recent publications

• academic article

  • Gao, H., Li, L., Rao, S., Shen, G., Xi, Q., Chen, S., Zhang, Z., Wang, K., Ellis, S. G., Chen, Q., Topol, E. J., Wang, Q. K. Genome-wide linkage scan identifies two novel genetic loci for coronary artery disease: in GeneQuest families PLoS One  2014 9:e113935  DOI:10.1371/journal.pone.0113935  PMID:25485937  PMCID:PMC4259362
  • Shen, G. Q., Girelli, D., Li, L., Rao, S., Archacki, S., Olivieri, O., Martinelli, N., Park, J. E., Chen, Q., Topol, E. J., Wang, Q. K. A novel molecular diagnostic marker for familial and early-onset coronary artery disease and myocardial infarction in the LRP8 gene Circulation-Cardiovascular Genetics  2014 7:514-520  DOI:10.1161/circgenetics.113.000321  PMID:24867879  PMCID:PMC4140990
  • Shen, G. Q., Girelli, D., Li, L., Olivieri, O., Martinelli, N., Chen, Q., Topol, E. J., Wang, Q. K. Multi-allelic haplotype association identifies novel information different from single-SNP analysis: A new protective haplotype in the LRP8 gene is against familial and early-onset CAD and MI Gene  2013 521:78-81  DOI:10.1016/j.gene.2013.03.022  PMID:23524007  PMCID:PMC3919654
  • Archacki, S. R., Angheloiu, G., Moravec, C. S., Liu, H., Topol, E. J., Wang, Q. K. Comparative gene expression analysis between coronary arteries and internal mammary arteries identifies a role for the tes gene in endothelial cell functions relevant to coronary artery disease Human Molecular Genetics  2012 21:1364-1373  DOI:10.1093/hmg/ddr574  PMID:22156939
  • Yang, R., Li, L., Seidelmann, S. B., Shen, G. Q., Sharma, S., Rao, S. Q., Abdullah, K. G., MacKinlay, K. G., Elston, R. C., Chen, Q. Y., Topol, E. J., Wang, Q. K. A genome-wide linkage scan identifies multiple quantitative trait loci for hdl-cholesterol levels in families with premature cad and mi Journal of Lipid Research  2010 51:1442-1451  DOI:10.1194/jlr.M004325  PMID:20075193  PMCID:PMC3035507
  • Abdullah, K. G., Li, L., Shen, G. Q., Hu, Y., Yang, Y., MacKinlay, K. G., Topol, E. J., Wang, Q. K. Four snps on chromosome 9p21 confer risk to premature, familial cad and mi in an american caucasian population (genequest) Annals of Human Genetics  2008 72:654-657  DOI:10.1111/j.1469-1809.2008.00454.x  PMID:18505420  PMCID:PMC2634771
  • Seidelmann, S. B., Li, L., Shen, G. Q., Topol, E. J., Wang, Q. K. Identification of a novel locus for triglyceride on chromosome 1p31-32 in families with premature cad and mi Journal of Lipid Research  2008 49:1034-1038  DOI:10.1194/jlr.M700576-JLR200  PMID:18245017  PMCID:PMC2311437
  • Shen, G. Q., Li, L., Girelli, D., Seidelmann, S. B., Rao, S., Fan, C., Park, J. E., Xi, Q., Li, J., Hu, Y., Olivieri, O., Marchant, K., et al. An lrp8 variant is associated with familial and premature coronary artery disease and myocardial infarction American Journal of Human Genetics  2007 81:780-791  DOI:10.1086/521581  PMID:17847002  PMCID:PMC2227927
  • Topol, E. J., Smith, J., Plow, E. F., Wang, Q. K. Genetic susceptibility to myocardial infarction and coronary artery disease Human Molecular Genetics  2006 15:R117-R123  DOI:10.1093/hmg/ddl183  PMID:16987874