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Highly selective synthesis of heterosubstituted aromatic sulfamides

Academic Article
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Overview

related to degree

  • Hof, Fraser, Ph.D. in Chemistry, Scripps Research 1998 - 2003

authors

  • Hof, Fraser
  • Iovine, P. M.
  • Johnson, D. W.
  • Rebek Jr., Julius

publication date

  • December 2001

journal

  • Organic Letters  Journal

abstract

  • The sulfamide functional group is increasingly relevant in both medicinal and supramolecular chemistry, yet few selective synthetic steps are available for its elaboration. We report here a mild, general, and efficient method for the selective differentiation of N-atom substituents of aromatic sulfamides. [reaction: see text]

subject areas

  • Amides
  • Crystallography, X-Ray
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Sulfur Compounds
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Identity

International Standard Serial Number (ISSN)

  • 1523-7060

Digital Object Identifier (DOI)

  • 10.1021/ol0169731

PubMed ID

  • 11784189
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Additional Document Info

start page

  • 4247

end page

  • 4249

volume

  • 3

issue

  • 26

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