recent publications

• academic article

  • Hernandez, A. A., Roush, W. R. Recent advances in the synthesis, design and selection of cysteine protease inhibitors Current Opinion in Chemical Biology  2002 6:459-465  DOI:10.1016/s1367-5931(02)00345-9  PMID:12133721
  • Caffrey, C. R., Hansell, E., Lucas, K. D., Brinen, L. S., Hernandez, A. A., Cheng, J. N., Gwaltney, S. L., Roush, W. R., Stierhof, Y. D., Bogyo, M., Steverding, D., McKerrow, J. H. Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense Molecular and Biochemical Parasitology  2001 118:61-73  DOI:10.1016/s0166-6851(01)00368-1  PMID:11704274
  • Roush, W. R., Hernandez, A. A., McKerrow, J. H., Selzer, P. M., Hansell, E., Engel, J. C. Design, synthesis and evaluation of D-homophenylalanyl epoxysuccinate inhibitors of the trypanosomal cysteine protease cruzain Tetrahedron  2000 56:9747-9762  DOI:10.1016/s0040-4020(00)00882-6
  • Roush, W. R., Hernandez, A. A., Zepeda, G. A new synthesis of peptidyl epoxysuccinates for probing cysteine protease-inhibitor p-3/s-3 binding interactions Synthesis-Stuttgart  1999 1999:1500-1504  DOI:10.1055/s-1999-3648