recent publications

• academic article

  • Emerling, B. M., Hurov, J. B., Poulogiannis, G., Tsukazawa, K. S., Choo-Wing, R., Wulf, G. M., Bell, E. L., Shim, H. S., Lamia, K. A., Rameh, L. E., Bellinger, G., Sasaki, A. T., et al. Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors Cell  2013 155:844-857  DOI:10.1016/j.cell.2013.09.057  PMID:24209622  PMCID:PMC4070383
  • Chen, Z., Cheng, K., Walton, Z., Wang, Y. C., Ebi, H., Shimamura, T., Liu, Y., Tupper, T., Ouyang, J., Li, J., Gao, P., Woo, M. S., et al. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response Nature  2012 483:613-617  DOI:10.1038/nature10937  PMID:22425996  PMCID:PMC3385933
  • Shaw, R. J., Lamia, K. A., Vasquez, D., Koo, S. H., Bardeesy, N., DePinho, R. A., Montminy, M., Cantley, L. C. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin Science  2005 310:1642-1646  DOI:10.1126/science.1120781  PMID:16308421  PMCID:PMC3074427
  • Lamia, K. A., Peroni, O. D., Kim, Y. B., Rameh, L. E., Kahn, B. B., Cantley, L. C. Increased insulin sensitivity and reduced adiposity in phosphatidylinositol 5-phosphate 4-kinase beta(-/-) mice Molecular and Cellular Biology  2004 24:5080-5087  DOI:10.1128/mcb.24.11.5080-5087.2004  PMID:15143198  PMCID:PMC416424
  • Carricaburu, V., Lamia, K. A., Lo, E., Favereaux, L., Payrastre, B., Cantley, L. C., Rameh, L. E. The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation Proceedings of the National Academy of Sciences of the United States of America  2003 100:9867-9872  DOI:10.1073/pnas.1734038100  PMID:12897244  PMCID:PMC187868
  • Field, S. J., Lamia, K. A., Rameh, L. E., Cantley, L. C. Lipid research picks up speed on the slopes of Taos Developmental Cell  2002 2:407-410  DOI:10.1016/s1534-5807(02)00150-8  PMID:11970891
  • Parker, D., Jhala, U. S., Radhakrishnan, I., Yaffe, M. B., Reyes, C., Shulman, A. I., Cantley, L. C., Wright, P. E., Montminy, M. Analysis of an activator : Coactivator complex reveals an essential role for secondary structure in transcriptional activation Molecular Cell  1998 2:353-359  DOI:10.1016/s1097-2765(00)80279-8  PMID:9774973
  • Chang, H. W., Aoki, M., Fruman, D., Auger, K. R., Bellacosa, A., Tsichlis, P. N., Cantley, L. C., Roberts, T. M., Vogt, P. K. Transformation of chicken cells by the gene encoding the catalytic subunit of pi 3-kinase Science  1997 276:1848-1850  DOI:10.1126/science.276.5320.1848  PMID:9188528