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Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors

Academic Article
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Overview

authors

  • Fang, X. A.
  • Chen, Y. T.
  • Sessions, E. H.
  • Chowdhury, S.
  • Vojkovsky, T.
  • Yin, Y.
  • Pocas, J. R.
  • Grant, W.
  • Schroter, T.
  • Lin, L.
  • Ruiz, C.
  • Cameron, Michael
  • LoGrasso, Philip
  • Bannister, Thomas
  • Feng, Yangbo

publication date

  • March 2011

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Protein Kinase Inhibitors
  • Quinazolinones
  • Structure-Activity Relationship
  • rho-Associated Kinases
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Research

keywords

  • Protein kinase A
  • Pyrazole
  • Quinazolinone
  • ROCK inhibitor
  • Rho kinase
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2011.01.039

PubMed ID

  • 21349713
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Additional Document Info

start page

  • 1844

end page

  • 1848

volume

  • 21

issue

  • 6

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