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Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin

Academic Article
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Overview

authors

  • Cooke, H. A.
  • Zhang, J.
  • Griffin, M. A.
  • Nonaka, K.
  • Van Lanen, S. G.
  • Shen, Ben
  • Bruner, S. D.

publication date

  • June 2007

journal

  • Journal of the American Chemical Society  Journal

subject areas

  • Antibiotics, Antineoplastic
  • Bacterial Proteins
  • Carboxylic Acids
  • Coenzyme A
  • Gene Expression Regulation, Bacterial
  • Molecular Structure
  • Multigene Family
  • Naphthalenes
  • Streptomyces
  • Zinostatin
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Identity

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja071886a

PubMed ID

  • 17539640
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Additional Document Info

start page

  • 7728

end page

  • 7729

volume

  • 129

issue

  • 25

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