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Lovastatin ameliorates alpha-synuclein accumulation and oxidation in transgenic mouse models of alpha-synucleinopathies

Academic Article
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  • Overview
  • Research
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Overview

authors

  • Koob, A. O.
  • Ubhi, K.
  • Paulsson, J. F.
  • Kelly, Jeffery
  • Rockenstein, E.
  • Mante, M.
  • Adame, A.
  • Masliah, E.

publication date

  • February 2010

journal

  • Experimental Neurology  Journal

subject areas

  • Analysis of Variance
  • Animals
  • Antigens, Thy-1
  • Brain
  • Cholesterol
  • Dendrites
  • Disease Models, Animal
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Lewy Body Disease
  • Lovastatin
  • Mice
  • Mice, Transgenic
  • Microtubule-Associated Proteins
  • Neurons
  • Oxidation-Reduction
  • Parkinson Disease
  • Platelet-Derived Growth Factor
  • alpha-Synuclein
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Research

keywords

  • Cholesterol inhibitors
  • Dementia with Lewy bodies
  • Neurodegeneration
  • Parkinson's disease
  • Statins
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Identity

PubMed Central ID

  • PMC2812599

International Standard Serial Number (ISSN)

  • 0014-4886

Digital Object Identifier (DOI)

  • 10.1016/j.expneurol.2009.11.015

PubMed ID

  • 19944097
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Additional Document Info

start page

  • 267

end page

  • 274

volume

  • 221

issue

  • 2

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