recent publications

• academic article

  • Paster, W., Bruger, A. M., Katsch, K., Gregoire, C., Roncagalli, R., Fu, G., Gascoigne, N. R. J., Nika, K., Cohnen, A., Feller, S. M., Simister, P. C., Molder, K. C., et al. A THEMIS:SHP1 complex promotes T-cell survival EMBO Journal  2015 34:393-409  DOI:10.15252/embj.201387725  PMID:25535246  PMCID:PMC4339124
  • Fu, G., Rybakin, V., Brzostek, J., Paster, W., Acuto, O., Gascoigne, N. R. J. Fine-tuning T cell receptor signaling to control T cell development Trends in Immunology  2014 35:311-318  DOI:10.1016/j.it.2014.05.003  PMID:24951034  PMCID:PMC4119814
  • Fu, G., Casas, J., Rigaud, S., Rybakin, V., Lambolez, F., Brzostek, J., Hoerter, J. A. H., Paster, W., Acuto, O., Cheroutre, H., Sauer, K., Gascoigne, N. R. J. Themis sets the signal threshold for positive and negative selection in T-cell development Nature  2013 504:441-445  DOI:10.1038/nature12718  PMID:24226767  PMCID:PMC3977001
  • Paster, W., Brockmeyer, C., Fu, G., Simister, P. C., de Wet, B., Martinez-Riano, A., Hoerter, J. A. H., Feller, S. M., Wulfing, C., Gascoigne, N. R. J., Acuto, O. GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development Journal of Immunology  2013 190:3749-3756  DOI:10.4049/jimmunol.1203389  PMID:23460737  PMCID:PMC3607403
  • Brockmeyer, C., Paster, W., Pepper, D., Tan, C. P., Trudgian, D. C., McGowan, S., Fu, G., Gascoigne, N. R. J., Acuto, O., Salek, M. T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component Journal of Biological Chemistry  2011 286:7535-7547  DOI:10.1074/jbc.M110.201236  PMID:21189249  PMCID:PMC3045008
  • Fu, G., Vallee, S., Rybakin, V., McGuire, M. V., Ampudia, J., Brockmeyer, C., Salek, M., Fallen, P. R., Hoerter, J. A. H., Munshi, A., Huang, Y. H., Hu, J. F., et al. Themis controls thymocyte selection through regulation of t cell antigen receptor-mediated signaling Nature Immunology  2009 10:848-856  DOI:10.1038/ni.1766  PMID:19597499  PMCID:PMC2757056