recent publications

• academic article

  • Dinev, D., Jordan, B. W. A., Neufeld, B., Lee, J. D., Lindemann, D., Rapp, U. R., Ludwig, S. Extracellular signal regulated kinase 5 (erk5) is required for the differentiation of muscle cells EMBO Reports  2001 2:829-834  DOI:10.1093/embo-reports/kve177  PMID:11520859  PMCID:PMC1084032
  • Cleveland, J. L., Troppmair, J., Packham, G., Askew, D. S., Lloyd, P., Gonzalezgarcia, M., Nunez, G., Ihle, J. N., Rapp, U. R. V-raf suppresses apoptosis and promotes growth of interleukin-3-dependent myeloid cells Oncogene  1994 9:2217-2226  PMID:8036007
  • Storm, S. M., Cleveland, J. L., Rapp, U. R. Expression of raf family protooncogenes in normal mouse-tissues Oncogene  1990 5:345-351  PMID:1690378
  • Beck, T. W., Brennscheidt, U., Sithanandam, G., Cleveland, J., Rapp, U. R. Molecular-organization of the human raf-1 promoter region Molecular and Cellular Biology  1990 10:3325-3333  PMID:1694010  PMCID:PMC360752
  • Heidecker, G., Huleihel, M., Cleveland, J. L., Kolch, W., Beck, T. W., Lloyd, P., Pawson, T., Rapp, U. R. Mutational activation of c-raf-1 and definition of the minimal transforming sequence Molecular and Cellular Biology  1990 10:2503-2512  PMID:2188091  PMCID:PMC360607
  • Principato, M., Cleveland, J. L., Rapp, U. R., Holmes, K. L., Pierce, J. H., Morse, H. C., Klinken, S. P. Transformation of murine bone-marrow cells with combined v-raf-v-myc oncogenes yields clonally related mature b-cells and macrophages Molecular and Cellular Biology  1990 10:3562-3568  PMID:2162474  PMCID:PMC360791
  • Cleveland, J. L., Dean, M., Rosenberg, N., Wang, J. Y. J., Rapp, U. R. Tyrosine kinase oncogenes abrogate interleukin-3 dependence of murine myeloid cells through signaling pathways involving c-myc - conditional regulation of c-myc transcription by temperature-sensitive v-abl Molecular and Cellular Biology  1989 9:5685-5695  PMID:2555703  PMCID:PMC363740
  • Cleveland, J. L., Dean, M., Wang, J. Y., Hedge, A. M., Ihle, J. N., Rapp, U. R. Abrogation of il-3 dependence of myeloid fdc-p1 cells by tyrosine kinase oncogenes is associated with induction of c-myc Current Topics in Microbiology and Immunology  1988 141:300-309  PMID:3265092
  • Principato, M., Klinken, S. P., Cleveland, J. L., Rapp, U. R., Holmes, K. L., Pierce, J. H., Morse, H. C. In vitro transformation of murine bone marrow cells with a v-raf/v-myc retrovirus yields clonally related mature b cells and macrophages Current Topics in Microbiology and Immunology  1988 141:31-41  PMID:3265093
  • Cleveland, J. L., Morse, H. C., Rapp, U. R. Myc oncogenes and tumor-induction ISI Atlas of Science-Biochemistry  1988 1:93-100
  • Troppmair, J., Huleihel, M., Cleveland, J., Mushinski, J. F., Kurie, J., Morse, H. C., Wax, J. S., Potter, M., Rapp, U. R. Plasmacytoma induction by j series of v-myc recombinant retroviruses: Evidence for the requirement of two (raf and myc) oncogenes for transformation Current Topics in Microbiology and Immunology  1988 141:110-114  PMID:3215044
  • Rapp, U. R., Heidecker, G., Huleihel, M., Cleveland, J. L., Choi, W. C., Pawson, T., Ihle, J. N., Anderson, W. B. Raf family serine/threonine protein kinases in mitogen signal transduction Cold Spring Harbor Symposia on Quantitative Biology  1988 53:173-184  PMID:2978288
  • Farrar, W. L., Evans, S. W., Rapp, U. R., Cleveland, J. L. Effects of antiproliferative cyclic-amp on interleukin 2-stimulated gene-expression Journal of Immunology  1987 139:2075-2080  PMID:3040863
  • Weinstein, Y., Cleveland, J. L., Askew, D. S., Rapp, U. R., Ihle, J. N. Insertion and truncation of c-myb by murine leukemia-virus in a myeloid cell-line derived from cultures of normal hematopoietic-cells Journal of Virology  1987 61:2339-2343  PMID:2884332  PMCID:PMC283705
  • Cleveland, J. L., Rapp, U. R., Farrar, W. L. Role of c-myc and other genes in interleukin-2 regulated ct6 lymphocytes-t and their malignant variants Journal of Immunology  1987 138:3495-3504  PMID:3106484
  • Dean, M., Cleveland, J. L., Rapp, U. R., Ihle, J. N. Role of myc in the abrogation of il3 dependence of myeloid fdc-p1 cells Oncogene Research  1987 1:279-296  PMID:2453016
  • Huleihel, M., Goldsborough, M., Cleveland, J., Gunnell, M., Bonner, T., Rapp, U. R. Characterization of murine a-raf, a new oncogene related to the v-raf oncogene Molecular and Cellular Biology  1986 6:2655-2662  PMID:3491291  PMCID:PMC367822
  • Cleveland, J. L., Jansen, H. W., Bister, K., Fredrickson, T. N., Morse, H. C., Ihle, J. N., Rapp, U. R. Interaction between Raf and Myc oncogenes in transformation in vivo and in vitro Journal of Cellular Biochemistry  1986 30:195-218  DOI:10.1002/jcb.240300303  PMID:3084503
  • Morse, H. C., Hartley, J. W., Fredrickson, T. N., Yetter, R. A., Majumdar, C., Cleveland, J. L., Rapp, U. R. Recombinant murine retroviruses containing avian v-myc induce a wide spectrum of neoplasms in newborn mice Proceedings of the National Academy of Sciences of the United States of America  1986 83:6868-6872  DOI:10.1073/pnas.83.18.6868  PMID:3018749
  • Cleveland, J. L., Weinstein, Y., Ihle, J. N., Askew, D. S., Rapp, U. R. Transformation and insertional mutagenesis in vitro of primary hematopoietic stem cell cultures Current Topics in Microbiology and Immunology  1986 132:44-54  PMID:3024923
  • Morse, H. C., 3rd, Hartley, J. W., Fredrickson, T. N., Yetter, R. A., Cleveland, J. L., Majumdar, C., Rapp, U. R. Tumors of newborn nfs/n mice infected with murine retroviruses containing avian v-myc Current Topics in Microbiology and Immunology  1986 132:17-22  PMID:3024912
  • Rapp, U. R., Cleveland, J. L., Brightman, K., Scott, A., Ihle, J. N. Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes Nature  1985 317:434-438  DOI:10.1038/317434a0  PMID:3930972
  • Rapp, U. R., Cleveland, J. L., Fredrickson, T. N., Holmes, K. L., Morse, H. C., Jansen, H. W., Patschinsky, T., Bister, K. Rapid induction of hemopoietic neoplasms in newborn mice by a raf(mil)/myc recombinant murine retrovirus Journal of Virology  1985 55:23-33  PMID:4009794  PMCID:PMC254893
  • Blasi, E., Mathieson, B. J., Varesio, L., Cleveland, J. L., Borchert, P. A., Rapp, U. R. Selective immortalization of murine macrophages from fresh bone-marrow by a raf/myc recombinant murine retrovirus Nature  1985 318:667-670  DOI:10.1038/318667a0  PMID:4079980