Helper t-cell-regulated b-cell immunity

Academic Article

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• Research
• Identity
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Overview

authors

• McHeyzer-Williams, Michael G.
• McHeyzer-Williams, L.
• Panus, J.
• Pogue-Caley, R.
• Bikah, G.
• Driver, D.
• Eisenbraun, M.

publication date

• March 2003

journal

• Microbes and Infection  Journal

abstract

• Helper T-cell-regulated B-cell responses constitute a major component of the immune response to many pathogens. Spatially and temporally organized cognate intercellular communication within secondary lymphoid organs is the critical regulating event in this complex adaptive response to antigen. Here, we discuss what is known of these molecular exchanges and their cellular consequences in a serial synapsis model of adaptive immunity.

subject areas

• Antigens, Differentiation, T-Lymphocyte
• B-Lymphocytes
• Gene Expression Regulation
• Humans
• Immunity, Active
• Immunologic Memory
• T-Lymphocytes, Helper-Inducer

Research

keywords

• B lymphocytes
• T lymphocytes
• helper-inducer
• immunologic memory
• subsets

Identity

International Standard Serial Number (ISSN)

• 1286-4579

Digital Object Identifier (DOI)

• 10.1016/s1286-4579(03)00012-1

PubMed ID

• 12681409

Additional Document Info

start page

• 205

end page

• 212

volume

• 5

issue

• 3