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P300 assessment of chronic fatigue syndrome

Academic Article
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Overview

authors

  • Polich, John
  • Moore, A. P.
  • Wiederhold, M. D.

publication date

  • March 1995

journal

  • Journal of Clinical Neurophysiology  Journal

abstract

  • The P3(00) event-related brain potential (ERP) was elicited with an auditory tone-discrimination paradigm in 25 patients diagnosed with chronic fatigue syndrome (CFS) and 25 matched normal control subjects. Target stimulus probability was varied systematically (0.20, 0.50, 0.80) in different task conditions. No differences between the CFS and control subjects were found for either P3 amplitude or latency. No group effects were observed for the N1, P2, and N2 components. Despite the attentional and immediate memory deficits reported in CFS, the P3 ERP from auditory stimuli does not reliably discriminate CFS from matched control subjects.

subject areas

  • Acoustic Stimulation
  • Adult
  • Arousal
  • Attention
  • Cerebral Cortex
  • Evoked Potentials, Auditory
  • Fatigue Syndrome, Chronic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pitch Discrimination
  • Reaction Time
  • Reference Values
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Research

keywords

  • CHRONIC FATIGUE SYNDROME
  • ERP
  • P3(00)
  • PROBABILITY
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Identity

International Standard Serial Number (ISSN)

  • 0736-0258

Digital Object Identifier (DOI)

  • 10.1097/00004691-199503000-00009

PubMed ID

  • 7797633
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Additional Document Info

start page

  • 186

end page

  • 191

volume

  • 12

issue

  • 2

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