Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form

Promotion and prevention of autoimmunity by b-lymphocytes

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Nemazee, David

publication date

  • December 1993

journal

  • Current Opinion in Immunology  Journal

abstract

  • B lymphocytes are normally subject to heavy and ongoing selection through their antigen-specific Ig receptors. Self tolerance mediated through antigen-receptor crosslinking on B cells appears to function in a variety of different and perhaps complementary ways, leading to cell death or editing of the antigen-receptor genes. The consequences of defects in these processes are unclear, but may be sufficient to explain systemic autoimmune disease.

subject areas

  • Animals
  • Autoimmune Diseases
  • Autoimmunity
  • B-Lymphocytes
  • Humans
  • Immune Tolerance
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0952-7915

Digital Object Identifier (DOI)

  • 10.1016/0952-7915(93)90098-d

PubMed ID

  • 8297518
scroll to property group menus

Additional Document Info

start page

  • 866

end page

  • 872

volume

  • 5

issue

  • 6

©2021 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support