recent publications

• academic article

  • Ruffner, H., Joazeiro, C. A. P., Hemmati, D., Hunter, T., Verma, I. M. Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity Proceedings of the National Academy of Sciences of the United States of America  2001 98:5134-5139  DOI:10.1073/pnas.081068398  PMID:11320250  PMCID:PMC33176
  • Reis, L. F. L., Ruffner, H., Stark, G., Aguet, M., Weissmann, C. Mice devoid of interferon regulatory factor-1 (irf-1) show normal expression of type-i interferon genes EMBO Journal  1994 13:4798-4806  PMID:7957048  PMCID:PMC395418
  • Ruffner, H., Reis, L. F. L., Naf, D., Weissmann, C. Induction of type-i interferon genes and interferon-inducible genes in embryonal stem-cells devoid of interferon regulatory factor-i Proceedings of the National Academy of Sciences of the United States of America  1993 90:11503-11507  DOI:10.1073/pnas.90.24.11503  PMID:8265581
  • Macdonald, N. J., Kuhl, D., Maguire, D., Naf, D., Gallant, P., Goswamy, A., Hug, H., Bueler, H., Chaturvedi, M., Delafuente, J., Ruffner, H., Meyer, F., et al. Different pathways mediate virus inducibility of the human ifn-alpha-1 and ifn-beta genes Cell  1990 60:767-779  DOI:10.1016/0092-8674(90)90091-r  PMID:2107026