbt0202-135  PMID:11821858
  • Dreier, B., Beerli, R. R., Segal, D. J., Flippin, J. D., Barbas, C. F. Development of zinc finger domains for recognition of the 5 '-ann-3 ' family of DNA sequences and their use in the construction of artificial transcription factors Journal of Biological Chemistry  2001 276:29466-29478  DOI:10.1074/jbc.M102604200  PMID:11340073
  • Beerli, R. R., Schopfer, U., Dreier, B., Barbas, C. F. Chemically regulated zinc finger transcription factors Journal of Biological Chemistry  2000 275:32617-32627  DOI:10.1074/jbc.M005108200  PMID:10924515
  • Beerli, R. R., Dreier, B., Barbas, C. F. Positive and negative regulation of endogenous genes by designed transcription factors Proceedings of the National Academy of Sciences of the United States of America  2000 97:1495-1500  DOI:10.1073/pnas.040552697  PMID:10660690  PMCID:PMC26462
  • Segal, D. J., Dreier, B., Beerli, R. R., Barbas, C. F. Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5 '-gnn-3 ' DNA target sequences Proceedings of the National Academy of Sciences of the United States of America  1999 96:2758-2763  DOI:10.1073/pnas.96.6.2758  PMID:10077584
  • Beerli, R. R., Segal, D. J., Dreier, B., Barbas, C. F. Toward controlling gene expression at will: Specific regulation of the erbb-2/her-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks Proceedings of the National Academy of Sciences of the United States of America  1998 95:14628-14633  DOI:10.1073/pnas.95.25.14628  PMID:9843940